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Medicine

D-Index
140
Citations
79893
World Ranking
1684
National Ranking
973

Research.com Recognitions

  • 2020 - Distinguished Scientist Award, American Heart Association
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Mark T. Gladwin is affiliated with the University of Pittsburgh in the United States. The researcher's work spans a considerable number of publications primarily in the fields of medicine, biochemistry, genetics, and molecular biology.

Their recent notable papers include:

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program (2021, Nature)
  • Research Priorities for Heart Failure With Preserved Ejection Fraction (2020, Circulation)
  • Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity (2020, Haematologica)
  • Opioid-Associated Out-of-Hospital Cardiac Arrest: Distinctive Clinical Features and Implications for Health Care and Public Responses: A Scientific Statement From the American Heart Association (2021, Circulation)
  • Home Nitric Oxide Therapy for COVID-19 (2020, American Journal of Respiratory and Critical Care Medicine)

The frequent co-authors collaborating with this researcher include:

  • Mehdi Nouraie
  • Victor R. Gordeuk
  • Jesús Tejero
  • Anthony W. DeMartino
  • Yingze Zhang

Common venues for publication reflect the breadth of their work and include:

  • Blood
  • Circulation
  • American Journal of Respiratory and Critical Care Medicine
  • American Journal of Hematology
  • bioRxiv (Cold Spring Harbor Laboratory)

Their primary research areas cover several main fields of study:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these, subfields of study are:

  • Genetics
  • Hematology
  • Molecular Biology
  • Physiology
  • Pulmonary and Respiratory Medicine

The main topics of their work further specify interests and expertise as:

  • Hemoglobinopathies and Related Disorders
  • Iron Metabolism and Disorders
  • Hemoglobin Structure and Function
  • Pulmonary Hypertension Research and Treatments
  • Neonatal Health and Biochemistry
  • Blood Groups and Transfusion
  • Erythrocyte Function and Pathophysiology

Mark T. Gladwin has received recognition including the Distinguished Scientist Award from the American Heart Association in 2020 and is a member of the Association of American Physicians.

Best Publications

  • The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics

    Jon O. Lundberg;Eddie Weitzberg;Mark T. Gladwin

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation.

    Kenyatta Cosby;Kristine S Partovi;Jack H Crawford;Rakesh P Patel

  • The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease.

    Russell P. Rother;Leonard Bell;Peter Hillmen;Mark T. Gladwin

  • Pulmonary hypertension as a risk factor for death in patients with sickle cell disease

    Mark T. Gladwin;Vandana Sachdev;Maria L. Jison;Yukitaka Shizukuda

  • Sickle Cell Disease

    David C Rees;Thomas N Williams;Thomas N Williams;Mark T Gladwin

  • Right Ventricular Function and Failure Report of a National Heart, Lung, and Blood Institute Working Group on Cellular and Molecular Mechanisms of Right Heart Failure

    Norbert F. Voelkel;Robert A. Quaife;Leslie A. Leinwand;Robyn J. Barst

  • Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease.

    Christopher D Reiter;Xunde Wang;Jose E Tanus-Santos;Neil Hogg

  • Deconstructing sickle cell disease: Reappraisal of the role of hemolysis in the development of clinical subphenotypes

    Gregory J. Kato;Mark T. Gladwin;Martin H. Steinberg

  • Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease.

    Claudia R. Morris;Gregory J. Kato;Mirjana Poljakovic;Xunde Wang

  • Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease

    Gregory J Kato;Gregory J Kato;Gregory J Kato;Vicki R McGowan;Vicki R McGowan;Vicki R McGowan;Roberto F Machado;Roberto F Machado;Roberto F Machado;Jane A Little;Jane A Little;Jane A Little

  • Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver

    Mark R. Duranski;James J.M. Greer;Andre Dejam;Sathya Jaganmohan

  • Nitrate and nitrite in biology, nutrition and therapeutics

    Jon O Lundberg;Mark T Gladwin;Amrita Ahluwalia;Nigel Benjamin

  • The emerging biology of the nitrite anion

    Mark T Gladwin;Alan N Schechter;Daniel B Kim-Shapiro;Rakesh P Patel

  • Carbon Monoxide Poisoning: Pathogenesis, Management, and Future Directions of Therapy

    Jason J. Rose;Ling Wang;Qinzi Xu;Charles F. McTiernan

  • Intravascular hemolysis and the pathophysiology of sickle cell disease

    Gregory J. Kato;Martin H. Steinberg;Mark T. Gladwin

  • Deoxymyoglobin is a Nitrite Reductase That Generates Nitric Oxide and Regulates Mitochondrial Respiration

    Sruti Shiva;Zhi Huang;Rozalina Grubina;Junhui Sun

  • Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion.

    Chenell Donadee;Nicolaas J.H. Raat;Tamir Kanias;Jesús Tejero

  • Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

    Sruti Shiva;Michael N. Sack;James J. Greer;Mark Duranski

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

Frequent Co-Authors

Gregory J. Kato
Gregory J. Kato CSL Behring
Victor R. Gordeuk
Victor R. Gordeuk University of Illinois at Chicago
Sruti Shiva
Sruti Shiva University of Pittsburgh
Alan N. Schechter
Alan N. Schechter National Institute of Diabetes and Digestive and Kidney Diseases
Neil Hogg
Neil Hogg Medical College of Wisconsin
Martin H. Steinberg
Martin H. Steinberg Boston University
Janet S. Lee
Janet S. Lee University of Pittsburgh
Allison E. Ashley-Koch
Allison E. Ashley-Koch Duke University
James H. Shelhamer
James H. Shelhamer National Institutes of Health
Robyn J. Barst
Robyn J. Barst Columbia University

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