World's Best Scientists 2026 revealed!
Hiroyuki Mizuguchi

Hiroyuki Mizuguchi

D-Index & Metrics

Molecular Biology

D-Index
79
Citations
22186
World Ranking
1039
National Ranking
80

Hiroyuki Mizuguchi publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Hiroyuki Mizuguchi sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 547 publications — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

Hiroyuki Mizuguchi D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Hiroyuki Mizuguchi sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 79 D-Index — 67th percentile

67% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Overview

Hiroyuki Mizuguchi is affiliated with Osaka University in Japan and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their work spans multiple subfields, including molecular biology, genetics, oncology, biomedical engineering, and surgery.

The scientist's research touches on several main topics such as virus-based gene therapy research, 3D printing in biomedical research, pluripotent stem cells research, pancreatic function and diabetes, cancer research and treatments, viral infectious diseases and gene expression in insects, and liver physiology and pathology.

Frequent publication venues for Mizuguchi include Drug Metabolism and Pharmacokinetics, Scientific Reports, Biological and Pharmaceutical Bulletin, PLoS ONE, and Drug Delivery System.

Recent papers authored or co-authored by Mizuguchi include:

  • Adenovirus vector-based vaccine for infectious diseases, 2021, Drug Metabolism and Pharmacokinetics
  • Immune Modulation by Telomerase-Specific Oncolytic Adenovirus Synergistically Enhances Antitumor Efficacy with Anti-PD1 Antibody, 2020, Molecular Therapy
  • Monolayer platform using human biopsy-derived duodenal organoids for pharmaceutical research, 2021, Molecular Therapy - Methods & Clinical Development
  • Usability of Polydimethylsiloxane-Based Microfluidic Devices in Pharmaceutical Research Using Human Hepatocytes, 2021, ACS Biomaterials Science & Engineering
  • Oncolytic Virus-Mediated Targeting of the ERK Signaling Pathway Inhibits Invasive Propensity in Human Pancreatic Cancer, 2020, Molecular Therapy - Oncolytics

Mizuguchi has collaborated frequently with several researchers, including:

  • Fuminori Sakurai
  • Kazuo Takayama
  • Yukiko Ueyama-Toba
  • Tomoki Yamashita
  • Jumpei Yokota

Best Publications

  • IRES-Dependent Second Gene Expression Is Significantly Lower Than Cap-Dependent First Gene Expression in a Bicistronic Vector

    Hiroyuki Mizuguchi;Zhili Xu;Akiko Ishii-Watabe;Eriko Uchida

  • Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method

    Hiroyuki Mizuguchi;Mark A. Kay

  • A simple method for constructing E1- and E1/E4-deleted recombinant adenoviral vectors.

    Hiroyuki Mizuguchi;Mark A. Kay

  • Expression cloning of a cDNA encoding the bovine histamine H1 receptor.

    Masakatsu Yamashita;Hiroyuki Fukui;Kazushige Sugama;Yoshiyuki Horio

  • Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity.

    Kenji Uno;Hideki Katagiri;Tetsuya Yamada;Yasushi Ishigaki

  • Quantitative Comparison of Intracellular Trafficking and Nuclear Transcription between Adenoviral and Lipoplex Systems

    Susumu Hama;Hidetaka Akita;Rie Ito;Hiroyuki Mizuguchi

  • 3D spheroid culture of hESC/hiPSC-derived hepatocyte-like cells for drug toxicity testing

    Kazuo Takayama;Kenji Kawabata;Yasuhito Nagamoto;Keisuke Kishimoto

  • A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob

    H Mizuguchi;N Koizumi;N Koizumi;T Hosono;N Utoguchi

  • Efficient Generation of Functional Hepatocytes From Human Embryonic Stem Cells and Induced Pluripotent Stem Cells by HNF4α Transduction

    Kazuo Takayama;Mitsuru Inamura;Kenji Kawabata;Kazufumi Katayama

  • A novel PPARγ gene therapy to control inflammation associated with inflammatory bowel disease in a murine model

    Kazufumi Katayama;Koichiro Wada;Atsushi Nakajima;Hiroyuki Mizuguchi

  • A Novel Murine Model of Graves’ Hyperthyroidism with Intramuscular Injection of Adenovirus Expressing the Thyrotropin Receptor

    Yuji Nagayama;Masako Kita-Furuyama;Takao Ando;Kazuhiko Nakao

  • Optimization of transcriptional regulatory elements for constructing plasmid vectors.

    Zhi-Li Xu;Hiroyuki Mizuguchi;Akiko Ishii-Watabe;Eriko Uchida

  • Autoinhibitory Regulation of p73 by ΔNp73 To Modulate Cell Survival and Death through a p73-Specific Target Element within the ΔNp73 Promoter

    Takahito Nakagawa;Masato Takahashi;Toshinori Ozaki;Ken-ichi Watanabe

  • Targeted Adenovirus Vectors

    Hiroyuki Mizuguchi;Takao Hayakawa

  • In vivo imaging of lymph node metastasis with telomerase-specific replication-selective adenovirus

    Hiroyuki Kishimoto;Toru Kojima;Yuichi Watanabe;Shunsuke Kagawa

  • Targeted delivery of CX3CL1 to multiple lung tumors by mesenchymal stem cells.

    Hong Xin;Masahiko Kanehira;Hiroyuki Mizuguchi;Takao Hayakawa

  • Targeted delivery of NK4 to multiple lung tumors by bone marrow-derived mesenchymal stem cells

    M Kanehira;H Xin;K Hoshino;M Maemondo

  • Protective mucosal immunity mediated by epithelial CD1d and IL-10

    Torsten Olszak;Joana F. Neves;C. Marie Dowds;Kristi Baker

  • A novel strategy for the enhancement of drug absorption using a claudin modulator.

    Masuo Kondoh;Akane Masuyama;Azusa Takahashi;Nagayoshi Asano

  • Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes

    Kazuo Takayama;Yuta Morisaki;Shuichi Kuno;Yasuhito Nagamoto

Frequent Co-Authors

Takao Hayakawa
Takao Hayakawa National Institutes of Health
Shinsaku Nakagawa
Shinsaku Nakagawa Osaka University
Tadanori Mayumi
Tadanori Mayumi Kobe Gakuin University
Naoki Okada
Naoki Okada Osaka University
Toshiyoshi Fujiwara
Toshiyoshi Fujiwara Okayama University
Takuya Fujita
Takuya Fujita Ritsumeikan University
Ken Hirotsu
Ken Hirotsu Osaka Metropolitan University
Hiroyuki Kagamiyama
Hiroyuki Kagamiyama Osaka Medical College
Kosaku Uyeda
Kosaku Uyeda The University of Texas Southwestern Medical Center
Yoshiyuki Horio
Yoshiyuki Horio Sapporo Medical University

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