2026 Sandra E. Nicholson: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	49	17898	16425	513	493	141	11722

Overview

Sandra E. Nicholson is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research spans multiple disciplines including immunology, microbiology, medicine, biochemistry, genetics, and molecular biology.

The primary fields of study for their work include:

Immunology and Microbiology
Medicine
Biochemistry, Genetics and Molecular Biology

Their subfields of study emphasize:

Immunology
Molecular Biology
Oncology
Pharmacology
Ophthalmology

Core topics addressed in their research cover areas such as:

Cytokine Signaling Pathways and Interactions
Immune Cell Function and Interaction
Interferon and Immune Responses
T-cell and B-cell Immunology
Medicinal Plant Pharmacodynamics Research
Immunotherapy and Immune Responses
Cancer Immunotherapy and Biomarkers

Sandra E. Nicholson has published extensively in various scientific journals. Some notable papers include:

CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8+ T Cells, 2020, Immunity
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway, 2022, Immunity
Natural Killer Cells: Tumor Surveillance and Signaling, 2020, Cancers
SOCS1 is a critical checkpoint in immune homeostasis, inflammation and tumor immunity, 2024, Frontiers in Immunology
Large-scale survey and database of high affinity ligands for peptide recognition modules, 2020, Molecular Systems Biology

Frequent coauthors in their research work include:

Jeffrey J. Babon
Lizeth G. Meza Guzman
Narelle Keating
Grace M. Bidgood
Karen Doggett

The common venues for their publications reflect areas of immunology and molecular biology, including:

bioRxiv (Cold Spring Harbor Laboratory)
Immunity
Frontiers in Immunology
Nature Communications
Immunology and Cell Biology

Best Publications

Twenty proteins containing a C-terminal SOCS box form five structural classes

Douglas J. Hilton;Rachael T. Richardson;Warren S. Alexander;Elizabeth M. Viney

925
Citations
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

Jian Guo Zhang;Alison Farley;Sandra E. Nicholson;Tracy A. Willson

831
Citations
SOCS regulation of the JAK/STAT signalling pathway

Ben A. Croker;Hiu Kiu;Sandra E. Nicholson

769
Citations
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

Ashley Scott Mansell;Rosealee Anne Smith;Sarah L Doyle;Pearl Gray

673
Citations
Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

Sandra E. Nicholson;David De Souza;Louis J. Fabri;Jason Corbin

584
Citations
Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

Sandra E. Nicholson;Tracy A. Willson;Alison Farley;Robyn Starr

543
Citations
Biology and significance of the JAK/STAT signalling pathways.

Hiu Kiu;Sandra E Nicholson

492
Citations
CIS is a potent checkpoint in NK cell–mediated tumor immunity

Rebecca B. Delconte;Tatiana B Kolesnik;Laura F. Dagley;Laura F. Dagley;Jai Rautela;Jai Rautela

394
Citations
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation

Seth L. Masters;Seth L. Masters;Vasiliki Lagou;Isabelle Jéru;Isabelle Jéru;Paul J. Baker;Paul J. Baker

309
Citations
Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation.

Sandra E. Nicholson;Andrew C. Oates;Ailsa G. Harpur;Andrew Ziemiecki

263
Citations
Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2.

Rebecca A.R. Piganis;Nicole A. De Weerd;Jodee A. Gould;Christian W. Schindler

246
Citations
Suppression of cytokine signaling: The SOCS perspective

Edmond M. Linossi;Jeffrey J. Babon;Jeffrey J. Babon;Douglas J. Hilton;Douglas J. Hilton;Sandra E. Nicholson;Sandra E. Nicholson

222
Citations
The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo.

Jian-Guo Zhang;Donald Metcalf;Steven Rakar;Maria Asimakis

201
Citations
Distinct Regions of the Granulocyte Colony-Stimulating Factor Receptor Are Required for Tyrosine Phosphorylation of the Signaling Molecules JAK2, Stat3, and p42, p44MAPK

SE Nicholson;U Novak;SF Ziegler;JE Layton

195
Citations
The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability

Jeffrey J. Babon;Edward J. McManus;Shenggen Yao;David P. DeSouza

187
Citations
SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.

Danielle L. Krebs;Rachel T. Uren;Donald Metcalf;Steven Rakar

183
Citations
Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells

Priyanka Sathe;Rebecca B. Delconte;Fernando Souza-Fonseca-Guimaraes;Cyril Seillet

183
Citations
The SOCS proteins: a new family of negative regulators of signal transduction.

Sandra E. Nicholson;Douglas J. Hilton

182
Citations
Suppressors of cytokine signaling (SOCS): Negative regulators of signal transduction

Warren S. Alexander;Robyn Starr;Donald Metcalf;Sandra E. Nicholson

169
Citations
Familial Autoinflammation with Neutrophilic Dermatosis Reveals a Novel Regulatory Mechanism of Pyrin Activation

P. J. Baker;V. Lagou;I. Jeru;L. Van Eyck

1
Citations