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Biology and Biochemistry

D-Index
51
Citations
22822
World Ranking
16914
National Ranking
597

Overview

Albert Descoteaux is affiliated with the Institut National de la Recherche Scientifique in Canada. Their research primarily focuses on the field of Medicine, with significant contributions spanning Public Health, Environmental and Occupational Health, Epidemiology, Molecular Biology, Parasitology, and Immunology.

The scientist has a research emphasis on several main topics, including:

  • Research on Leishmaniasis Studies
  • Trypanosoma species research and implications
  • Parasites and Host Interactions
  • Eosinophilic Disorders and Syndromes
  • Cellular transport and secretion
  • Lipid Membrane Structure and Behavior
  • Viral Infections and Vectors

Notable recent publications by Albert Descoteaux include:

  • Translational profiling of macrophages infected with Leishmania donovani identifies mTOR- and eIF4A-sensitive immune-related transcripts (2020) in PLoS Pathogens
  • Immunomodulatory Properties of Leishmania Extracellular Vesicles During Host-Parasite Interaction: Differential Activation of TLRs and NF-κB Translocation by Dermotropic and Viscerotropic Species (2020) in Frontiers in Cellular and Infection Microbiology
  • Revisiting Leishmania GP63 host cell targets reveals a limited spectrum of substrates (2022) in PLoS Pathogens
  • Autophagy in protists and their hosts: When, how and why? (2023) in Autophagy Reports
  • Study on the Occurrence of Genetic Exchange Among Parasites of the Leishmania mexicana Complex (2020) in Frontiers in Cellular and Infection Microbiology

The primary venues where Descoteaux's work has been published include:

  • Frontiers in Cellular and Infection Microbiology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • PLoS Pathogens
  • Autophagy Reports

Albert Descoteaux collaborates frequently with a number of researchers, including:

  • Guillermo Arango Duque
  • Christine Matte
  • Valéria M. Borges
  • Simona Stäger
  • Maritza Jaramillo

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Macrophage cytokines: involvement in immunity and infectious diseases.

    Guillermo Arango Duque;Albert Descoteaux

  • The lipophosphoglycan of Leishmania parasites

    Salvatore J. Turco;Albert Descoteaux

  • Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases

    Marina Tiemi Shio;Stephanie C. Eisenbarth;Myriam Savaria;Adrien F. Vinet

  • Inhibition of Phagolysosomal Biogenesis by the Leishmania Lipophosphoglycan

    Michel Desjardins;Albert Descoteaux

  • Cyclooxygenase-2 Expression in Macrophages: Modulation by Protein Kinase C-α

    Mélanie Giroux;Albert Descoteaux

  • Glycoconjugates in Leishmania infectivity.

    Albert Descoteaux;Salvatore J Turco

  • Protein Kinase C-ζ Regulates Transcription of the Matrix Metalloproteinase-9 Gene Induced by IL-1 and TNF-α in Glioma Cells via NF-κB

    Pierre Olivier Estève;Éric Chicoine;Olivier Robledo;Fawzi Aoudjit

  • RNA interference reveals a role for TLR2 and TLR3 in the recognition of Leishmania donovani promastigotes by interferon–γ‐primed macrophages

    Jean-Frédéric Flandin;Frédéric Chano;Albert Descoteaux

  • Leishmania donovani promastigotes evade the antimicrobial activity of neutrophil extracellular traps.

    Christelle Gabriel;W. Robert McMaster;Denis Girard;Albert Descoteaux

  • Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages.

    S. Duclos;R. Diez;J. Garin;B. Papadopoulou

  • Leishmania and the macrophage: a multifaceted interaction.

    Maria Podinovskaia;Albert Descoteaux

  • Leishmania donovani lipophosphoglycan blocks NADPH oxidase assembly at the phagosome membrane

    Robert Lodge;Tamsir O. Diallo;Albert Descoteaux

  • Leishmania donovani promastigotes evade the activation of mitogen‐activated protein kinases p38, c‐Jun N‐terminal kinase, and extracellular signal‐regulated kinase‐1/2 during infection of naive macrophages

    Charles Privé;Albert Descoteaux

  • Impaired recruitment of the small GTPase rab7 correlates with the inhibition of phagosome maturation by Leishmania donovani promastigotes.

    Sandra Scianimanico;Marcel Desrosiers;Jean‐François Dermine;Stéphane Méresse

  • Inhibition of macrophage protein kinase C-mediated protein phosphorylation by Leishmania donovani lipophosphoglycan.

    A Descoteaux;G Matlashewski;S J Turco

  • A specialized pathway affecting virulence glycoconjugates of Leishmania.

    Albert Descoteaux;Ya Luo;Salvatore J. Turco;Stephen M. Beverley

  • Leishmania promastigotes: building a safe niche within macrophages.

    Neda Moradin;Albert Descoteaux

  • Isolation of virulence genes directing surface glycosyl-phosphatidylinositol synthesis by functional complementation of Leishmania.

    Kathleen A. Ryan;Levi A. Garraway;Albert Descoteaux;Salvatore J. Turco

  • Leishmania donovani lipophosphoglycan selectively inhibits signal transduction in macrophages.

    A Descoteaux;S J Turco;D L Sacks;G Matlashewski

Frequent Co-Authors

Salvatore J. Turco
Salvatore J. Turco University of Kentucky
Mitsunori Fukuda
Mitsunori Fukuda Tohoku University
Michel Desjardins
Michel Desjardins University of Montreal
Martin Olivier
Martin Olivier McGill University
Stephen M. Beverley
Stephen M. Beverley Washington University in St. Louis
Karl-Eric Magnusson
Karl-Eric Magnusson Linköping University
Greg Matlashewski
Greg Matlashewski McGill University
Fayyaz S. Sutterwala
Fayyaz S. Sutterwala Cedars-Sinai Medical Center
Richard A. Flavell
Richard A. Flavell Yale University

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