World's Best Scientists 2026 revealed!
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Immunology
USA
2026

D-Index & Metrics

Immunology

D-Index
145
Citations
93657
World Ranking
138
National Ranking
91

Medicine

D-Index
145
Citations
93650
World Ranking
1371
National Ranking
797

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Immunology in United States Leader Award
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Douglas T. Golenbock is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a significant focus on several specialized subfields, including Immunology, Molecular Biology, Public Health, Environmental and Occupational Health, Infectious Diseases, and Parasitology.

The scientist's research covers multiple topics, notably:

  • Malaria Research and Control
  • Immune Response and Inflammation
  • Interferon and immune responses
  • Inflammasome and immune disorders
  • Mosquito-borne diseases and control
  • RNA and protein synthesis mechanisms
  • HIV Research and Treatment

Douglas T. Golenbock has contributed to numerous peer-reviewed publications. Some of their recent papers include:

  • "Immediate and long-term consequences of COVID-19 infections for the development of neurological disease," 2020, published in Alzheimer's Research & Therapy
  • "Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors," 2020, published in JCI Insight
  • "The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways," 2022, published in Cell Reports
  • "Itaconate impairs immune control of Plasmodium by enhancing mtDNA-mediated PD-L1 expression in monocyte-derived dendritic cells," 2024, published in Cell Metabolism
  • "Asymptomatic Plasmodium vivax malaria in the Brazilian Amazon: Submicroscopic parasitemic blood infects Nyssorhynchus darlingi," 2021, published in PLoS neglected tropical diseases

The main publication venues for their research include:

  • PLoS neglected tropical diseases
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Nature Communications
  • Nature Immunology

Douglas T. Golenbock frequently collaborates with several coauthors within their field. These include Ricardo T. Gazzinelli, Katherine A. Fitzgerald, Danielle Fernandes Durso, Evelyn A. Kurt-Jones, and Michael T. Heneka.

Among their professional recognitions, Douglas T. Golenbock has been named a Member of the Association of American Physicians.

Best Publications

  • Neuroinflammation in Alzheimer's disease

    Michael T Heneka;Monica J Carson;Joseph El Khoury;Gary E Landreth

  • IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

    Katherine A. Fitzgerald;Sarah M. McWhirter;Kerrie L. Faia;Daniel C. Rowe

  • NLRP3 is activated in Alzheimer´s disease and contributes to pathology in APP/PS1 mice

    Michael T. Heneka;Markus P. Kummer;Andrea Stutz;Andrea Delekate

  • The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.

    Annett Halle;Veit Hornung;Gabor C Petzold;Cameron R Stewart

  • Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction *

    Jesse C. Chow;Donna W. Young;Douglas T. Golenbock;William J. Christ

  • Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.

    Evelyn A. Kurt-Jones;Lana Popova;Laura Kwinn;Lia M. Haynes

  • The History of Toll-like Receptors - Redefining Innate Immunity

    Luke A. J. O'Neill;Douglas Golenbock;Andrew G. Bowie

  • CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

    Cameron R Stewart;Lynda M Stuart;Kim Wilkinson;Janine M van Gils

  • TLR9 signals after translocating from the ER to CpG DNA in the lysosome

    Eicke Latz;Annett Schoenemeyer;Alberto Visintin;Katherine A. Fitzgerald

  • Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.

    Jane Tian;Ana Maria Avalos;Su-Yau Mao;Bo Chen

  • LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF

    Katherine A. Fitzgerald;Daniel C. Rowe;Betsy J. Barnes;Daniel R. Caffrey

  • Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2

    Atsutoshi Yoshimura;Egil Lien;Robin R. Ingalls;Elaine Tuomanen

  • NLRP3 inflammasome activation drives tau pathology

    Christina Ising;Carmen Venegas;Shuangshuang Zhang;Hannah Scheiblich

  • TOLL-LIKE RECEPTOR 2 FUNCTIONS AS A PATTERN RECOGNITION RECEPTOR FOR DIVERSE BACTERIAL PRODUCTS

    Egil Lien;Egil Lien;Timothy J. Sellati;Atsutoshi Yoshimura;Trude H. Flo

  • Human Toll-Like Receptors Mediate Cellular Activation by Mycobacterium tuberculosis

    Terry K. Means;Shuyan Wang;Egil Lien;Atsutoshi Yoshimura

  • Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

    Chun-Jen Chen;Hajime Kono;Douglas Golenbock;George Reed

  • Human lupus autoantibody–DNA complexes activate DCs through cooperation of CD32 and TLR9

    Terry K. Means;Eicke Latz;Fumitaka Hayashi;Mandakolathur R. Murali

  • HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.

    Man Yu;Haichao Wang;Aihao Ding;Douglas T Golenbock

  • Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

    Carmen Venegas;Sathish Kumar;Bernardo S. Franklin;Tobias Dierkes

  • CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

    Frederick J Sheedy;Alena Grebe;Katey J Rayner;Parisa Kalantari

  • Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide

    Egil Lien;Terry K. Means;Holger Heine;Atsutoshi Yoshimura

Frequent Co-Authors

Eicke Latz
Eicke Latz German Rheumatism Research Centre
Ricardo T. Gazzinelli
Ricardo T. Gazzinelli Universidade Federal de Minas Gerais
Katherine A. Fitzgerald
Katherine A. Fitzgerald University of Massachusetts Chan Medical School
Egil Lien
Egil Lien University of Massachusetts Chan Medical School
Terje Espevik
Terje Espevik Norwegian University of Science and Technology
Evelyn A. Kurt-Jones
Evelyn A. Kurt-Jones University of Massachusetts Chan Medical School
Michael T. Heneka
Michael T. Heneka University Hospital Bonn
Shizuo Akira
Shizuo Akira Osaka University
Matthew J. Fenton
Matthew J. Fenton National Institute of Allergy and Infectious Diseases
Robert W. Finberg
Robert W. Finberg University of Massachusetts Chan Medical School

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