Craig J. Thomas

Overview

Best Publications

• Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

  R. Eric Davis;Vu N. Ngo;Georg Lenz;Pavel Tolar

  1945
  Citations

• NMDAR inhibition-independent antidepressant actions of ketamine metabolites

  Panos Zanos;Ruin Moaddel;Patrick J. Morris;Polymnia Georgiou

  1669
  Citations

• Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms

  Panos Zanos;Ruin Moaddel;Patrick J. Morris;Lace M. Riggs

  1242
  Citations

• Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

  Dimitrios Anastasiou;Dimitrios Anastasiou;George Poulogiannis;George Poulogiannis;John M. Asara;John M. Asara;Matthew B. Boxer

  1227
  Citations

• Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

  Eva M. Palsson-McDermott;Anne M. Curtis;Gautam Goel;Gautam Goel;Mario A.R. Lauterbach

  1135
  Citations

• Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.

  Dimitrios Anastasiou;Yimin Yu;William James Israelsen;Jian-Kang Jiang

  785
  Citations

• Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550)

  Kamran Ghoreschi;Michael I. Jesson;Xiong Li;Jamie L. Lee

  715
  Citations

• Exploiting Synthetic Lethality for the Therapy of ABC Diffuse Large B Cell Lymphoma

  Yibin Yang;Arthur L. Shaffer;N.C. Tolga Emre;Michele Ceribelli

  588
  Citations

• Camptothecin: current perspectives.

  Craig J. Thomas;Nicolas J. Rahier;Sidney M. Hecht

  585
  Citations

• Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.

  Rodrigo Romero;Volkan I Sayin;Shawn M Davidson;Matthew R Bauer

  543
  Citations

• Noncanonical TGFβ Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice

  Tammy M. Holm;Jennifer P. Habashi;Jefferson J. Doyle;Djahida Bedja

  519
  Citations

• Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma

  Michail S. Lionakis;Kieron Dunleavy;Mark Roschewski;Brigitte C. Widemann

  509
  Citations

• Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma

  Humsa S. Venkatesh;Lydia T. Tam;Pamelyn J. Woo;James Lennon

  430
  Citations

• High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells

  Lesley A. Mathews Griner;Rajarshi Guha;Paul Shinn;Ryan M. Young

  427
  Citations

• Increased demand for NAD+ relative to ATP drives aerobic glycolysis

  Alba Luengo;Zhaoqi Li;Dan Y. Gui;Lucas B. Sullivan;Lucas B. Sullivan

  350
  Citations

• A multiprotein supercomplex controlling oncogenic signalling in lymphoma

  James D. Phelan;Ryan M. Young;Daniel E. Webster;Sandrine Roulland;Sandrine Roulland

  344
  Citations

• Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin

  Dan Y. Gui;Lucas B. Sullivan;Alba Luengo;Aaron M. Hosios

  324
  Citations

• Cooperative Epigenetic Modulation by Cancer Amplicon Genes

  Lixin Rui;N. C.Tolga Emre;Michael J. Kruhlak;Hye Jung Chung

  312
  Citations

• Identification of oxadiazoles as new drug leads for the control of schistosomiasis

  Ahmed A Sayed;Anton Simeonov;Craig J Thomas;James Inglese

  312
  Citations

• Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

  Matthew G. Vander Heiden;Dimitrios Anastasiou;George Poulogiannis;John M. Asara

  3
  Citations