His primary areas of study are Immunology, Cell biology, Signal transduction, Cytokine and Interferon. His Immunology study frequently draws connections between adjacent fields such as Cancer therapy. His studies in Cell biology integrate themes in fields like Genetics, Cellular differentiation, Gene and Immune system.
His research integrates issues of Suppressor of cytokine signaling 1, Receptor, Toll-like receptor and Transactivation in his study of Signal transduction. Paul J. Hertzog has included themes like stat and Effector in his Cytokine study. His Interferon research is multidisciplinary, relying on both Cell culture and Innate immune system.
Paul J. Hertzog mainly focuses on Immunology, Cell biology, Interferon, Molecular biology and Signal transduction. His Immunology study frequently links to other fields, such as Virology. In his study, Gene expression and Regulation of gene expression is inextricably linked to Transcription factor, which falls within the broad field of Cell biology.
The study incorporates disciplines such as Cancer research and Gene in addition to Interferon. His study focuses on the intersection of Molecular biology and fields such as Monoclonal antibody with connections in the field of Polyclonal antibodies. Much of his study explores Signal transduction relationship to Receptor.
His scientific interests lie mostly in Immunology, Interferon, Cell biology, Immune system and Signal transduction. His Immunology study integrates concerns from other disciplines, such as Disease and Virology. His Interferon research incorporates elements of Function, Virus, Gene, Bone metastasis and Innate immune system.
His work carried out in the field of Cell biology brings together such families of science as Chromatin, Hormone, Transcription factor and T cell differentiation. His Immune system research is multidisciplinary, incorporating elements of Cancer research and Cellular differentiation. His Signal transduction research is multidisciplinary, incorporating perspectives in Receptor and Interferon gamma.
His main research concerns Immunology, Immune system, Interferon, Cell biology and Transcription factor. His Immunology study combines topics in areas such as RNA, Cell, Disease and Virology. Paul J. Hertzog has researched Disease in several fields, including Direct effects, Cancer immunotherapy, Potential toxicity, Cancer therapy and Cancer Microenvironment.
His studies deal with areas such as IRF7, Cytokine, Small hairpin RNA, Virus and Interferon-stimulated gene as well as Interferon. His Cell biology research is mostly focused on the topic Cell signaling. As a member of one scientific family, Paul J. Hertzog mostly works in the field of Transcription factor, focusing on Gene expression and, on occasion, Regulation of gene expression.
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Interferon-γ: an overview of signals, mechanisms and functions
Kate Schroder;Paul John Hertzog;Timothy Ravasi;David A Hume.
Journal of Leukocyte Biology (2004)
SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine
Warren S Alexander;Robyn Starr;Robyn Starr;Jennifer E Fenner;Clare L Scott;Clare L Scott.
Cell (1999)
Type I IFNs Enhance the Terminal Differentiation of Dendritic Cells
Thomas Luft;Ken C Pang;Elisabeth Thomas;Paul J Hertzog.
Journal of Immunology (1998)
Mice with a Homozygous Null Mutation for the Most Abundant Glutathione Peroxidase, Gpx1, Show Increased Susceptibility to the Oxidative Stress-inducing Agents Paraquat and Hydrogen Peroxide
Judy Bettina De Haan;Cecile Bladier;Peter Griffiths;Michael J Kelner.
Journal of Biological Chemistry (1998)
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
Ashley Scott Mansell;Rosealee Anne Smith;Sarah L Doyle;Pearl Gray.
Nature Immunology (2006)
Differential Production of IL-12, IFN-α, and IFN-γ by Mouse Dendritic Cell Subsets
Hubertus Hochrein;Hubertus Hochrein;Ken Shortman;David Vremec;Bernadette M Scott.
Journal of Immunology (2001)
INTERFEROME v2.0: an updated database of annotated interferon-regulated genes
Irina Rusinova;Samuel Forster;Simon Xiaoming Yu;Anitha Kannan.
Nucleic Acids Research (2012)
Cathepsin K knockout mice develop osteopetrosis due to a deficit in matrix degradation but not demineralization.
Maxine Gowen;Francesca Lazner;Robert Dodds;Rasesh Kapadia.
Journal of Bone and Mineral Research (1999)
Antitumour actions of interferons: implications for cancer therapy
Belinda S. Parker;Jai Rautela;Jai Rautela;Jai Rautela;Paul J. Hertzog;Paul J. Hertzog.
Nature Reviews Cancer (2016)
A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses
Seung Y. Hwang;Paul J. Hertzog;Kerry A. Holland;Sony H. Sumarsono.
Proceedings of the National Academy of Sciences of the United States of America (1995)
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