Toshiyoshi Fujiwara

Overview

Best Publications

• Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression.

  L B Owen-Schaub;W Zhang;J C Cusack;L S Angelo

  1080
  Citations

• Induction of Chemosensitivity in Human Lung Cancer Cells in Vivo by Adenovirus-mediated Transfer of the Wild-Type p53 Gene

  Toshiyoshi Fujiwara;Elizabeth A. Grimm;Tapas Mukhopadhyay;Wei Wei Zhang

  684
  Citations

• Prevention of Acute Liver Failure in Rats with Reversibly Immortalized Human Hepatocytes

  Naoya Kobayashi;Toshiyoshi Fujiwara;Karen A. Westerman;Yusuke Inoue

  483
  Citations

• Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers

  Satoru Kyo;Masahiro Takakura;Toshiyoshi Fujiwara;Masaki Inoue

  473
  Citations

• Circular RNA ciRS-7—A Promising Prognostic Biomarker and a Potential Therapeutic Target in Colorectal Cancer

  Wenhao Weng;Wenhao Weng;Qing Wei;Shusuke Toden;Kazuhiro Yoshida

  440
  Citations

• Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancer.

  Michael Bouvet;Lee M. Ellis;Masahiko Nishizaki;Toshiyoshi Fujiwara

  373
  Citations

• Evidence for p53-Mediated Modulation of Neuronal Viability

  Hong Xiang;Daryl W. Hochman;Hideyuki Saya;Toshiyoshi Fujiwara

  360
  Citations

• Anvendelse av villtype p53-protein eller p53-kodende sekvens for fremstilling av et medikament for behandling av kreft.

  Zhang Wei-Wei;Roth Jack A;Fujiwara Toshiyoshi;Grimm Elizabeth A

  331
  Citations

• A Phase I Study of Telomerase-specific Replication Competent Oncolytic Adenovirus (Telomelysin) for Various Solid Tumors

  John Nemunaitis;Alex W. Tong;Michael Nemunaitis;Neil Senzer

  328
  Citations

• Telomerase-specific replication-selective virotherapy for human cancer.

  Takeshi Kawashima;Shunsuke Kagawa;Naoya Kobayashi;Yoshiko Shirakiya

  328
  Citations

• A Retroviral Wild-type p53 Expression Vector Penetrates Human Lung Cancer Spheroids and Inhibits Growth by Inducing Apoptosis

  Toshiyoshi Fujiwara;Elizabeth A. Grimm;Tapas Mukhopadhyay;De Wei Cai

  312
  Citations

• Therapeutic Effect of a Retroviral Wild-Type p53 Expression Vector in an Orthotopic Lung Cancer Model

  Toshiyoshi Fujiwara;De Wei Cai;Renee N. Georges;Tapas Mukhopadhyay

  303
  Citations

• Cancer-Associated Fibroblasts Affect Intratumoral CD8+ and FoxP3+ T Cells Via IL6 in the Tumor Microenvironment

  Takuya Kato;Kazuhiro Noma;Toshiaki Ohara;Hajime Kashima

  276
  Citations

• Heparanase Expression Correlates with Invasion and Poor Prognosis in Gastric Cancers

  Munenori Takaoka;Yoshio Naomoto;Takaomi Ohkawa;Hirokazu Uetsuka

  272
  Citations

• In vivo imaging of lymph node metastasis with telomerase-specific replication-selective adenovirus

  Hiroyuki Kishimoto;Toru Kojima;Yuichi Watanabe;Shunsuke Kagawa

  227
  Citations

• Overexpression of the wild-type p53 gene inhibits NF-κB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells

  Jianghua Shao;Toshiyoshi Fujiwara;Yoshihiko Kadowaki;Takuya Fukazawa

  195
  Citations

• Transcriptional blockade induces p53-dependent apoptosis associated with translocation of p53 to mitochondria.

  Yoshimi Arima;Masayuki Nitta;Shinji Kuninaka;Dongwei Zhang

  191
  Citations

• Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells.

  Takuya Fukazawa;Toshiyoshi Fujiwara;Futoshi Uno;Fuminori Teraishi

  190
  Citations

• Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer.

  Wenhao Weng;Wenhao Weng;Na Liu;Yuji Toiyama;Masato Kusunoki

  184
  Citations

• Stable Expression of the Wild-Type p53 Gene in Human Lung Cancer Cells after Retrovirus-Mediated Gene Transfer

  De Wei Cai;Tapas Mukhopadhyay;Yongjian Liu;Toshiyoshi Fujiwara

  181
  Citations