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Chemistry

D-Index
54
Citations
12221
World Ranking
12500
National Ranking
706

Overview

Ian L. Megson is affiliated with the University of the Highlands and Islands in the United Kingdom. Their research primarily focuses on the field of Medicine, covering a total of 36 publications, with notable subfields including Biomedical Engineering, Cardiology and Cardiovascular Medicine, Pulmonary and Respiratory Medicine, Physiology, and Surgery.

The scientist has contributed to several main topics of work, particularly:

  • Graphene and Nanomaterials Applications
  • Nanoplatforms for cancer theranostics
  • Adipose Tissue and Metabolism
  • Renal and Vascular Pathologies
  • Acute Kidney Injury Research
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19

Notable papers authored include:

  • Why Is COVID-19 More Severe in Patients With Diabetes? The Role of Angiotensin-Converting Enzyme 2, Endothelial Dysfunction and the Immunoinflammatory System, 2021, Frontiers in Cardiovascular Medicine
  • First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses, 2024, Nature Nanotechnology
  • Measurement of Heart Rate Using the Polar OH1 and Fitbit Charge 3 Wearable Devices in Healthy Adults During Light, Moderate, Vigorous, and Sprint-Based Exercise: Validation Study, 2021, JMIR mhealth and uhealth
  • Exosomal Composition, Biogenesis and Profiling Using Point-of-Care Diagnostics-Implications for Cardiovascular Disease, 2022, Frontiers in Cell and Developmental Biology
  • Antibacterial efficacy from NO-releasing MOF-polymer films, 2020, Materials Advances

The frequent coauthors collaborating with Ian L. Megson are:

  • Andrew T. Treweeke
  • Kirsty Hickson
  • David J. Muggeridge
  • David P. Macfarlane
  • Khuram Raja

Publications have appeared across a range of venues including:

  • Frontiers in Cardiovascular Medicine
  • Nature Nanotechnology
  • JMIR mhealth and uhealth
  • Frontiers in Cell and Developmental Biology
  • Materials Advances

Best Publications

  • Existing and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits.

    Gordon F Rushworth;Ian L Megson

  • Recent developments in nitric oxide donor drugs

    M R Miller;I L Megson

  • High-capacity hydrogen and nitric oxide adsorption and storage in a metal-organic framework

    Bo Xiao;Paul S. Wheatley;Xuebo Zhao;Ashleigh J. Fletcher

  • Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells.

    Aruna Kode;Saravanan Rajendrasozhan;Samuel Caito;Se-Ran Yang

  • Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity.

    Saibal K Biswas;Danny McClure;Luis A Jimenez;Ian L Megson

  • Exceptional behavior over the whole adsorption-storage-delivery cycle for NO in porous metal organic frameworks.

    Alistair C McKinlay;Bo Xiao;David S Wragg;Paul S Wheatley

  • Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes

    Wan-Seob Cho;Rodger Duffin;Sarah E M Howie;Chris J Scotton

  • Non-heme iron nitrosyls in biology

    Anthony R. Butler;Ian L. Megson

  • Metal Oxide Nanoparticles Induce Unique Inflammatory Footprints in the Lung: Important Implications for Nanoparticle Testing

    Wan-Seob Cho;Rodger Duffin;Craig A Poland;Sarah E M Howie

  • ZETA POTENTIAL AND SOLUBILITY TO TOXIC IONS AS MECHANISMS OF LUNG INFLAMMATION CAUSED BY METAL/METAL-OXIDE NANOPARTICLES

    Wan-Seob Cho;Rodger Duffin;Frank Thielbeer;Mark Bradley

  • Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs.

    Wan-Seob Cho;Rodger Duffin;Craig A. Poland;Albert Duschl

  • NO-releasing zeolites and their antithrombotic properties.

    Paul S Wheatley;Anthony R Butler;Michael S Crane;Sarah Fox

  • Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: key role for TNF-α

    Sylwia Michlewska;Ian Dransfield;Ian L. Megson;Adriano G. Rossi

  • Endothelial dysfunction: from molecular mechanisms to measurement, clinical implications, and therapeutic opportunities.

    Michelle Le Brocq;Stephen J. Leslie;Philip Milliken;Ian L. Megson

  • Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2.

    Koremu K. Meja;Saravanan Rajendrasozhan;David Adenuga;Saibal K. Biswas

  • DIFFUSION OF NITRIC OXIDE AND SCAVENGING BY BLOOD IN THE VASCULATURE

    Anthony R. Butler;Ian L. Megson;Patrick G. Wright

  • Nitric oxide: a key regulator of myeloid inflammatory cell apoptosis

    E.L Taylor;I. L. Megson;Christopher Haslett;Adriano G Rossi

  • Direct impairment of vascular function by diesel exhaust particulate through reduced bioavailability of endothelium-derived nitric oxide induced by superoxide free radicals.

    Mark R Miller;Stephen J Borthwick;Catherine A Shaw;Steven G McLean

  • Ruthenium complexes as nitric oxide scavengers: a potential therapeutic approach to nitric oxide‐mediated diseases

    S. P. Fricker;Elizabeth Slade;N. A. Powell;O. J. Vaughan

  • Bioactive polyphenols and cardiovascular disease: chemical antagonists, pharmacological agents or xenobiotics that drive an adaptive response?

    Katarzyna Goszcz;Garry G Duthie;Derek Stewart;Derek Stewart;Stephen J Leslie;Stephen J Leslie

  • Iron‐sulphur cluster nitrosyls, a novel class of nitric oxide generator: mechanism of vasodilator action on rat isolated tail artery

    F.W. Flitney;I.L. Megson;D.E. Flitney;A.R. Butler

Frequent Co-Authors

David J. Webb
David J. Webb University of Edinburgh
Adriano G. Rossi
Adriano G. Rossi University of Edinburgh
David E. Newby
David E. Newby University of Edinburgh
Russell E. Morris
Russell E. Morris University of St Andrews
Jun Wei
Jun Wei The University of Texas MD Anderson Cancer Center
Ken Donaldson
Ken Donaldson University of Edinburgh
Derek Stewart
Derek Stewart James Hutton Institute
William MacNee
William MacNee University of Edinburgh
Mark Bradley
Mark Bradley University of Edinburgh
Nicholas L. Mills
Nicholas L. Mills University of Edinburgh

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