D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 131 Citations 77,041 300 World Ranking 167 National Ranking 123
Medicine D-index 99 Citations 48,815 201 World Ranking 3838 National Ranking 2176

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cytokine

His primary scientific interests are in Receptor, TLR4, Toll-like receptor, Cell biology and Innate immune system. His Receptor research incorporates elements of Inflammation, Macrophage, Microbiology and Monocyte. His TLR4 research is under the purview of Signal transduction.

The concepts of his Toll-like receptor study are interwoven with issues in TLR2 and Protein kinase A. His Cell biology research is multidisciplinary, relying on both Secretion, Knockout mouse and Cytokine. Douglas T. Golenbock is investigating Innate immune system as part of his Immunology and Immune system and Innate immune system study.

His most cited work include:

  • Neuroinflammation in Alzheimer's disease (2213 citations)
  • IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. (1998 citations)
  • Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction * (1648 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Cell biology, Immunology, Receptor, Innate immune system and TLR4. Signal transduction is the focus of his Cell biology research. His Receptor study frequently draws connections to other fields, such as Macrophage.

His work deals with themes such as Immunity and Virology, which intersect with Innate immune system. His TLR4 study combines topics from a wide range of disciplines, such as Golgi apparatus, Secretion, Cancer research and Toll-like receptor. His CD14 study deals with Chinese hamster ovary cell intersecting with Transfection.

He most often published in these fields:

  • Cell biology (34.40%)
  • Immunology (33.53%)
  • Receptor (31.20%)

What were the highlights of his more recent work (between 2012-2021)?

  • Immunology (33.53%)
  • Innate immune system (27.99%)
  • Inflammasome (9.91%)

In recent papers he was focusing on the following fields of study:

Douglas T. Golenbock mostly deals with Immunology, Innate immune system, Inflammasome, Cell biology and Inflammation. His work investigates the relationship between Immunology and topics such as Disease that intersect with problems in Caspase 8. His study with Innate immune system involves better knowledge in Immune system.

Douglas T. Golenbock has included themes like Receptor, Transcriptome, Downregulation and upregulation and AIM2 in his Cell biology study. His Receptor study incorporates themes from DNA and Virology. His research investigates the connection between IRF3 and topics such as Toll-like receptor that intersect with issues in TLR2.

Between 2012 and 2021, his most popular works were:

  • Neuroinflammation in Alzheimer's disease (2213 citations)
  • NLRP3 is activated in Alzheimer´s disease and contributes to pathology in APP/PS1 mice (1205 citations)
  • The History of Toll-like Receptors - Redefining Innate Immunity (978 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Bacteria

Douglas T. Golenbock mainly investigates Innate immune system, Inflammasome, Immunology, Inflammation and Neuroinflammation. His study in Innate immune system is interdisciplinary in nature, drawing from both Proinflammatory cytokine, Nucleic acid and Virology. His Inflammasome study combines topics in areas such as Phagocytosis and Cell biology.

The study incorporates disciplines such as Cancer research, Hemozoin and AIM2 in addition to Cell biology. His Inflammation research is multidisciplinary, incorporating elements of Biochemistry and Bioinformatics. His work focuses on many connections between Signal transduction and other disciplines, such as DNA, that overlap with his field of interest in Microbiology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Neuroinflammation in Alzheimer's disease

Michael T Heneka;Monica J Carson;Joseph El Khoury;Gary E Landreth.
Lancet Neurology (2015)

2849 Citations

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

Katherine A. Fitzgerald;Sarah M. McWhirter;Kerrie L. Faia;Daniel C. Rowe.
Nature Immunology (2003)

2703 Citations

Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction *

Jesse C. Chow;Donna W. Young;Douglas T. Golenbock;William J. Christ.
Journal of Biological Chemistry (1999)

2299 Citations

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.

Annett Halle;Veit Hornung;Gabor C Petzold;Cameron R Stewart.
Nature Immunology (2008)

2026 Citations

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.

Evelyn A. Kurt-Jones;Evelyn A. Kurt-Jones;Lana Popova;Laura Kwinn;Lia M. Haynes.
Nature Immunology (2000)

2021 Citations

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

Eicke Latz;Annett Schoenemeyer;Alberto Visintin;Katherine A. Fitzgerald.
Nature Immunology (2004)

1546 Citations

NLRP3 is activated in Alzheimer´s disease and contributes to pathology in APP/PS1 mice

Michael T. Heneka;Markus P. Kummer;Andrea Stutz;Andrea Delekate.
Nature (2013)

1521 Citations

The History of Toll-like Receptors - Redefining Innate Immunity

Luke A. J. O'Neill;Douglas Golenbock;Andrew G. Bowie.
Nature Reviews Immunology (2013)

1509 Citations

Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2

Atsutoshi Yoshimura;Egil Lien;Robin R. Ingalls;Elaine Tuomanen.
Journal of Immunology (1999)

1494 Citations

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF

Katherine A. Fitzgerald;Daniel C. Rowe;Betsy J. Barnes;Daniel R. Caffrey.
Journal of Experimental Medicine (2003)

1436 Citations

Best Scientists Citing Douglas T. Golenbock

Shizuo Akira

Shizuo Akira

Osaka University

Publications: 348

Eicke Latz

Eicke Latz

University of Bonn

Publications: 189

Mihai G. Netea

Mihai G. Netea

Radboud University Nijmegen

Publications: 154

Katherine A. Fitzgerald

Katherine A. Fitzgerald

University of Massachusetts Medical School

Publications: 132

Luke A. J. O'Neill

Luke A. J. O'Neill

Trinity College Dublin

Publications: 114

Ricardo T. Gazzinelli

Ricardo T. Gazzinelli

Universidade de São Paulo

Publications: 114

Stefanie N. Vogel

Stefanie N. Vogel

University of Maryland, Baltimore

Publications: 104

Kensuke Miyake

Kensuke Miyake

University of Tokyo

Publications: 102

Osamu Takeuchi

Osamu Takeuchi

Kyoto University

Publications: 86

Leo A. B. Joosten

Leo A. B. Joosten

Radboud University Nijmegen

Publications: 83

Kiyoshi Takeda

Kiyoshi Takeda

Osaka University

Publications: 79

Tsukasa Seya

Tsukasa Seya

Hokkaido University

Publications: 79

Bruce Beutler

Bruce Beutler

The University of Texas Southwestern Medical Center

Publications: 76

Michael T. Heneka

Michael T. Heneka

German Center for Neurodegenerative Diseases

Publications: 76

Tom van der Poll

Tom van der Poll

University of Amsterdam

Publications: 75

Carsten J. Kirschning

Carsten J. Kirschning

University of Duisburg-Essen

Publications: 75

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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