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Microbiology

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Overview

Walter J. Urba is affiliated with Providence Portland Medical Center in the United States. Their research spans multiple areas within medicine, biochemistry, genetics, and molecular biology, with significant contributions focused on oncology, molecular biology, immunology, infectious diseases, and pulmonary and respiratory medicine.

The scientist's main topics of work include:

  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • Cancer Genomics and Diagnostics
  • Colorectal Cancer Treatments and Studies
  • SARS-CoV-2 and COVID-19 Research
  • Vaccines and immunoinformatics approaches

Among the recent publications associated with Walter J. Urba are:

  • "Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer" (2022) in the New England Journal of Medicine
  • "Combination Dabrafenib and Trametinib Versus Combination Nivolumab and Ipilimumab for Patients With Advanced BRAF-Mutant Melanoma: The DREAMseq Trial-ECOG-ACRIN EA6134" (2022) in the Journal of Clinical Oncology
  • "Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma" (2020) in Cancer Cell
  • "Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamous cell carcinoma" (2021) in the Journal for ImmunoTherapy of Cancer
  • "Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells" (2021) in Nature Communications

Frequent coauthors who have collaborated extensively with Walter J. Urba include:

  • William L. Redmond
  • Rom S. Leidner
  • Brian Piening
  • Carlo Bifulco
  • Yoshinobu Koguchi

Walter J. Urba's work has been published frequently in venues such as:

  • Regular and Young Investigator Award Abstracts
  • Cancer Research
  • Journal of Clinical Oncology
  • Journal for ImmunoTherapy of Cancer
  • bioRxiv (Cold Spring Harbor Laboratory)

The scientist's research primarily falls within the fields of Medicine and Biochemistry, Genetics, and Molecular Biology with a heavy emphasis on applied oncology and immunological responses related to cancer treatment and immunotherapy developments.

Best Publications

  • Improved Survival with Ipilimumab in Patients with Metastatic Melanoma.

    F. Stephen Hodi;Steven J. O'Day;David F. McDermott;Robert W. Weber

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab.

    Nadeem Riaz;Jonathan J. Havel;Vladimir Makarov;Alexis Desrichard

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma

    David F. McDermott;Meredith M. Regan;Joseph I. Clark;Lawrence E. Flaherty

  • Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.

    André Kahles;Kjong-Van Lehmann;Nora C Toussaint;Matthias Hüser

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Randomized Phase III Study of Docetaxel Compared With Paclitaxel in Metastatic Breast Cancer

    S.E. Jones;J. Erban;B. Overmoyer;G.T. Budd

  • Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

    Matthew H. Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • OX40 is a potent immune-stimulating target in late-stage cancer patients.

    Brendan D. Curti;Magdalena Kovacsovics-Bankowski;Nicholas Morris;Edwin Walker

  • Phase I/II study of ipilimumab for patients with metastatic melanoma

    Jeffrey S. Weber;Steven O’Day;Walter Urba;John Powderly

  • Combination Dabrafenib and Trametinib Versus Combination Nivolumab and Ipilimumab for Patients With Advanced BRAF-Mutant Melanoma: The DREAMseq Trial—ECOG-ACRIN EA6134

    Unknown

  • Engagement of the OX-40 Receptor In Vivo Enhances Antitumor Immunity

    Andrew D. Weinberg;Martin Muy Rivera;Rodney Prell;Arden Morris

  • Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer

    Unknown

  • Conventional-dose salvage combination chemotherapy in patients relapsing with Hodgkin's disease after combination chemotherapy: the low probability for cure.

    D L Longo;P L Duffey;R C Young;S M Hubbard

  • Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

    Franz X. Schaub;Varsha Dhankani;Ashton C. Berger;Mihir Trivedi

  • Adjuvant High-Dose Bolus Interleukin-2 for Patients With High-Risk Renal Cell Carcinoma: A Cytokine Working Group Randomized Trial

    Joseph I. Clark;Michael B. Atkins;Walter J. Urba;Steven Creech

  • Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): a novel strategy for the treatment of melanoma and other malignancies.

    Steven J. O'Day;Omid Hamid;Walter J. Urba

  • Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma

    Jedd D. Wolchok;F. Stephen Hodi;Jeffrey S. Weber;James P. Allison

  • Exacerbation of symptoms of autoimmune disease in patients receiving alpha‐interferon therapy

    Kevin C. Conlon;Walter J. Urba;John W. Smithii;Ronald G. Steis

  • Results from an integrated safety analysis of urelumab, an agonist anti-CD137 monoclonal antibody

    Neil H Segal;Theodore F Logan;F. Stephen Hodi;David F. McDermott

Frequent Co-Authors

Bernard A. FoxEarle
Bernard A. FoxEarle Earle A. Chiles Research Institute
Dan L. Longo
Dan L. Longo Harvard University
F. Stephen Hodi
F. Stephen Hodi Harvard University
David F. McDermott
David F. McDermott Beth Israel Deaconess Medical Center
Jedd D. Wolchok
Jedd D. Wolchok Cornell University
Kim Margolin
Kim Margolin City Of Hope National Medical Center
Steven J. O'Day
Steven J. O'Day St. John's University
Mario Sznol
Mario Sznol Yale University
Thomas F. Gajewski
Thomas F. Gajewski University of Chicago
Jeffrey W. Clark
Jeffrey W. Clark Harvard University

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