Wallace Y. Langdon

Overview

Best Publications

• c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

  Gil Levkowitz;Hadassa Waterman;Eli Zamir;Zvi Kam

  1143
  Citations

• Cbl: many adaptations to regulate protein tyrosine kinases

  Christine B. F. Thien;Wallace Y. Langdon

  797
  Citations

• Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors.

  Philippe Soubeyran;Katarzyna Kowanetz;Iwona Szymkiewicz;Wallace Y. Langdon

  713
  Citations

• The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells.

  A W Harris;C A Pinkert;M Crawford;W Y Langdon

  547
  Citations

• The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

  Wallace Y. Langdon;Alan W. Harris;Suzanne Cory;Jerry M. Adams

  540
  Citations

• Mutation of the c-Cbl TKB Domain Binding Site on the Met Receptor Tyrosine Kinase Converts It into a Transforming Protein

  Pascal Peschard;Tanya M Fournier;Louie Lamorte;Monica A Naujokas

  533
  Citations

• Tissue Hyperplasia and Enhanced T-Cell Signalling via ZAP-70 in c-Cbl-Deficient Mice

  Maria A. Murphy;Ralf G. Schnall;Deon J. Venter;Deon J. Venter;Louise Barnett

  480
  Citations

• The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells

  Magdalena Paolino;Axel Choidas;Stephanie Wallner;Blanka Pranjic

  464
  Citations

• v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas.

  W Y Langdon;J W Hartley;S P Klinken;S K Ruscetti

  405
  Citations

• The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the T cell antigen receptor.

  J.A. Donovan;R.L. Wange;Wallace Langdon;L.E. Samelson

  383
  Citations

• The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif.

  Blake Tj;Shapiro M;Morse Hc rd;Langdon Wy

  336
  Citations

• c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses

  Christine B. F. Thien;Wallace Y. Langdon

  312
  Citations

• Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene.

  C.E. Andoniou;C.B.F. Thien;Wallace Langdon

  301
  Citations

• Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling

  Esther Sook Miin Wong;Chee Wai Fong;Jormay Lim;Permeen Yusoff

  282
  Citations

• Association of a chromosome deletion syndrome with a fragile site within the proto-oncogene CBL2

  C. Jones;L. Penny;T. Mattina;S. Yu

  238
  Citations

• Tyrosine Phosphorylation of the c-cbl Proto-oncogene Protein Product and Association with Epidermal Growth Factor (EGF) Receptor upon EGF Stimulation

  Maria L. Galisteo;Ivan Dikic;Andreas G. Batzer;Wallace Y. Langdon

  230
  Citations

• RING Finger Mutations that Abolish c-Cbl-Directed Polyubiquitination and Downregulation of the EGF Receptor Are Insufficient for Cell Transformation

  Christine B.F Thien;Francesca Walker;Wallace Y Langdon

  226
  Citations

• Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells.

  Elena A. Feshchenko;Wallace Y. Langdon;Alexander Y. Tsygankov

  212
  Citations

• A Novel Phosphotyrosine-binding Domain in the N-terminal Transforming Region of Cbl Interacts Directly and Selectively with ZAP-70 in T Cells

  Lupher Ml;Reedquist Ka;Miyake S;Langdon Wy

  211
  Citations

• Stimulation through the T Cell Receptor Induces Cbl Association with Crk Proteins and the Guanine Nucleotide Exchange Protein C3G

  K. A. Reedquist;T. Fukazawa;Govindaswamy Panchamoorthy;W. Y. Langdon

  209
  Citations