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Biology and Biochemistry

D-Index
71
Citations
19279
World Ranking
6595
National Ranking
3072

Overview

Min Shen is affiliated with the National Institutes of Health in the United States.

Their research spans primarily the fields of Medicine as well as Biochemistry, Genetics and Molecular Biology. Within these broader disciplines, they focus on several subfields including Molecular Biology, Infectious Diseases, Computational Theory and Mathematics, Oncology, and Epidemiology.

The main topics in Min Shen's work cover areas such as Computational Drug Discovery Methods, SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, Mosquito-borne diseases and control, Lung Cancer Research Studies, SARS-CoV-2 detection and testing, and Viral Infections and Outbreaks Research.

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • ACS Pharmacology & Translational Science
  • Journal of Medicinal Chemistry
  • Cancer Research
  • Journal of Chemical Information and Modeling

Regular collaborators in Shen's research include:

  • Matthew D. Hall
  • Wei Zheng
  • Catherine Z. Chen
  • Anton Simeonov
  • Paul Shinn

Notable recent papers authored or coauthored by Min Shen are:

  • "Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19" (2020), published in ACS Central Science
  • "Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro" (2020), published in Cell Discovery
  • "Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-Throughput Screening" (2020), published in ACS Pharmacology & Translational Science
  • "An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19" (2020), published in ACS Pharmacology & Translational Science
  • "Identifying SARS-CoV-2 Entry Inhibitors through Drug Repurposing Screens of SARS-S and MERS-S Pseudotyped Particles" (2020), published in ACS Pharmacology & Translational Science

Best Publications

  • Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

    Dimitrios Anastasiou;Dimitrios Anastasiou;George Poulogiannis;George Poulogiannis;John M. Asara;John M. Asara;Matthew B. Boxer

  • Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

    Jian-Wen Han;Jian-Wen Han;Hou-Feng Zheng;Hou-Feng Zheng;Yong Cui;Yong Cui;Liang-Dan Sun;Liang-Dan Sun

  • Genomewide association study of leprosy.

    Fu-Ren Zhang;Wei Huang;Shu-Min Chen;Liang-Dan Sun

  • Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19

    Richard T. Eastman;Jacob S. Roth;Jacob S. Roth;Kyle R. Brimacombe;Anton Simeonov

  • Hematotoxicity in Workers Exposed to Low Levels of Benzene

    Qing Lan;Luoping Zhang;Guilan Li;Roel Vermeulen

  • Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.

    Dimitrios Anastasiou;Yimin Yu;William James Israelsen;Jian-Kang Jiang

  • A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

    Michael E. Pacold;Kyle R. Brimacombe;Sze Ham Chan;Jason M. Rohde

  • Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.

    Fadi J. Najm;Mayur Madhavan;Anita Zaremba;Elizabeth Shick

  • Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors

    Anju Singh;Sreedhar Venkannagari;Kyu H. Oh;Ya Qin Zhang

  • Shortened Telomere Length Is Associated with Increased Risk of Cancer: A Meta-Analysis

    Hongxia Ma;Hongxia Ma;Ziyuan Zhou;Sheng Wei;Zhensheng Liu

  • Occupational Exposure to Formaldehyde, Hematotoxicity, and Leukemia-Specific Chromosome Changes in Cultured Myeloid Progenitor Cells

    Luoping Zhang;Xiaojiang Tang;Nathaniel Rothman;Roel Vermeulen

  • Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia

    Warren Fiskus;Nakhle Saba;Min Shen;Mondana Ghias

  • Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC

    Cheng Quan;Yun-Qing Ren;Lei-Hong Xiang;Liang-Dan Sun

  • Mitochondrial DNA copy number and lung cancer risk in a prospective cohort study

    H. Dean Hosgood;Chin San Liu;Nathaniel Rothman;Stephanie J. Weinstein

  • Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma

    Qing Lan;Tongzhang Zheng;Nathaniel Rothman;Yawei Zhang

  • Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro

    Qi Zhang;Catherine Zhengzheng Chen;Manju Swaroop;Miao Xu

  • Polymorphisms of the DNA repair genes XRCC1, XRCC3, XPD, interaction with environmental exposures, and bladder cancer risk in a case-control study in northern Italy.

    Min Shen;Rayjean J. Hung;Paul Brennan;Christian Malaveille

  • The 5p15.33 Locus Is Associated with Risk of Lung Adenocarcinoma in Never-Smoking Females in Asia

    Chao Agnes Hsiung;Qing Lan;Yun Chul Hong;Chien Jen Chen;Chien Jen Chen

  • Comprehensive Characterization of Cytochrome P450 Isozyme Selectivity across Chemical Libraries

    Henrike Veith;Noel Southall;Ruili Huang;Tim James

  • Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

    Matthew G. Vander Heiden;Dimitrios Anastasiou;George Poulogiannis;John M. Asara

Frequent Co-Authors

Matthew D. Hall
Matthew D. Hall National Institutes of Health
Qing Lan
Qing Lan National Institutes of Health
Anton Simeonov
Anton Simeonov National Institutes of Health
Nathaniel Rothman
Nathaniel Rothman National Institutes of Health
Roel Vermeulen
Roel Vermeulen Utrecht University
Craig J. Thomas
Craig J. Thomas National Institutes of Health
Martyn T. Smith
Martyn T. Smith University of California, Berkeley
Luoping Zhang
Luoping Zhang University of California, Berkeley
Stephen J. Chanock
Stephen J. Chanock National Institutes of Health

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