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Biology and Biochemistry

D-Index
51
Citations
18434
World Ranking
16932
National Ranking
475

Overview

Tracy A. Willson is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research spans multiple disciplines including biochemistry, genetics, molecular biology, medicine, and immunology and microbiology.

Their work covers various subfields such as molecular biology, immunology, genetics, neurology, and cardiology and cardiovascular medicine. Main research topics addressed include T-cell and B-cell immunology, immunotherapy and immune responses, genomics and chromatin dynamics, interferon and immune responses, viral infections and immunology research, cell death mechanisms and regulation, and immune cell function and interaction.

Recent publications by Willson include:

  • "A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction," 2020, Nature Communications
  • "An Erg-driven transcriptional program controls B cell lymphopoiesis," 2020, Nature Communications
  • "Clonal multi-omics reveals Bcor as a negative regulator of emergency dendritic cell development," 2021, Immunity
  • "Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid-binding residues," 2020, Science Signaling
  • "BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation," 2022, Nature Communications

Willson's frequent co-authors include Matthew E. Ritchie, Marnie E. Blewitt, Samuel N. Young, Adrienne A. Hilton, and Melanie Bahlo. Their collaborative work has resulted in multiple publications together.

The primary venues distributing Willson's research findings are:

  • Nature Communications
  • Immunity
  • Science Signaling
  • Brain Communications
  • Biochemical Journal

Best Publications

  • A family of cytokine-inducible inhibitors of signalling

    Robyn Starr;Tracy A. Willson;Elizabeth M. Viney;Leecia J. L. Murray

  • Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

    R L Williams;D J Hilton;S Pease;T A Willson

  • SOCS3 negatively regulates IL-6 signaling in vivo.

    Ben A Croker;Danielle L Krebs;Jian-Guo Zhang;Sam Wormald

  • Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells.

    Timothy Gainsford;Tracy A. Willson;Donald Metcalf;Emanuela Handman

  • Twenty proteins containing a C-terminal SOCS box form five structural classes

    Douglas J. Hilton;Rachael T. Richardson;Warren S. Alexander;Elizabeth M. Viney

  • The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

    Jian Guo Zhang;Alison Farley;Sandra E. Nicholson;Tracy A. Willson

  • Gigantism in mice lacking suppressor of cytokine signalling-2

    Donald Metcalf;Christopher J. Greenhalgh;Elizabeth Viney;Tracy A. Willson

  • Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

    Sandra E. Nicholson;David De Souza;Louis J. Fabri;Jason Corbin

  • Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

    Sandra E. Nicholson;Tracy A. Willson;Alison Farley;Robyn Starr

  • Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

    Douglas J. Hilton;Jian-Guo Zhang;Donald Metcalf;Warren S. Alexander

  • Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1

    Robyn Starr;Donald Metcalf;Andrew G. Elefanty;Marta Brysha

  • Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction.

    D J Hilton;A A Hilton;A Raicevic;S Rakar

  • ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity

    Matthew D. Young;Tracy A. Willson;Matthew J. Wakefield;Evelyn Trounson

  • Molecular cloning and expression of the human homologue of the murine gene encoding myeloid leukemia-inhibitory factor

    Nicholas M. Gough;David P. Gearing;Julie A. King;Tracy A. Willson

  • The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells.

    Stephen J Loughran;Elizabeth A Kruse;Elizabeth A Kruse;Douglas F Hacking;Douglas F Hacking;Carolyn A de Graaf;Carolyn A de Graaf

  • SOCS2 negatively regulates growth hormone action in vitro and in vivo

    Christopher J. Greenhalgh;Elizabeth Rico-Bautista;Mattias Lorentzon;Anne L. Thaus

  • Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned Il-13 receptor and Il-4 receptor alpha-chains.

    Jian-Guo Zhang;Douglas J. Hilton;Tracy A. Willson;Clare McFarlane

  • Suppressor screen in Mpl-/- mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling

    Marina R. Carpinelli;Douglas J. Hilton;Donald Metcalf;Jennifer L. Antonchuk

  • Biological Evidence That SOCS-2 Can Act Either as an Enhancer or Suppressor of Growth Hormone Signaling

    Christopher J. Greenhalgh;Donald Metcalf;Anne L. Thaus;Jason E. Corbin

  • LEUKEMIA INHIBITORY FACTOR - A NOVEL BONE-ACTIVE CYTOKINE

    I. R. Reid;C. Lowe;J. Cornish;S. J. M. Skinner

Frequent Co-Authors

Douglas J. Hilton
Douglas J. Hilton Walter and Eliza Hall Institute of Medical Research
Nicos A. Nicola
Nicos A. Nicola Walter and Eliza Hall Institute of Medical Research
Warren S. Alexander
Warren S. Alexander Walter and Eliza Hall Institute of Medical Research
Donald Metcalf
Donald Metcalf Walter and Eliza Hall Institute of Medical Research
Jian-Guo Zhang
Jian-Guo Zhang Beijing Institute for Brain Disorders
Sandra E. Nicholson
Sandra E. Nicholson Walter and Eliza Hall Institute of Medical Research
Benjamin T. Kile
Benjamin T. Kile University of Adelaide
Nicholas M. Gough
Nicholas M. Gough Nick Gough & Associates Pty Ltd
Marnie E. Blewitt
Marnie E. Blewitt Walter and Eliza Hall Institute of Medical Research
Seth L. Masters
Seth L. Masters Hudson Institute of Medical Research

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