World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
112
Citations
52891
World Ranking
495
National Ranking
254

Medicine

D-Index
121
Citations
61090
World Ranking
3575
National Ranking
1969

Research.com Recognitions

  • 2013 - Robert J. and Claire Pasarow Foundation Medical Research Award
  • 2011 - Member of the National Academy of Sciences
  • 2008 - Member of the National Academy of Medicine (NAM)
  • 2005 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Harry C. Dietz is affiliated with Johns Hopkins University School of Medicine in the United States. Their research primarily spans the fields of medicine and biochemistry, genetics, and molecular biology, with notable subfields in genetics, pulmonary and respiratory medicine, cardiology and cardiovascular medicine, surgery, and molecular biology.

The scientist's main research topics include connective tissue disorders research, aortic disease and treatment approaches, cardiac valve diseases and treatments, aortic aneurysm repair treatments, cardiovascular issues in pregnancy, congenital heart disease studies, and genomics and rare diseases.

Dietz has contributed to several publications across multiple venues. Frequent publication venues include Genetics in Medicine, Genetics in Medicine Open, Journal of Thoracic and Cardiovascular Surgery, Journal of Pediatric Orthopaedics, and American Journal of Medical Genetics Part A.

Coauthors frequently collaborating with Dietz comprise Gretchen MacCarrick, Anthony L. Guerrerio, Bart Loeys, Pamela A. Frischmeyer-Guerrerio, and Seema Mital.

Among Dietz's recent papers are the following:

  • A positively selected FBN1 missense variant reduces height in Peruvian individuals (2020, Nature)
  • Loeys-Dietz Syndrome (2021, Advances in experimental medicine and biology)
  • Predictors of Bicuspid Aortic Valve-Associated Aortopathy in Childhood (2020, Circulation Cardiovascular Imaging)
  • Epithelial-intrinsic defects in TGFβR signaling drive local allergic inflammation manifesting as eosinophilic esophagitis (2023, Science Immunology)
  • Cardiovascular Management of Aortopathy in Children: A Scientific Statement From the American Heart Association (2024, Circulation)

Throughout their career, Dietz has received several awards, including the Robert J. and Claire Pasarow Foundation Medical Research Award in 2013, election as a Member of the National Academy of Sciences in 2011, Member of the National Academy of Medicine in 2008, and Fellowship of the American Association for the Advancement of Science in 2005.

Best Publications

  • Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene.

    Harry C. Dietz;Carry R. Cutting;Reed E. Pyeritz;Cheryl L. Maslen

  • The revised Ghent nosology for the Marfan syndrome

    Bart L Loeys;Harry C Dietz;Alan C Braverman;Bert L Callewaert

  • Revised diagnostic criteria for the Marfan syndrome.

    A. De Paepe;R. B. Devereux;H. C. Dietz;R. C. M. Hennekam

  • Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.

    Jennifer P. Habashi;Daniel P. Judge;Tammy M. Holm;Ronald D. Cohn

  • A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2

    Bart L Loeys;Junji Chen;Enid R Neptune;Daniel P Judge

  • Aneurysm Syndromes Caused by Mutations in the TGF-β Receptor

    Bart L. Loeys;Bart L. Loeys;Ulrike Schwarze;Tammy Holm;Bert L. Callewaert

  • Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome

    Enid R. Neptune;Pamela A. Frischmeyer;Dan E. Arking;Loretha Myers

  • Marfan’s syndrome

    Daniel P Judge;Harry C Dietz

  • Nonsense-Mediated mRNA Decay in Health and Disease

    Pamela A. Frischmeyer;Harry C. Dietz

  • Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise.

    Joshua T. Mendell;Neda A. Sharifi;Jennifer L. Meyers;Francisco Martinez-Murillo

  • Angiotensin II Blockade and Aortic-Root Dilation in Marfan's Syndrome

    Benjamin S. Brooke;Jennifer P. Habashi;Daniel P. Judge;Nishant Patel

  • Angiotensin II type 1 receptor blockade attenuates TGF-β–induced failure of muscle regeneration in multiple myopathic states

    Ronald D Cohn;Christel van Erp;Jennifer P Habashi;Arshia A Soleimani

  • Exosome-mediated recognition and degradation of mRNAs lacking a termination codon

    Ambro van Hoof;Pamela A. Frischmeyer;Harry C. Dietz;Roy Parker

  • An mRNA Surveillance Mechanism That Eliminates Transcripts Lacking Termination Codons

    Pamela A. Frischmeyer;Ambro van Hoof;Kathryn O'Donnell;Anthony L. Guerrerio

  • A mutation in the surfactant protein B gene responsible for fatal neonatal respiratory disease in multiple kindreds.

    Lawrence M. Nogee;Gerard Garnier;Harry C. Dietz;Lori Singer

  • Mutations in the human gene for fibrillin-1 (FBN1) in the Marfan syndrome and related disorders

    Harry C. Dietz;Reed E. Pyeritz

  • Multimodality imaging of diseases of the thoracic aorta in adults: From the American society of echocardiography and the european association of cardiovascular imaging: Endorsed by the society of cardiovascular computed tomography and society for cardiovascular magnetic resonance

    Steven A. Goldstein;Arturo Evangelista;Suhny Abbara;Andrew Arai

  • TGF-β–dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome

    Connie M. Ng;Alan Cheng;Loretha A. Myers;Francisco Martinez-Murillo

  • Angiotensin II Type 2 Receptor Signaling Attenuates Aortic Aneurysm in Mice Through ERK Antagonism

    Jennifer P. Habashi;Jefferson J. Doyle;Tammy M. Holm;Hamza Aziz

  • Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1

    Lygia Pereira;Sui Ying Lee;Barbara Gayraud;Kostantinos Andrikopoulos

Frequent Co-Authors

Bart Loeys
Bart Loeys University of Antwerp
Daniel P. Judge
Daniel P. Judge Medical University of South Carolina
Reed E. Pyeritz
Reed E. Pyeritz University of Pennsylvania
Francesco Ramirez
Francesco Ramirez Icahn School of Medicine at Mount Sinai
Lynn Y. Sakai
Lynn Y. Sakai Oregon Health & Science University
Dianna M. Milewicz
Dianna M. Milewicz The University of Texas Health Science Center at Houston
Jennifer E. Van Eyk
Jennifer E. Van Eyk Cedars-Sinai Medical Center
Lut Van Laer
Lut Van Laer University of Antwerp
Paul D. Sponseller
Paul D. Sponseller Johns Hopkins University
David L. Huso
David L. Huso Johns Hopkins University

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