D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 80 Citations 36,643 284 World Ranking 1731 National Ranking 44
Medicine D-index 76 Citations 24,666 223 World Ranking 11353 National Ranking 413

Research.com Recognitions

Awards & Achievements

2019 - Fellow of the Australian Academy of Science

2015 - Fellow of the Australian Academy of Health and Medical Science

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Cytokine

Warren S. Alexander mainly investigates Signal transduction, Cell biology, Cancer research, Immunology and Suppressor of cytokine signalling. His Signal transduction research is multidisciplinary, incorporating perspectives in Receptor, Internal medicine, Cytokine and Phosphorylation. Warren S. Alexander combines subjects such as Cellular differentiation and Programmed cell death, Necroptosis with his study of Cell biology.

His research in Cancer research intersects with topics in Cytotoxic T cell, Janus kinase 1, Oncogene and Immunotherapy. His work deals with themes such as Progenitor cell, Stem cell factor, Haematopoiesis and Thrombopoietin, which intersect with Immunology. His Suppressor of cytokine signalling research includes themes of Suppressor of cytokine signaling 1, JAK-STAT signaling pathway, Janus kinase and SOCS2.

His most cited work include:

  • A family of cytokine-inducible inhibitors of signalling (1846 citations)
  • The c- myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice (1508 citations)
  • SOCS3 negatively regulates IL-6 signaling in vivo. (695 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Cell biology, Cancer research, Haematopoiesis, Immunology and Molecular biology. His Cell biology research incorporates elements of Receptor, Programmed cell death and Cellular differentiation. Warren S. Alexander has included themes like Leukemia, Transcription factor, Hematopoietic stem cell and Necroptosis in his Cancer research study.

His research in Haematopoiesis tackles topics such as Progenitor cell which are related to areas like Bone marrow. The Signal transduction study combines topics in areas such as Phosphorylation and Leukemia inhibitory factor. His studies deal with areas such as Suppressor of cytokine signaling 1, T cell, Endocrinology and SOCS3 as well as Cytokine.

He most often published in these fields:

  • Cell biology (46.22%)
  • Cancer research (42.16%)
  • Haematopoiesis (40.27%)

What were the highlights of his more recent work (between 2014-2021)?

  • Cell biology (46.22%)
  • Haematopoiesis (40.27%)
  • Cancer research (42.16%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Cell biology, Haematopoiesis, Cancer research, Progenitor cell and Stem cell. His study in Cell biology is interdisciplinary in nature, drawing from both Embryonic stem cell, Immunoglobulin gene, Cellular differentiation, Downregulation and upregulation and Regulator. His studies in Haematopoiesis integrate themes in fields like Myeloid, Cytotoxic T cell and Regulation of gene expression.

His Cancer research research integrates issues from Inflammation, Apoptosis, Programmed cell death, Necroptosis and Leukemia. The Progenitor cell study combines topics in areas such as Thrombopoietin receptor, Gene expression, Blood cell, Molecular biology and Bone marrow. The concepts of his Thrombopoietin study are interwoven with issues in Megakaryopoiesis and Cytokine.

Between 2014 and 2021, his most popular works were:

  • Robust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression (346 citations)
  • RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL (309 citations)
  • CIS is a potent checkpoint in NK cell–mediated tumor immunity (138 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Cytokine

His primary areas of investigation include Cancer research, Haematopoiesis, Progenitor cell, Stem cell and Cell biology. His work carried out in the field of Cancer research brings together such families of science as CISH, Apoptosis, Janus kinase 1, Interferon gamma and Leukemia. His work focuses on many connections between Haematopoiesis and other disciplines, such as Regulation of gene expression, that overlap with his field of interest in Homeobox, Epigenetic Repression and Myelopoiesis.

In his study, which falls under the umbrella issue of Progenitor cell, Database is strongly linked to Transcriptome. His study looks at the intersection of Stem cell and topics like Embryonic stem cell with Transplantation. His Cell biology research is multidisciplinary, relying on both Endothelial stem cell, Cellular differentiation, Molecular biology and Programmed cell death, Necroptosis.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A family of cytokine-inducible inhibitors of signalling

Robyn Starr;Tracy A. Willson;Elizabeth M. Viney;Leecia J. L. Murray.
Nature (1997)

2529 Citations

The c- myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

J. M. Adams;A. W. Harris;C. A. Pinkert;L. M. Corcoran.
Nature (1985)

1998 Citations

The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response.

Warren S. Alexander;Douglas J. Hilton.
Annual Review of Immunology (2004)

1007 Citations

Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells.

Timothy Gainsford;Tracy A. Willson;Donald Metcalf;Emanuela Handman.
Proceedings of the National Academy of Sciences of the United States of America (1996)

934 Citations

SOCS3 negatively regulates IL-6 signaling in vivo.

Ben A Croker;Danielle L Krebs;Jian-Guo Zhang;Sam Wormald.
Nature Immunology (2003)

883 Citations

SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine

Warren S Alexander;Robyn Starr;Robyn Starr;Jennifer E Fenner;Clare L Scott;Clare L Scott.
Cell (1999)

874 Citations

Twenty proteins containing a C-terminal SOCS box form five structural classes

Douglas J. Hilton;Rachael T. Richardson;Warren S. Alexander;Elizabeth M. Viney.
Proceedings of the National Academy of Sciences of the United States of America (1998)

851 Citations

Suppressors of cytokine signalling (SOCS) in the immune system.

Warren S. Alexander.
Nature Reviews Immunology (2002)

821 Citations

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy;Peter E. Czabotar;Peter E. Czabotar;Joanne M. Hildebrand;Joanne M. Hildebrand;Isabelle S. Lucet.
Immunity (2013)

780 Citations

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

Jian Guo Zhang;Alison Farley;Sandra E. Nicholson;Tracy A. Willson.
Proceedings of the National Academy of Sciences of the United States of America (1999)

755 Citations

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