Member of the Association of American Physicians
His primary scientific interests are in Receptor, TLR4, Toll-like receptor, Cell biology and Innate immune system. His Receptor research incorporates elements of Inflammation, Macrophage, Microbiology and Monocyte. His TLR4 research is under the purview of Signal transduction.
The concepts of his Toll-like receptor study are interwoven with issues in TLR2 and Protein kinase A. His Cell biology research is multidisciplinary, relying on both Secretion, Knockout mouse and Cytokine. Douglas T. Golenbock is investigating Innate immune system as part of his Immunology and Immune system and Innate immune system study.
His primary areas of study are Cell biology, Immunology, Receptor, Innate immune system and TLR4. Signal transduction is the focus of his Cell biology research. His Receptor study frequently draws connections to other fields, such as Macrophage.
His work deals with themes such as Immunity and Virology, which intersect with Innate immune system. His TLR4 study combines topics from a wide range of disciplines, such as Golgi apparatus, Secretion, Cancer research and Toll-like receptor. His CD14 study deals with Chinese hamster ovary cell intersecting with Transfection.
Douglas T. Golenbock mostly deals with Immunology, Innate immune system, Inflammasome, Cell biology and Inflammation. His work investigates the relationship between Immunology and topics such as Disease that intersect with problems in Caspase 8. His study with Innate immune system involves better knowledge in Immune system.
Douglas T. Golenbock has included themes like Receptor, Transcriptome, Downregulation and upregulation and AIM2 in his Cell biology study. His Receptor study incorporates themes from DNA and Virology. His research investigates the connection between IRF3 and topics such as Toll-like receptor that intersect with issues in TLR2.
Douglas T. Golenbock mainly investigates Innate immune system, Inflammasome, Immunology, Inflammation and Neuroinflammation. His study in Innate immune system is interdisciplinary in nature, drawing from both Proinflammatory cytokine, Nucleic acid and Virology. His Inflammasome study combines topics in areas such as Phagocytosis and Cell biology.
The study incorporates disciplines such as Cancer research, Hemozoin and AIM2 in addition to Cell biology. His Inflammation research is multidisciplinary, incorporating elements of Biochemistry and Bioinformatics. His work focuses on many connections between Signal transduction and other disciplines, such as DNA, that overlap with his field of interest in Microbiology.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Neuroinflammation in Alzheimer's disease
Michael T Heneka;Monica J Carson;Joseph El Khoury;Gary E Landreth.
Lancet Neurology (2015)
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.
Katherine A. Fitzgerald;Sarah M. McWhirter;Kerrie L. Faia;Daniel C. Rowe.
Nature Immunology (2003)
Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction *
Jesse C. Chow;Donna W. Young;Douglas T. Golenbock;William J. Christ.
Journal of Biological Chemistry (1999)
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Annett Halle;Veit Hornung;Gabor C Petzold;Cameron R Stewart.
Nature Immunology (2008)
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.
Evelyn A. Kurt-Jones;Evelyn A. Kurt-Jones;Lana Popova;Laura Kwinn;Lia M. Haynes.
Nature Immunology (2000)
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
Eicke Latz;Annett Schoenemeyer;Alberto Visintin;Katherine A. Fitzgerald.
Nature Immunology (2004)
NLRP3 is activated in Alzheimer´s disease and contributes to pathology in APP/PS1 mice
Michael T. Heneka;Markus P. Kummer;Andrea Stutz;Andrea Delekate.
The History of Toll-like Receptors - Redefining Innate Immunity
Luke A. J. O'Neill;Douglas Golenbock;Andrew G. Bowie.
Nature Reviews Immunology (2013)
Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2
Atsutoshi Yoshimura;Egil Lien;Robin R. Ingalls;Elaine Tuomanen.
Journal of Immunology (1999)
LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF
Katherine A. Fitzgerald;Daniel C. Rowe;Betsy J. Barnes;Daniel R. Caffrey.
Journal of Experimental Medicine (2003)
Profile was last updated on December 6th, 2021.
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