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Medicine

D-Index
87
Citations
37034
World Ranking
13451
National Ranking
165

Overview

Bart Loeys is affiliated with the University of Antwerp in Belgium and has contributed extensively to research in medicine, with a focus on genetics and cardiovascular topics. Their work spans multiple interconnected fields, including medicine and biochemistry, genetics and molecular biology.

Their subfields of expertise encompass genetics, cardiology and cardiovascular medicine, pulmonary and respiratory medicine, molecular biology, and cellular and molecular neuroscience. This interdisciplinary approach supports investigation into complex human diseases at molecular and clinical levels.

Research topics commonly addressed by Bart Loeys include:

  • Connective tissue disorders research
  • Aortic disease and treatment approaches
  • Cardiac electrophysiology and arrhythmias
  • Aortic aneurysm repair treatments
  • Cardiomyopathy and myosin studies
  • Cardiac valve diseases and treatments
  • Genomics and rare diseases

Among recent publications, the following notable papers illustrate the scope and focus of their research:

  • "2023 ESC Guidelines for the management of cardiomyopathies" (2023), published in European Heart Journal
  • "A mutation update for the FLNC gene in myopathies and cardiomyopathies" (2020), published in Human Mutation
  • "Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome" (2020), published in Circulation
  • "Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls" (2020), published in Genetics in Medicine
  • "Extracellular Matrix in Vascular Disease, Part 2/4" (2020), published in Journal of the American College of Cardiology

Bart Loeys frequently publishes in the following journals:

  • Stem Cell Research
  • European Heart Journal
  • Genetics in Medicine
  • Journal of Medical Genetics
  • European Journal of Medical Genetics

Collaboration is a significant aspect of their work, with frequent co-authors including:

  • Aline Verstraeten
  • Josephina Meester
  • Maaike Alaerts
  • Lut Van Laer
  • Johan Saenen

Best Publications

  • The revised Ghent nosology for the Marfan syndrome

    Bart L Loeys;Harry C Dietz;Alan C Braverman;Bert L Callewaert

  • Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.

    Jennifer P. Habashi;Daniel P. Judge;Tammy M. Holm;Ronald D. Cohn

  • A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2

    Bart L Loeys;Junji Chen;Enid R Neptune;Daniel P Judge

  • Aneurysm Syndromes Caused by Mutations in the TGF-β Receptor

    Bart L. Loeys;Bart L. Loeys;Ulrike Schwarze;Tammy Holm;Bert L. Callewaert

  • Angiotensin II Blockade and Aortic-Root Dilation in Marfan's Syndrome

    Benjamin S. Brooke;Jennifer P. Habashi;Daniel P. Judge;Nishant Patel

  • Angiotensin II type 1 receptor blockade attenuates TGF-β–induced failure of muscle regeneration in multiple myopathic states

    Ronald D Cohn;Christel van Erp;Jennifer P Habashi;Arshia A Soleimani

  • Effect of mutation type and location on clinical outcome in 1,013 probands with marfan syndrome or related phenotypes and FBN1 mutations : An international study

    L. Faivre;G. Collod-Beroud;G. Collod-Beroud;B.L. Loeys;A. Child

  • Mutations in Cohesin Complex Members SMC3 and SMC1A Cause a Mild Variant of Cornelia de Lange Syndrome with Predominant Mental Retardation

    Matthew A. Deardorff;Matthew A. Deardorff;Maninder Kaur;Dinah Yaeger;Abhinav Rampuria

  • Atenolol versus Losartan in Children and Young Adults with Marfan's Syndrome

    Ronald V. Lacro;Harry C. Dietz;Lynn A. Sleeper;Anji T. Yetman

  • Noncanonical TGFβ Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice

    Tammy M. Holm;Jennifer P. Habashi;Jefferson J. Doyle;Djahida Bedja

  • Loeys-Dietz syndrome: a primer for diagnosis and management

    Gretchen MacCarrick;James H. Black;Sarah Bowdin;Ismail El-Hamamsy

  • The molecular genetics of Marfan syndrome and related disorders

    Peter N. Robinson;E. Arteaga-Solis;C. Baldock;G. Collod-Béroud

  • Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm

    Mark E. Lindsay;Dorien Schepers;Nikhita Ajit Bolar;Jefferson J. Doyle

  • Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin

    Edgar A. Otto;Bart Loeys;Hemant Khanna;Jan Hellemans

  • Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome

    Paul J Coucke;Andy Willaert;Marja W Wessels;Bert Callewaert

  • Update of the UMD-FBN1 mutation database and creation of an FBN1 polymorphism database.

    Gwenaëlle Collod-Béroud;Saga Le Bourdelles;Lesley Ades;Lesley Ades;Leena Ala-Kokko;Leena Ala-Kokko

  • Homozygosity for a missense mutation in fibulin-5 (FBLN5) results in a severe form of cutis laxa

    Bart Loeys;Lionel Van Maldergem;Geert Mortier;Paul Coucke

  • Circulating transforming growth factor-beta in Marfan syndrome.

    Peter Matt;Florian Schoenhoff;Jennifer Habashi;Tammy Holm

  • Extending the phenotype of recurrent rearrangements of 16p11.2: Deletions in mentally retarded patients without autism and in normal individuals

    E.K. Bijlsma;A.C.J. Gijsbers;J.H.M. Schuurs-Hoeijmakers;A. van Haeringen

  • Ehlers-Danlos syndromes and Marfan syndrome

    Bert Callewaert;Fransiska Malfait;Bart Loeys;Anne De Paepe

Frequent Co-Authors

Lut Van Laer
Lut Van Laer University of Antwerp
Harry C. Dietz
Harry C. Dietz Johns Hopkins University School of Medicine
Anne De Paepe
Anne De Paepe Ghent University Hospital
Paul Coucke
Paul Coucke Ghent University
Geert Mortier
Geert Mortier University of Antwerp
Patrick Segers
Patrick Segers Ghent University
Catherine Boileau
Catherine Boileau Université Paris Cité
Guillaume Jondeau
Guillaume Jondeau Université Paris Cité
Björn Menten
Björn Menten Ghent University Hospital
Laurence Faivre
Laurence Faivre University of Burgundy

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