World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
130
Citations
60120
World Ranking
190
National Ranking
118

Biology and Biochemistry

D-Index
133
Citations
62733
World Ranking
373
National Ranking
246

Medicine

D-Index
133
Citations
62657
World Ranking
2240
National Ranking
1265

Overview

David T. Curiel is affiliated with Washington University in St. Louis in the United States. Their research spans multiple fields, primarily focusing on Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these broad disciplines, their work delves into subfields such as Molecular Biology, Genetics, Infectious Diseases, Oncology, and Immunology.

The scientist's research topics cover a diverse range of studies including Virus-based gene therapy research, CRISPR and Genetic Engineering, RNA Interference and Gene Delivery, SARS-CoV-2 and COVID-19 Research, CAR-T cell therapy research, Viral Infectious Diseases and Gene Expression in Insects, and COVID-19 Clinical Research Studies.

Frequent co-authors collaborating with David T. Curiel include:

  • Igor P. Dmitriev
  • Elena A. Kashentseva
  • Michael Diamond
  • Zhi Hong Lu
  • Paul J. Rice-Boucher

Their publications are often found in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Nature Immunology
  • Molecular Therapy
  • Preprints.org

Recent papers authored or co-authored by David T. Curiel highlight work in virology, gene therapy, and vaccine development. Some notable publications include:

  • "A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2" (2020, Cell)
  • "Adenoviral vector vaccine platforms in the SARS-CoV-2 pandemic" (2021, npj Vaccines)
  • "Neural stem cell delivery of an oncolytic adenovirus in newly diagnosed malignant glioma: a first-in-human, phase 1, dose-escalation trial" (2021, The Lancet Oncology)
  • "An intranasal vaccine durably protects against SARS-CoV-2 variants in mice" (2021, Cell Reports)
  • "A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques" (2021, Cell Reports Medicine)

Best Publications

  • Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity.

    Tyler J Curiel;Shuang Wei;Haidong Dong;Xavier Alvarez

  • An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism.

    Igor Dmitriev;Victor Krasnykh;C. Ryan Miller;Minghui Wang

  • Adenovirus enhancement of transferrin-polylysine-mediated gene delivery.

    David T. Curiel;Santosh Agarwal;Ernst Wagner;Matt Cotten

  • Engineering targeted viral vectors for gene therapy

    Reinhard Waehler;Stephen J. Russell;David T. Curiel

  • Corneal avascularity is due to soluble VEGF receptor-1

    Balamurali K. Ambati;Miho Nozaki;Nirbhai Singh;Atsunobu Takeda

  • Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells.

    Weiping Zou;Weiping Zou;Véronique Machelon;Aurore Coulomb-L'Hermin;Jozef Borvak

  • Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.

    Ernst Wagner;Kurt Zatloukal;Matt Cotten;Helen Kirlappos

  • Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Lung Cancer Study Group.

    Chiba I;Takahashi T;Nau Mm;D'Amico D

  • Replicative adenoviruses for cancer therapy.

    Ramon Alemany;Cristina Balagué;David T. Curiel

  • Targeted gene delivery by tropism-modified adenoviral vectors

    Joanne T. Douglas;Buck E. Rogers;Maryland E. Rosenfeld;Sharon I. Michael

  • A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2.

    Ahmed O. Hassan;Natasha M. Kafai;Igor P. Dmitriev;Julie M. Fox

  • Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate.

    C. K. Goldman;R. L. Kendall;G. Cabrera;L. Soroceanu

  • High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles

    Matt Cotten;Ernst Wagner;Kurt Zatloukal;Stephen Phillips

  • Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism.

    Victor N. Krasnykh;Galina V. Mikheeva;Joanne T. Douglas;David T. Curiel

  • Differential Susceptibility of Primary and Established Human Glioma Cells to Adenovirus Infection: Targeting via the Epidermal Growth Factor Receptor Achieves Fiber Receptor-independent Gene Transfer

    C R Miller;D J Buchsbaum;P N Reynolds;J T Douglas

  • Characterization of a messenger RNA polynucleotide vaccine vector

    R. M. Conry;A. F. LoBuglio;M. Wright;L. Sumerel

  • High-efficiency gene transfer mediated by adenovirus coupled to DNA-polylysine complexes.

    David T. Curiel;Ernst Wagner;Matt Cotten;Max L. Birnstiel

  • Blood clearance rates of adenovirus type 5 in mice.

    Ramon Alemany;Kaori Suzuki;David T. Curiel

  • Adenovirus type 5 fiber knob binds to MHC class I α2 domain at the surface of human epithelial and B lymphoblastoid cells

    Saw See Hong;Lucie Karayan;Jeannette Tournier;David T. Curiel

  • Conjugates for introducing nucleic acid into higher eucaryotic cells

    David T. Curiel;Ping-chuan Hu;Max L. Birnstiel;Matthew Cotten

Frequent Co-Authors

Igor Dmitriev
Igor Dmitriev Washington University in St. Louis
Gene P. Siegal
Gene P. Siegal University of Alabama at Birmingham
Ronald D. Alvarez
Ronald D. Alvarez Vanderbilt University Medical Center
Victor Krasnykh
Victor Krasnykh The University of Texas MD Anderson Cancer Center
Paul Dent
Paul Dent Virginia Commonwealth University
Akseli Hemminki
Akseli Hemminki University of Helsinki
Paul B. Fisher
Paul B. Fisher Virginia Commonwealth University
Steven Grant
Steven Grant Virginia Commonwealth University
Ernst Wagner
Ernst Wagner Ludwig-Maximilians-Universität München
Devanand Sarkar
Devanand Sarkar Virginia Commonwealth University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you’re studying Biology or Biochemistry in the USA, there are a variety of flexible online degrees and career certifications to explore. For students interested in mental health, psychiatric np programs offer a fast, specialized pathway into psychiatric nursing—an area with growing demand.

Those passionate about diet and wellness can benefit from a fast track nutrition degree, which accelerates your studies to enter the nutrition workforce quickly. For aspiring healthcare leaders, an online healthcare mba programs can open doors to management and executive roles in hospitals or biotech firms.

Certifications also play a key role in healthcare careers. If you’re considering medical coding, compare ccs vs cpc credentials to understand the differences, costs, and salary prospects. With online options and diverse career pathways, your Biology or Biochemistry background can lead to many rewarding opportunities in science and healthcare.

Best Scientists Citing David T. Curiel

Trending Scientists