D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 61 Citations 13,785 168 World Ranking 5057 National Ranking 2449

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

His primary scientific interests are in Cancer research, Biochemistry, Pharmacology, Structure–activity relationship and PKM2. His Cancer research research includes themes of Diffuse large B-cell lymphoma, Signal transduction, breakpoint cluster region, B-cell receptor and Bruton's tyrosine kinase. His work on Small molecule, Enzyme, Thioredoxin and Chinese hamster ovary cell as part of general Biochemistry study is frequently connected to Peroxiredoxin, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.

His Drug study, which is part of a larger body of work in Pharmacology, is frequently linked to Esketamine, bridging the gap between disciplines. His biological study spans a wide range of topics, including Camptothecin, DNA, Beta-Lactamase Inhibitors, DNA Topoisomerase I and High-throughput screening. He has included themes like Cancer cell, Enzyme activator and Pyruvate decarboxylation in his PKM2 study.

His most cited work include:

  • Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma (1127 citations)
  • NMDAR inhibition-independent antidepressant actions of ketamine metabolites (770 citations)
  • Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses (755 citations)

What are the main themes of his work throughout his whole career to date?

Craig J. Thomas focuses on Cancer research, Pharmacology, Biochemistry, Stereochemistry and Kinase. The various areas that he examines in his Cancer research study include Cancer cell, Cancer, Carcinogenesis, Cell growth and PI3K/AKT/mTOR pathway. His work in Pharmacology addresses issues such as Ketamine, which are connected to fields such as Hydroxynorketamine.

His studies in Structure–activity relationship, Pyruvate kinase, Small molecule, PKM2 and Enzyme are all subfields of Biochemistry research. His Pyruvate kinase research is multidisciplinary, relying on both Phosphoenolpyruvate carboxykinase and Cell biology. His study looks at the relationship between Stereochemistry and topics such as Receptor, which overlap with Endocrinology.

He most often published in these fields:

  • Cancer research (30.98%)
  • Pharmacology (16.56%)
  • Biochemistry (15.64%)

What were the highlights of his more recent work (between 2019-2021)?

  • Cancer research (30.98%)
  • Kinase (9.51%)
  • In vivo (7.06%)

In recent papers he was focusing on the following fields of study:

Craig J. Thomas mostly deals with Cancer research, Kinase, In vivo, Pyruvate kinase and Pharmacology. Craig J. Thomas interconnects Cell culture, Protein kinase B, Cell growth, Transcription factor and PI3K/AKT/mTOR pathway in the investigation of issues within Cancer research. His work on LYN as part of his general Kinase study is frequently connected to Cell Migration Assay, thereby bridging the divide between different branches of science.

His studies in In vivo integrate themes in fields like Sickle cell trait, Chronic pain, Renal cell carcinoma, Docetaxel and Hippocampus. His Pyruvate kinase research is multidisciplinary, incorporating elements of PCK2 and Phosphoenolpyruvate carboxykinase. His Pharmacology study combines topics in areas such as Antidepressant, Monoclonal antibody, Mood disorders and Ketamine.

Between 2019 and 2021, his most popular works were:

  • O-GlcNAc regulates gene expression by controlling detained intron splicing. (19 citations)
  • Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway (12 citations)
  • Increased demand for NAD+ relative to ATP drives aerobic glycolysis (10 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Craig J. Thomas spends much of his time researching Cancer research, Cell biology, Pyruvate kinase, Phosphoenolpyruvate carboxykinase and Kinase. The study incorporates disciplines such as Viability assay, Malignant peripheral nerve sheath tumor and Cell growth in addition to Cancer research. His study in Cell biology is interdisciplinary in nature, drawing from both Glycolysis, Metabolism, Oxidative phosphorylation and RNA-Seq.

His work deals with themes such as Allosteric regulation and Proto-oncogene tyrosine-protein kinase Src, which intersect with Glycolysis. His Pyruvate kinase research incorporates elements of Insulin and Pancreatic islets. Craig J. Thomas combines subjects such as Phenotype, Computational biology and Orders of magnitude with his study of Kinase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

R. Eric Davis;Vu N. Ngo;Georg Lenz;Pavel Tolar.
Nature (2010)

1430 Citations

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

Dimitrios Anastasiou;Dimitrios Anastasiou;George Poulogiannis;George Poulogiannis;John M. Asara;John M. Asara;Matthew B. Boxer.
Science (2011)

946 Citations

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

Panos Zanos;Ruin Moaddel;Patrick J. Morris;Polymnia Georgiou.
Nature (2016)

932 Citations

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

Eva M. Palsson-McDermott;Anne M. Curtis;Gautam Goel;Gautam Goel;Mario A.R. Lauterbach.
Cell Metabolism (2015)

596 Citations

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.

Dimitrios Anastasiou;Yimin Yu;William James Israelsen;Jian-Kang Jiang.
Nature Chemical Biology (2012)

559 Citations

Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550)

Kamran Ghoreschi;Michael I. Jesson;Xiong Li;Jamie L. Lee.
Journal of Immunology (2011)

515 Citations

Exploiting Synthetic Lethality for the Therapy of ABC Diffuse Large B Cell Lymphoma

Yibin Yang;Arthur L. Shaffer;N.C. Tolga Emre;Michele Ceribelli.
Cancer Cell (2012)

480 Citations

Camptothecin: current perspectives.

Craig J. Thomas;Nicolas J. Rahier;Sidney M. Hecht.
Bioorganic & Medicinal Chemistry (2004)

451 Citations

Noncanonical TGFβ Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice

Tammy M. Holm;Jennifer P. Habashi;Jefferson J. Doyle;Djahida Bedja.
Science (2011)

439 Citations

High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells

Lesley A. Mathews Griner;Rajarshi Guha;Paul Shinn;Ryan M. Young.
Proceedings of the National Academy of Sciences of the United States of America (2014)

322 Citations

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