D-Index & Metrics Best Publications
Biology and Biochemistry
France
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 69 Citations 13,085 245 World Ranking 3902 National Ranking 115
Biology and Biochemistry D-index 73 Citations 15,959 272 World Ranking 3784 National Ranking 93

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in France Leader Award

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • DNA
  • Gene

His primary areas of investigation include Transfer RNA, Biochemistry, RNA, Aminoacylation and Stereochemistry. His Transfer RNA research is included under the broader classification of Genetics. His Biochemistry research focuses on Molecular biology and how it relates to ATP synthase and Single nucleotide mutation.

His RNA research is multidisciplinary, relying on both Mitochondrion and Protein folding. His Aminoacylation research focuses on subjects like Amino Acyl-tRNA Synthetases, which are linked to Genetic code and Valine—tRNA ligase. His Stereochemistry research includes elements of Cleavage, Phosphodiester bond and Binding site.

His most cited work include:

  • Universal rules and idiosyncratic features in tRNA identity (606 citations)
  • An operational RNA code for amino acids and possible relationship to genetic code. (329 citations)
  • Crystal structure of yeast tRNAAsp. (246 citations)

What are the main themes of his work throughout his whole career to date?

Richard Giegé focuses on Transfer RNA, Biochemistry, RNA, Aminoacylation and Yeast. His Transfer RNA research is multidisciplinary, incorporating perspectives in Amino acid, Stereochemistry and Nucleotide. His work on Turnip yellow mosaic virus, Brome mosaic virus, RNA-dependent RNA polymerase and Pseudoknot as part of general RNA research is frequently linked to T7 RNA polymerase, bridging the gap between disciplines.

His biological study spans a wide range of topics, including Mutation, Molecular biology, Transfer RNA Aminoacylation and Footprinting. His Yeast research incorporates themes from Crystallography, Dimer and Aspartyl-tRNA synthetase. His research in Aminoacyl tRNA synthetase intersects with topics in Translation and T arm.

He most often published in these fields:

  • Transfer RNA (64.39%)
  • Biochemistry (51.80%)
  • RNA (28.42%)

What were the highlights of his more recent work (between 2000-2013)?

  • Transfer RNA (64.39%)
  • Biochemistry (51.80%)
  • Crystallography (20.86%)

In recent papers he was focusing on the following fields of study:

Richard Giegé mainly focuses on Transfer RNA, Biochemistry, Crystallography, Genetics and Crystallization. His study on Transfer RNA is covered under RNA. His Crystallography research integrates issues from Thermus thermophilus and Agarose.

His research investigates the connection between Crystallization and topics such as Nucleation that intersect with problems in Nanotechnology. His Aminoacylation study which covers Saccharomyces cerevisiae that intersects with Sequence alignment. His work in Aminoacyl tRNA synthetase covers topics such as T arm which are related to areas like RNase P.

Between 2000 and 2013, his most popular works were:

  • Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. (102 citations)
  • Toward a more complete view of tRNA biology (90 citations)
  • A historical perspective on protein crystallization from 1840 to the present day (79 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • DNA
  • Gene

His scientific interests lie mostly in Transfer RNA, Genetics, Biochemistry, RNA and Aminoacylation. Particularly relevant to Aminoacyl tRNA synthetase is his body of work in Transfer RNA. In the subject of general Genetics, his work in Mitochondrion, Genetic code, Eukaryotic translation and Glutamate—tRNA ligase is often linked to Histone methylation, thereby combining diverse domains of study.

His studies in RNA integrate themes in fields like Amino acid, Methanococcus, Neurospora crassa and Computational biology. In his research on the topic of Aminoacylation, Elongation factor and Pseudoknot is strongly related with Function. His research investigates the connection between T arm and topics such as Nucleic acid that intersect with issues in Crystallography.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Universal rules and idiosyncratic features in tRNA identity

Richard Giegé;Marie Sissler;Catherine Florentz.
Nucleic Acids Research (1998)

1010 Citations

An operational RNA code for amino acids and possible relationship to genetic code.

Paul Schimmel;Richard Giege;Dino Moras;Shigeyuki Yokoyama.
Proceedings of the National Academy of Sciences of the United States of America (1993)

484 Citations

Crystal structure of yeast tRNAAsp.

D Moras;M B Comarmond;J Fischer;R Weiss.
Nature (1980)

382 Citations

Search for characteristic structural features of mammalian mitochondrial tRNAs.

Mark Helm;Hervé Brulé;Dagmar Friede;Richard Giegé.
RNA (2000)

368 Citations

tRNA structure and aminoacylation efficiency.

Richard Giegé;Joseph D. Puglisi;Catherine Florentz.
Progress in Nucleic Acid Research and Molecular Biology (1993)

288 Citations

The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA

Mark Helm;Hervé Brulé;Hervé Brulé;Françoise Degoul;Claude Cepanec.
Nucleic Acids Research (1998)

273 Citations

A Watson-Crick base-pair-disrupting methyl group (m1A9) is sufficient for cloverleaf folding of human mitochondrial tRNALys.

Mark Helm;Richard Giegé;Catherine Florentz.
Biochemistry (1999)

269 Citations

Relaxation of a transfer RNA specificity by removal of modified nucleotides.

Véronique Perret;Angela Garcia;Henri Grosjean;Jean-Pierre Ebel.
Nature (1990)

263 Citations

Factors determining the specificity of the tRNA aminoacylation reaction. Non-absolute specificity of tRNA-aminoacyl-tRNA synthetase recognition and particular importance of the maximal velocity.

J.P. Ebel;R. Giegé;J. Bonnet;D. Kern.
Biochimie (1973)

248 Citations

Identity elements for specific aminoacylation of yeast tRNA(Asp) by cognate aspartyl-tRNA synthetase.

Joern Pütz;Joseph D. Puglisi;Catherine Florentz;Richard Giegé.
Science (1991)

207 Citations

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