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Luke A. J. O'Neill

Luke A. J. O'Neill

Trinity College Dublin
Ireland

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Immunology
Ireland
2026
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Biology and Biochemistry
Ireland
2023

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Immunology 159 84 81 1 1 519 113183

Luke A. J. O'Neill publications per year

The chart shows the history of publications by Luke A. J. O'Neill between 1988 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Luke A. J. O'Neill published across 38 years, from 1988 to 2025, averaging 17.1 papers a year. Output peaked at 37 publications in 2001. 38 of the 649 publications appeared in the last two years.

No. of publications
10 20 30
Bar chart. Horizontal axis: year, 1988 to 2025. Vertical axis: number of publications, 0 to 37. Peak 37 publications in 2001. 1988: 3 publications 1989: 1 publication 1990: 3 publications 1991: 0 publications 1992: 5 publications 1993: 4 publications 1994: 3 publications 1995: 14 publications 1996: 10 publications 1997: 10 publications 1998: 5 publications 1999: 7 publications 2000: 20 publications 2001: 37 publications 2002: 13 publications 2003: 17 publications 2004: 15 publications 2005: 14 publications 2006: 13 publications 2007: 21 publications 2008: 25 publications 2009: 25 publications 2010: 26 publications 2011: 24 publications 2012: 17 publications 2013: 32 publications 2014: 27 publications 2015: 24 publications 2016: 31 publications 2017: 31 publications 2018: 22 publications 2019: 21 publications 2020: 22 publications 2021: 26 publications 2022: 18 publications 2023: 25 publications 2024: 18 publications 2025: 20 publications
1988 2025

649 publications in total across all disciplines

View publications per year as a table
Luke A. J. O'Neill: publications per year, 1988 to 2025
Year Publications
1988 3
1989 1
1990 3
1991 0
1992 5
1993 4
1994 3
1995 14
1996 10
1997 10
1998 5
1999 7
2000 20
2001 37
2002 13
2003 17
2004 15
2005 14
2006 13
2007 21
2008 25
2009 25
2010 26
2011 24
2012 17
2013 32
2014 27
2015 24
2016 31
2017 31
2018 22
2019 21
2020 22
2021 26
2022 18
2023 25
2024 18
2025 20
Total 649
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Luke A. J. O'Neill publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Luke A. J. O'Neill sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 76 bars. Horizontal axis: publications, 62–71 to 807+. Vertical axis: number of scientists, 0 to 189. Most scientists, 189, have 152–161 publications. The last bar groups every scientist with 807 publications or more. The highlighted bar, 512–521 publications, is where this scientist sits. 62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientist 807+ publications: 100 scientists
62–71 publications 807+

This scientist: 519 publications — 91st percentile

91% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

View publications distribution as a table
Number of Immunology scientists by publication count, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
Publications Scientists This scientist
62–71 9
72–81 23
82–91 40
92–101 72
102–111 86
112–121 108
122–131 150
132–141 160
142–151 159
152–161 189
162–171 166
172–181 181
182–191 188
192–201 187
202–211 178
212–221 158
222–231 168
232–241 159
242–251 160
252–261 148
262–271 116
272–281 125
282–291 115
292–301 111
302–311 95
312–321 97
322–331 97
332–341 99
342–351 96
352–361 69
362–371 76
372–381 71
382–391 71
392–401 62
402–411 54
412–421 41
422–431 63
432–441 53
442–451 31
452–461 42
462–471 40
472–481 29
482–491 34
492–501 30
502–511 23
512–521 41 519
522–531 29
532–541 28
542–551 16
552–561 18
562–571 18
572–581 17
582–591 17
592–601 17
602–611 19
612–621 13
622–631 12
632–641 11
642–651 16
652–661 9
662–671 5
672–681 13
682–691 12
692–701 6
702–711 6
712–721 9
722–731 9
732–741 6
742–751 11
752–761 10
762–771 7
772–781 12
782–791 7
792–801 5
802–806 1
807+ 100
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Luke A. J. O'Neill D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Luke A. J. O'Neill sits on this spectrum.

No. of scientists
50 100 150 200
Bar chart with 60 bars. Horizontal axis: D-Index, 40–41 to 157+. Vertical axis: number of scientists, 0 to 201. Most scientists, 201, have 58–59 D-Index. The last bar groups every scientist with 157 D-Index or more. The highlighted bar, 157+ D-Index, is where this scientist sits. 40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40–41 D-Index 157+

This scientist: 159 D-Index — 98th percentile

98% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

View D-Index distribution as a table
Number of Immunology scientists by D-index, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
D-Index Scientists This scientist
40–41 28
42–43 91
44–45 157
46–47 192
48–49 175
50–51 188
52–53 177
54–55 155
56–57 194
58–59 201
60–61 197
62–63 201
64–65 173
66–67 167
68–69 172
70–71 199
72–73 184
74–75 133
76–77 163
78–79 127
80–81 121
82–83 125
84–85 121
86–87 102
88–89 96
90–91 75
92–93 72
94–95 74
96–97 66
98–99 68
100–101 49
102–103 60
104–105 54
106–107 36
108–109 23
110–111 52
112–113 41
114–115 34
116–117 25
118–119 28
120–121 11
122–123 20
124–125 27
126–127 19
128–129 20
130–131 16
132–133 17
134–135 14
136–137 15
138–139 9
140–141 11
142–143 9
144–145 9
146–147 7
148–149 7
150–151 7
152–153 5
154–155 8
156 6
157+ 96 159
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Research.com Recognitions

  • 2026 - Research.com Immunology in Ireland Leader Award
  • 2025 - Research.com Immunology in Ireland Leader Award
  • 2023 - Research.com Biology and Biochemistry in Ireland Leader Award
  • 2022 - Research.com Biology and Biochemistry in Ireland Leader Award
  • 2016 - Fellow of the Royal Society, United Kingdom
  • 2012 - Gold Medal, Royal Irish Academy Life Sciences
  • 2004 - Member of the Royal Irish Academy
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Luke A. J. O'Neill is affiliated with Trinity College Dublin in Ireland. Their research focuses broadly on immunology, microbiology, biochemistry, genetics, molecular biology, and medicine. Their work encompasses several subfields including immunology, molecular biology, epidemiology, infectious diseases, and genetics.

The scientist's research primarily addresses topics such as immune cells in cancer, inflammasome and immune disorders, interferon and immune responses, immune cell function and interaction, immune response and inflammation, immune responses and vaccinations, and IL-33, ST2, and ILC pathways.

Frequent co-authors collaborating with Luke A. J. O'Neill include Alexander Hooftman, Dylan G. Ryan, Tristram A.J. Ryan, Emily A. Day, and Anne F. McGettrick.

Their publications often appear in leading scientific journals. Frequent publication venues include:

  • Nature Immunology
  • Cell Metabolism
  • Nature Communications
  • Nature
  • Cells

Significant recent papers include:

  • The Role of HIF in Immunity and Inflammation, 2020, Cell Metabolism
  • The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation, 2020, Cell Metabolism
  • BCG-induced trained immunity: can it offer protection against COVID-19?, 2020, Nature Reviews Immunology
  • Trained immunity, tolerance, priming and differentiation: distinct immunological processes, 2020, Nature Immunology
  • Targeting immunometabolism as an anti-inflammatory strategy, 2020, Cell Research

Luke A. J. O'Neill's research has received recognition in the form of several awards. These include being a Fellow of the Royal Society, United Kingdom, since 2016; receiving the Gold Medal from the Royal Irish Academy in Life Sciences in 2012; membership in the Royal Irish Academy since 2004; and election to the European Molecular Biology Organization (EMBO).

Best Publications

  • Succinate is an inflammatory signal that induces IL-1β through HIF-1α

    G. M. Tannahill;A. M. Curtis;J. Adamik;E. M. Palsson-McDermott

  • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

    Luke A. J. O'Neill;Andrew G. Bowie

  • A guide to immunometabolism for immunologists

    Luke A. J. O'Neill;Rigel J. Kishton;Jeff Rathmell

  • A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

    Rebecca C Coll;Avril A B Robertson;Jae Jin Chae;Sarah C Higgins

  • Trained immunity: A program of innate immune memory in health and disease

    Mihai G. Netea;Leo A. B. Joosten;Eicke Latz;Kingston H. G. Mills

  • mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity

    Shih-Chin Cheng;Jessica Quintin;Robert A. Cramer;Kelly M. Shepardson

  • The History of Toll-like Receptors - Redefining Innate Immunity

    Luke A. J. O'Neill;Douglas Golenbock;Andrew G. Bowie

  • Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

    Evanna L. Mills;Beth Kelly;Angela Logan;Ana S.H. Costa

  • Human polymorphism at microRNAs and microRNA target sites.

    Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang

  • Negative regulation of Toll-like receptor-mediated immune responses

    Foo Y. Liew;Damo Xu;Elizabeth K. Brint;Luke A. J. O'Neill

  • Metabolic reprogramming in macrophages and dendritic cells in innate immunity

    Beth Kelly;Luke A J O'Neill

  • Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

    Evanna L Mills;Dylan G Ryan;Hiran A Prag;Dina Dikovskaya

  • Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

    Katherine A. Fitzgerald;Eva M. Palsson-McDermott;Andrew G. Bowie;Andrew G. Bowie;Caroline A. Jefferies

  • Immunometabolism governs dendritic cell and macrophage function

    Luke A.J. O’Neill;Edward J. Pearce

  • Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4

    Eva M Pålsson-McDermott;Luke A J O'Neill

  • Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

    Seth L Masters;Aisling Dunne;Shoba L Subramanian;Rebecca L Hull

  • Resolution of inflammation: state of the art, definitions and terms.

    Charles N. Serhan;Sue D. Brain;Christopher D. Buckley;Derek W. Gilroy

  • NF-kB: a crucial transcription factor for glial and neuronal cell function

    L. ONeill;Christian Kaltschmidt

  • Metabolism of inflammation limited by AMPK and pseudo-starvation

    Luke A. J. O'Neill;D. Grahame Hardie

  • Mitochondria are the powerhouses of immunity.

    Evanna L Mills;Beth Kelly;Luke A J O'Neill

  • Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

    Frederick J Sheedy;Eva Palsson-McDermott;Elizabeth J Hennessy;Cara Martin

  • Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries.

    Andrew Bowie;Luke A.J O’Neill

Frequent Co-Authors

Mark E. Cooper
Mark E. Cooper Monash University
Andrew G. Bowie
Andrew G. Bowie Trinity College Dublin
Katherine A. Fitzgerald
Katherine A. Fitzgerald University of Massachusetts Chan Medical School
Mihai G. Netea
Mihai G. Netea Radboud University
Kingston H. G. Mills
Kingston H. G. Mills Trinity College Dublin
Ramnik J. Xavier
Ramnik J. Xavier Broad Institute
Seth L. Masters
Seth L. Masters Hudson Institute of Medical Research
Hugh J. Byrne
Hugh J. Byrne Technological University Dublin
Kate Schroder
Kate Schroder University of Queensland
Eicke Latz
Eicke Latz German Rheumatism Research Centre

External Links

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Best Scientists Citing Luke A. J. O'Neill

Mihai G. Netea

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Publications: 352

Shizuo Akira

Shizuo Akira

Osaka University

Publications: 204

Leo A. B. Joosten

Leo A. B. Joosten

Radboud University

Publications: 166

Eicke Latz

Eicke Latz

German Rheumatism Research Centre

Publications: 151

Xuetao Cao

Xuetao Cao

Chinese Academy of Medical Sciences & Peking Union Medical College

Publications: 147

Charles A. Dinarello

Charles A. Dinarello

University of Colorado Anschutz Medical Campus

Publications: 99

Katherine A. Fitzgerald

Katherine A. Fitzgerald

University of Massachusetts Chan Medical School

Publications: 98

Alberto Mantovani

Alberto Mantovani

Humanitas University

Publications: 95

Salvatore Cuzzocrea

Salvatore Cuzzocrea

University of Messina

Publications: 78

Charles N. Serhan

Charles N. Serhan

Brigham and Women's Hospital

Publications: 76

Douglas T. Golenbock

Douglas T. Golenbock

University of Massachusetts Chan Medical School

Publications: 75

Philip M. Hansbro

Philip M. Hansbro

University of Technology Sydney

Publications: 74

Stefanie N. Vogel

Stefanie N. Vogel

University of Maryland, Baltimore

Publications: 65

Richard A. Flavell

Richard A. Flavell

Yale University

Publications: 63

Andrew G. Bowie

Andrew G. Bowie

Trinity College Dublin

Publications: 60

Ashley Mansell

Ashley Mansell

Hudson Institute of Medical Research

Publications: 56

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