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Biology and Biochemistry

D-Index
60
Citations
12371
World Ranking
11994
National Ranking
5145

Overview

Phoebe L. Stewart is affiliated with Case Western Reserve University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant focus in Genetics, Molecular Biology, Oncology, Infectious Diseases, and Biotechnology.

The scientist has contributed extensively to virus-based gene therapy research and related areas. Their work also covers viral infectious diseases and gene expression in insects, CAR-T cell therapy research, CRISPR and genetic engineering, viral gastroenteritis research and epidemiology, cancer research and treatments, and studies of bacterial biofilms and quorum sensing.

Recent published papers by Phoebe L. Stewart include the following:

  • "Systemic cancer therapy with engineered adenovirus that evades innate immunity," 2020, Science Translational Medicine
  • "Human Immunodeficiency Virus-Associated Exosomes Promote Kaposi's Sarcoma-Associated Herpesvirus Infection via the Epidermal Growth Factor Receptor," 2020, Journal of Virology
  • "Cryo-EM Structures of CusA Reveal a Mechanism of Metal-Ion Export," 2021, mBio
  • "Targeted, safe, and efficient gene delivery to human hematopoietic stem and progenitor cells in vivo using the engineered AVID adenovirus vector platform," 2023, Molecular Therapy
  • "Structural Model for Factor X Inhibition of IgM and Complement-Mediated Neutralization of Adenovirus," 2023, Viruses

The frequent co-authors collaborating with Stewart include:

  • Dmitry M. Shayakhmetov
  • Svetlana Atasheva
  • Corey C. Emerson
  • Jia Yao
  • Nicole Wagner

Stewart's work has appeared repeatedly in several publication venues, including Molecular Therapy and Viruses, each hosting two of Stewart's publications. Other venues include Science Translational Medicine, mBio, and Journal of Virology.

Best Publications

  • Mutation R120G in αB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

    Michael P. Bova;Orna Yaron;Qingling Huang;Linlin Ding

  • Restricted Receptor Segregation into Membrane Microdomains Occurs on Human T Cells During Apoptosis Induced by Galectin-1

    Karen E. Pace;Christina Lee;Phoebe L. Stewart;Linda G. Baum

  • The Mannose Receptor Delivers Lipoglycan Antigens to Endosomes for Presentation to T Cells by CD1b Molecules

    Theodore I Prigozy;Peter A Sieling;Daniel Clemens;Phoebe L Stewart

  • The small heat-shock protein, αb-crystallin, has a variable quaternary structure

    Dana A Haley;Joseph Horwitz;Phoebe L Stewart

  • Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo

    O. Kalyuzhniy;N. C. Di Paolo;M. Silvestry;S. E. Hofherr

  • Role of αv Integrins in Adenovirus Cell Entry and Gene Delivery

    Glen R. Nemerow;Phoebe L. Stewart

  • Cell integrins: commonly used receptors for diverse viral pathogens

    Phoebe L. Stewart;Glen R. Nemerow

  • Structure and mechanism of protein stability sensors: chaperone activity of small heat shock proteins.

    Hassane S. Mchaourab;Jared A. Godar;Phoebe L. Stewart

  • Crystal Structure of Human Adenovirus at 3.5 Å Resolution

    Vijay S. Reddy;S. Kundhavai Natchiar;Phoebe L. Stewart;Glen R. Nemerow

  • Lens α-crystallin: Function and structure

    Joseph Horwitz;Michael P Bova;Lin Lin Ding;Dana A Haley;Dana A Haley

  • Small heat-shock protein structures reveal a continuum from symmetric to variable assemblies.

    Dana A. Haley;Michael P. Bova;Qing Ling Huang;Hassane S. Mchaourab

  • Protein structure by solid-state NMR spectroscopy.

    S. J. Opella;Phoebe L. Stewart;K. G. Valentine

  • Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization

    Phoebe L. Stewart;Charles Y. Chiu;Shuang Huang;Tom Muir

  • Structure of adenovirus complexed with its internalization receptor, alphavbeta5 integrin

    Charles Y. Chiu;Patricia Mathias;Glen R. Nemerow;Phoebe L. Stewart

  • Flexibility of the Adenovirus Fiber Is Required for Efficient Receptor Interaction

    Eugene Wu;Lars Pache;Dan J. Von Seggern;Tina Marie Mullen

  • Structure of the vault, a ubiquitous celular component

    Lawrence B Kong;Amara C Siva;Leonard H Rome;Phoebe L Stewart

  • Visualization of α-Helices in a 6-Ångstrom Resolution Cryoelectron Microscopy Structure of Adenovirus Allows Refinement of Capsid Protein Assignments

    Susan D. Saban;Mariena Silvestry;Glen R. Nemerow;Phoebe L. Stewart

  • Coagulation Factor X Activates Innate Immunity to Human Species C Adenovirus

    Konstantin Doronin;Justin W. Flatt;Nelson C. Di Paolo;Reeti Khare

  • Elucidating the Ticking of an In Vitro Circadian Clockwork

    Tetsuya Mori;Dewight R Williams;Mark O Byrne;Ximing Qin

  • The Cyanobacterial Circadian System: From Biophysics to Bioevolution

    Carl Hirschie Johnson;Phoebe L. Stewart;Martin Egli

Frequent Co-Authors

Glen R. Nemerow
Glen R. Nemerow Scripps Research Institute
Nicole F. Steinmetz
Nicole F. Steinmetz University of California, San Diego
Hassane S. Mchaourab
Hassane S. Mchaourab Vanderbilt University
Jens Meiler
Jens Meiler Vanderbilt University
Leonard H. Rome
Leonard H. Rome University of California, Los Angeles
Martin Egli
Martin Egli Vanderbilt University
Charles Y. Chiu
Charles Y. Chiu University of California, San Francisco
Carl Hirschie Johnson
Carl Hirschie Johnson Vanderbilt University
Krzysztof Palczewski
Krzysztof Palczewski University of California, Irvine
Stanley J. Opella
Stanley J. Opella University of California, San Diego

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