Ruili Huang

Overview

Best Publications

• Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

  Miao Xu;Emily M. Lee;Zhexing Wen;Yichen Cheng

  692
  Citations

• The NCGC Pharmaceutical Collection: A Comprehensive Resource of Clinically Approved Drugs Enabling Repurposing and Chemical Genomics

  Ruili Huang;Noel Southall;Yuhong Wang;Adam Yasgar

  440
  Citations

• CERAPP: Collaborative Estrogen Receptor Activity Prediction Project

  Kamel Mansouri;Ahmed Abdelaziz;Aleksandra Rybacka;Alessandra Roncaglioni

  381
  Citations

• Identification of Known Drugs that Act as Inhibitors of NF-κB Signaling and their Mechanism of Action

  Susanne C. Miller;Ruili Huang;Srilatha Sakamuru;Sunita J. Shukla

  313
  Citations

• The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform

  Sunita J. Shukla;Ruili Huang;Christopher P. Austin;Menghang Xia

  308
  Citations

• The NCATS BioPlanet - An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics.

  Ruili Huang;Ivan Grishagin;Yuhong Wang;Tongan Zhao

  299
  Citations

• Compound cytotoxicity profiling using quantitative high-throughput screening.

  Menghang Xia;Ruili Huang;Kristine L. Witt;Noel Southall

  291
  Citations

• Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High Throughput Screening Assays for the Estrogen Receptor

  Richard S. Judson;Felicia Maria Magpantay;Vijay Chickarmane;Cymra Haskell

  287
  Citations

• Fluorescence Spectroscopic Profiling of Compound Libraries

  Anton Simeonov;Ajit Jadhav;Craig J. Thomas;Yuhong Wang

  281
  Citations

• Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

  Richard Judson;Keith Houck;Matt Martin;Ann M. Richard

  246
  Citations

• The Tox21 robotic platform for the assessment of environmental chemicals--from vision to reality.

  Matias S. Attene-Ramos;Nicole Miller;Ruili Huang;Sam Michael

  243
  Citations

• Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization

  Ruili Huang;Menghang Xia;Srilatha Sakamuru;Jinghua Zhao

  231
  Citations

• Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction

  Zhong Li;Matthew Brecher;Yong Qiang Deng;Jing Zhang

  217
  Citations

• Analysis of Eight Oil Spill Dispersants Using Rapid, In Vitro Tests for Endocrine and Other Biological Activity

  Richard S. Judson;Matthew T. Martin;David M. Reif;Keith A. Houck

  213
  Citations

• Chemical genomics profiling of environmental chemical modulation of human nuclear receptors.

  Ruili Huang;Menghang Xia;Ming-Hsuang Cho;Srilatha Sakamuru

  211
  Citations

• Bisphenol A affects androgen receptor function via multiple mechanisms.

  Christina Teng;Bonnie Goodwin;Keith Shockley;Menghang Xia

  208
  Citations

• Comprehensive Characterization of Cytochrome P450 Isozyme Selectivity across Chemical Libraries

  Henrike Veith;Noel Southall;Ruili Huang;Tim James

  205
  Citations

• Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential

  Matias S. Attene-Ramos;Ruili Huang;Sam Michael;Kristine L. Witt

  196
  Citations

• The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology.

  Ann M Richard;Ruili Huang;Suramya Waidyanatha;Paul Shinn

  195
  Citations

• Development and Validation of a Computational Model for Androgen Receptor Activity

  Nicole C. Kleinstreuer;Patricia Ceger;Eric D. Watt;Matthew Martin

  193
  Citations