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Microbiology

D-Index
57
Citations
11949
World Ranking
3572
National Ranking
114

Overview

Ashley Mansell is affiliated with the Hudson Institute of Medical Research in Australia. Their research primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these areas, their work emphasizes Immunology, Molecular Biology, Pulmonary and Respiratory Medicine, Surgery, and Epidemiology as key subfields.

Their research focuses on several main topics, notably inflammasome and immune disorders, IL-33, ST2, and ILC pathways, immune response and inflammation, heme oxygenase-1 and carbon monoxide, reproductive system and pregnancy, immune cells in cancer, and interferon and immune responses.

Recent publications by Mansell include the following papers:

  • Evaluation of inflammation and follicle depletion during ovarian ageing in mice (2021) published in Scientific Reports
  • STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression (2020) published in Nature Communications
  • The Inflammasome Contributes to Depletion of the Ovarian Reserve During Aging in Mice (2021) published in Frontiers in Cell and Developmental Biology
  • IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone/Salt-Induced Hypertension in Mice (2021) published in Hypertension
  • Interleukin-1β exacerbates disease and is a potential therapeutic target to reduce pulmonary inflammation during severe influenza A virus infection (2021) published in Immunology and Cell Biology

Mansell frequently publishes in several scientific venues, including:

  • Nature Communications
  • Immunology and Cell Biology
  • Cell Death and Disease
  • Scientific Reports
  • Frontiers in Cell and Developmental Biology

The scientist collaborates regularly with a group of frequent co-authors, including Michelle D. Tate, Christopher M. Harpur, Maggie Lam, Sarah Rosli, and Kristian Barry. These collaborations have contributed to a diverse range of research output in the biomedical sciences.

Best Publications

  • Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

    Katherine A. Fitzgerald;Eva M. Palsson-McDermott;Andrew G. Bowie;Andrew G. Bowie;Caroline A. Jefferies

  • Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

    Ashley Scott Mansell;Rosealee Anne Smith;Sarah L Doyle;Pearl Gray

  • Central administration of leptin to ovariectomized ewes inhibits food intake without affecting the secretion of hormones from the pituitary gland: evidence for a dissociation of effects on appetite and neuroendocrine function.

    Belinda A. Henry;James W. Goding;Warren S. Alexander;Alan J. Tilbrook

  • IL-6 Trans-Signaling Modulates TLR4-Dependent Inflammatory Responses via STAT3

    Claire J Greenhill;Stefan Rose-John;Rami Lissilaa;Walter Ferlin

  • Toll-like receptors: the swiss army knife of immunity and vaccine development

    Jennifer K Dowling;Jennifer K Dowling;Ashley Mansell;Ashley Mansell

  • Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia

    Kristian Lee Jones;Ashley Scott Mansell;Shane Patella;Bernadette Maree Scott

  • A type III effector antagonizes death receptor signalling during bacterial gut infection

    Jaclyn S Pearson;Cristina Giogha;Sze Ying Ong;Catherine Lydia Kennedy

  • Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease.

    Julie McAuley;Michelle Tate;Charley Mackenzie-kludas;Anita Pinar

  • MyD88 Adapter-like (Mal)/TIRAP Interaction with TRAF6 Is Critical for TLR2- and TLR4-mediated NF-κB Proinflammatory Responses

    Brett Verstak;Kamalpreet Nagpal;Stephen Paul Bottomley;Douglas T Golenbock

  • Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension

    Shalini M Krishnan;Yeong H Ling;Brooke M Huuskes;Dorota M Ferens

  • IL-1β and IL-18: inflammatory markers or mediators of hypertension?

    Shalini Murali Krishnan;Christopher Graeme Sobey;Eicke Latz;Eicke Latz;Eicke Latz;Ashley Scott Mansell

  • Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses

    Ana Maria Bulau;Marcel F. Nold;Suzhao Li;Claudia A. Nold-Petry

  • Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2.

    Rebecca A.R. Piganis;Nicole A. De Weerd;Jodee A. Gould;Christian W. Schindler

  • TRIF‐dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target

    M. Obayed Ullah;Matthew J. Sweet;Ashley Mansell;Stuart Kellie

  • The hepatitis B e antigen (HBeAg) targets and suppresses activation of the toll-like receptor signaling pathway.

    Tali Lang;Camden Lo;Narelle Skinner;Stephen Locarnini

  • Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition.

    Michelle D. Tate;Michelle D. Tate;James D. H. Ong;James D. H. Ong;Jennifer K. Dowling;Jennifer K. Dowling;Julie L. McAuley

  • Evaluation of inflammation and follicle depletion during ovarian ageing in mice.

    Carolina Lliberos;Seng H. Liew;Pirooz Zareie;Nicole L. La Gruta

  • Toll/IL-1 Signaling Is Critical for House Dust Mite–specific Th1 and Th2 Responses

    Simon Phipps;Chuan En Lam;Gerard E Kaiko;Shen Yun Foo

  • Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo.

    Jessica D. Cecil;Neil M O'Brien-Simpson;Jason C Lenzo;James A Holden

  • Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice.

    S M Krishnan;J K Dowling;Y H Ling;H Diep

  • Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation

    Tali Lang;Jacinta P. W. Lee;Kirstin Elgass;Anita A. Pinar

  • Mal Interacts with Tumor Necrosis Factor Receptor-associated Factor (TRAF)-6 to mediate NF-κB Activation by Toll-like Receptor (TLR)-2 and TLR4

    Ashley Scott Mansell;Ashley Scott Mansell;Elizabeth Brint;Jodee Ann Gould;Luke O'Neill

Frequent Co-Authors

Eicke Latz
Eicke Latz German Rheumatism Research Centre
Paul J. Hertzog
Paul J. Hertzog Hudson Institute of Medical Research
Grant R. Drummond
Grant R. Drummond La Trobe University
Bostjan Kobe
Bostjan Kobe University of Queensland
Luke A. J. O'Neill
Luke A. J. O'Neill Trinity College Dublin
Christopher G. Sobey
Christopher G. Sobey La Trobe University
Brendan J. Jenkins
Brendan J. Jenkins Hudson Institute of Medical Research
Matthew J. Sweet
Matthew J. Sweet University of Queensland
Mark E. Cooper
Mark E. Cooper Monash University
Richard L. Ferrero
Richard L. Ferrero Hudson Institute of Medical Research

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