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Immunology

D-Index
72
Citations
17561
World Ranking
2230
National Ranking
59

Overview

Dominik Hartl is affiliated with Novartis in Switzerland and has a research focus spanning immunology, medicine, and pharmaceutical economics. Their work appears predominantly in the fields of Immunology and Microbiology and Medicine, with notable contributions to subfields such as Immunology, Economics and Econometrics, Public Health, Environmental and Occupational Health, Pulmonary and Respiratory Medicine, and Oncology.

The scientist's primary research topics include:

  • Immune cells in cancer
  • Immune Response and Inflammation
  • Inflammation biomarkers and pathways
  • Pharmaceutical Economics and Policy
  • Biotechnology and Related Fields
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Psoriasis: Treatment and Pathogenesis

Recent publications by Dominik Hartl cover various aspects of immune regulation, inflammation, and the pharmaceutical industry. Key papers include:

  • Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis, 2020, Nature Communications
  • Regulatory Immune Cells in Idiopathic Pulmonary Fibrosis: Friends or Foes?, 2021, Frontiers in Immunology
  • Myeloid-Derived Suppressor Cells as a Potential Biomarker and Therapeutic Target in COVID-19, 2021, Frontiers in Immunology
  • Myeloid-Derived Suppressor Cells Dampen Airway Inflammation Through Prostaglandin E2 Receptor 4, 2021, Frontiers in Immunology
  • The significance of blockbusters in the pharmaceutical industry, 2022, Nature Reviews Drug Discovery

Dominik Hartl's frequent coauthors, representing collaborative efforts in research, include:

  • Alexander Schuhmacher
  • Chiel van Geffen
  • Astrid Deißler
  • Saeed Kolahian
  • Markus Hinder

Publications are regularly found in several scientific journals, including:

  • Frontiers in Immunology
  • Drug Discovery Today
  • Nature Communications
  • Nature Reviews Drug Discovery
  • Experimental Dermatology

Dominik Hartl's research integrates cellular immunology with clinical and pharmaceutical perspectives, addressing immune mechanisms in diseases such as psoriasis, idiopathic pulmonary fibrosis, and COVID-19, alongside investigations into pharmaceutical market dynamics.

Best Publications

  • Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

    Michael S D Kormann;Günther Hasenpusch;Manish K Aneja;Gabriela Nica

  • Neutrophils: Between host defence, immune modulation, and tissue injury

    Philipp Kruger;Mona Saffarzadeh;Alexander N. R. Weber;Nikolaus Rieber

  • Quantitative and functional impairment of pulmonary CD4+CD25hi regulatory T cells in pediatric asthma

    Dominik Hartl;Barbara Koller;Alexander T. Mehlhorn;Dietrich Reinhardt

  • Inflammation in cystic fibrosis lung disease: Pathogenesis and therapy

    André M. Cantin;Dominik Hartl;Michael W. Konstan;James F. Chmiel

  • Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13–induced tissue responses and apoptosis

    Chun Geun Lee;Dominik Hartl;Gap Ryol Lee;Barbara Koller

  • Chitin regulation of immune responses: an old molecule with new roles.

    Chun Geun Lee;Carla A Da Silva;Jae-Young Lee;Dominik Hartl

  • Immune Mechanisms in Pulmonary Fibrosis

    Saeed Kolahian;Isis E. Fernandez;Oliver Eickelberg;Dominik Hartl;Dominik Hartl

  • Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease.

    Dominik Hartl;Dominik Hartl;Philipp Latzin;Peter Hordijk;Veronica Marcos

  • NETs formed by human neutrophils inhibit growth of the pathogenic mold Aspergillus fumigatus.

    Allison McCormick;Leonie Heesemann;Johannes Wagener;Veronica Marcos

  • Chitin is a size-dependent regulator of macrophage TNF and IL-10 production.

    Carla A. Da Silva;Cécile Chalouni;Adam Williams;Dominik Hartl

  • TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.

    Carla A. Da Silva;Dominik Hartl;Wei Liu;Chun G. Lee

  • Infiltrated Neutrophils Acquire Novel Chemokine Receptor Expression and Chemokine Responsiveness in Chronic Inflammatory Lung Diseases

    Dominik Hartl;Susanne Krauss-Etschmann;Barbara Koller;Peter L. Hordijk

  • Innate immunity in cystic fibrosis lung disease

    D. Hartl;A. Gaggar;E. Bruscia;A. Hector

  • CFTR: cystic fibrosis and beyond

    Marcus A. Mall;Dominik Hartl

  • CXCR2 mediates NADPH oxidase–independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation

    Veronica Marcos;Zhe Zhou;Ali Önder Yildirim;Alexander Bohla

  • Pulmonary TH2 response in Pseudomonas aeruginosa–infected patients with cystic fibrosis

    Dominik Hartl;Matthias Griese;Matthias Kappler;Gernot Zissel

  • Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis.

    Franziska Herster;Zsofia Bittner;Nathan K. Archer;Sabine Dickhöfer

  • alpha1-Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients.

    M. Griese;P. Latzin;M. Kappler;K. Weckerle

  • Cellular Innate Immunity: An Old Game with New Players.

    Georg Gasteiger;Andrea D'osualdo;David A. Schubert;Alexander N. Weber

  • Ultrastructural characterization of cystic fibrosis sputum using atomic force and scanning electron microscopy.

    Reinhard Manzenreiter;Ferry Kienberger;Veronica Marcos;Kurt Schilcher

  • Toll-like receptor heterodimer variants protect from childhood asthma

    Michael S.D. Kormann;Martin Depner;Dominik Hartl;Norman Klopp

Frequent Co-Authors

Rupert Handgretinger
Rupert Handgretinger University of Tübingen
Jack A. Elias
Jack A. Elias Brown University
Chun Geun Lee
Chun Geun Lee Brown University
Marcus A. Mall
Marcus A. Mall Charité - University Medicine Berlin
Bernd H. Belohradsky
Bernd H. Belohradsky Ludwig-Maximilians-Universität München
Dirk Roos
Dirk Roos University of Amsterdam
Robert J. Homer
Robert J. Homer Yale University
Amit Gaggar
Amit Gaggar University of Alabama at Birmingham
Bernd Nürnberg
Bernd Nürnberg University of Tübingen
Fabian J. Theis
Fabian J. Theis Technical University of Munich

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