2023 - Research.com Biology and Biochemistry in France Leader Award
Member of the European Molecular Biology Organization (EMBO)
His primary areas of investigation include Transfer RNA, Biochemistry, RNA, Aminoacylation and Stereochemistry. His Transfer RNA research is included under the broader classification of Genetics. His Biochemistry research focuses on Molecular biology and how it relates to ATP synthase and Single nucleotide mutation.
His RNA research is multidisciplinary, relying on both Mitochondrion and Protein folding. His Aminoacylation research focuses on subjects like Amino Acyl-tRNA Synthetases, which are linked to Genetic code and Valine—tRNA ligase. His Stereochemistry research includes elements of Cleavage, Phosphodiester bond and Binding site.
Richard Giegé focuses on Transfer RNA, Biochemistry, RNA, Aminoacylation and Yeast. His Transfer RNA research is multidisciplinary, incorporating perspectives in Amino acid, Stereochemistry and Nucleotide. His work on Turnip yellow mosaic virus, Brome mosaic virus, RNA-dependent RNA polymerase and Pseudoknot as part of general RNA research is frequently linked to T7 RNA polymerase, bridging the gap between disciplines.
His biological study spans a wide range of topics, including Mutation, Molecular biology, Transfer RNA Aminoacylation and Footprinting. His Yeast research incorporates themes from Crystallography, Dimer and Aspartyl-tRNA synthetase. His research in Aminoacyl tRNA synthetase intersects with topics in Translation and T arm.
Richard Giegé mainly focuses on Transfer RNA, Biochemistry, Crystallography, Genetics and Crystallization. His study on Transfer RNA is covered under RNA. His Crystallography research integrates issues from Thermus thermophilus and Agarose.
His research investigates the connection between Crystallization and topics such as Nucleation that intersect with problems in Nanotechnology. His Aminoacylation study which covers Saccharomyces cerevisiae that intersects with Sequence alignment. His work in Aminoacyl tRNA synthetase covers topics such as T arm which are related to areas like RNase P.
His scientific interests lie mostly in Transfer RNA, Genetics, Biochemistry, RNA and Aminoacylation. Particularly relevant to Aminoacyl tRNA synthetase is his body of work in Transfer RNA. In the subject of general Genetics, his work in Mitochondrion, Genetic code, Eukaryotic translation and Glutamate—tRNA ligase is often linked to Histone methylation, thereby combining diverse domains of study.
His studies in RNA integrate themes in fields like Amino acid, Methanococcus, Neurospora crassa and Computational biology. In his research on the topic of Aminoacylation, Elongation factor and Pseudoknot is strongly related with Function. His research investigates the connection between T arm and topics such as Nucleic acid that intersect with issues in Crystallography.
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Universal rules and idiosyncratic features in tRNA identity
Richard Giegé;Marie Sissler;Catherine Florentz.
Nucleic Acids Research (1998)
An operational RNA code for amino acids and possible relationship to genetic code.
Paul Schimmel;Richard Giege;Dino Moras;Shigeyuki Yokoyama.
Proceedings of the National Academy of Sciences of the United States of America (1993)
Crystal structure of yeast tRNAAsp.
D Moras;M B Comarmond;J Fischer;R Weiss.
Search for characteristic structural features of mammalian mitochondrial tRNAs.
Mark Helm;Hervé Brulé;Dagmar Friede;Richard Giegé.
tRNA structure and aminoacylation efficiency.
Richard Giegé;Joseph D. Puglisi;Catherine Florentz.
Progress in Nucleic Acid Research and Molecular Biology (1993)
The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA
Mark Helm;Hervé Brulé;Hervé Brulé;Françoise Degoul;Claude Cepanec.
Nucleic Acids Research (1998)
A Watson-Crick base-pair-disrupting methyl group (m1A9) is sufficient for cloverleaf folding of human mitochondrial tRNALys.
Mark Helm;Richard Giegé;Catherine Florentz.
Relaxation of a transfer RNA specificity by removal of modified nucleotides.
Véronique Perret;Angela Garcia;Henri Grosjean;Jean-Pierre Ebel.
Factors determining the specificity of the tRNA aminoacylation reaction. Non-absolute specificity of tRNA-aminoacyl-tRNA synthetase recognition and particular importance of the maximal velocity.
J.P. Ebel;R. Giegé;J. Bonnet;D. Kern.
Identity elements for specific aminoacylation of yeast tRNA(Asp) by cognate aspartyl-tRNA synthetase.
Joern Pütz;Joseph D. Puglisi;Catherine Florentz;Richard Giegé.
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