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D-Index & Metrics

Immunology

D-Index
78
Citations
20269
World Ranking
1762
National Ranking
868

Overview

Chun Geun Lee is affiliated with Brown University in the United States and has contributed extensively to biomedical research, particularly in the fields of medicine and biochemistry, genetics, and molecular biology. Their work centers around molecular biology, pulmonary and respiratory medicine, immunology, oncology, and infectious diseases.

The scientist's research emphasizes several main topics, including:

  • Studies on Chitinases and Chitosanases
  • Peptidase Inhibition and Analysis
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Invertebrate Immune Response Mechanisms
  • Mosquito-borne diseases and control
  • Extracellular vesicles in disease
  • Chronic Obstructive Pulmonary Disease (COPD) Research

Some of the recent papers authored or co-authored by Chun Geun Lee include:

  • The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer, 2023, Immunity
  • Potential role of chitinase-3-like protein 1 (CHI3L1/YKL-40) in neurodegeneration and Alzheimer's disease, 2022, Alzheimer's & Dementia
  • CHI3L1 regulates PD-L1 and anti-CHI3L1-PD-1 antibody elicits synergistic antitumor responses, 2021, Journal of Clinical Investigation
  • Chi3l1 Is a Modulator of Glioma Stem Cell States and a Therapeutic Target in Glioblastoma, 2023, Cancer Research
  • Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment, 2021, eLife

The scientist often collaborates with other researchers. Frequent co-authors include:

  • Jack A. Elias
  • Suchitra Kamle
  • Bing Ma
  • Chang-Min Lee
  • Bedia Akosman

Chun Geun Lee's publication record highlights a pattern of contributions to several key scientific journals, with multiple works appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Respiratory Cell and Molecular Biology
  • eLife
  • Science Advances
  • Journal of Clinical Investigation

Best Publications

  • Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1

    Chun Geun Lee;Robert J. Homer;Zhou Zhu;Sophie Lanone

  • Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury.

    Chun Geun Lee;Carla A. Da Silva;Charles S. Dela Cruz;Farida Ahangari

  • Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung.

    Chun Geun Lee;Holger Link;Peter Baluk;Robert J Homer

  • A Chitinase-like Protein in the Lung and Circulation of Patients with Severe Asthma

    Geoffrey L Chupp;Chun Geun Lee;Nizar Jarjour;Yun Michael Shim

  • New insights into the pathogenesis of asthma

    Jack A. Elias;Chun Geun Lee;Tao Zheng;Bing Ma

  • Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13–induced tissue responses and apoptosis

    Chun Geun Lee;Dominik Hartl;Gap Ryol Lee;Barbara Koller

  • Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle.

    Eun-Gyoung Hong;Hwi Jin Ko;Hwi Jin Ko;You-Ree Cho;You-Ree Cho;Hyo-Jeong Kim;Hyo-Jeong Kim

  • Early Growth Response Gene 1–mediated Apoptosis Is Essential for Transforming Growth Factor β1–induced Pulmonary Fibrosis

    Chun Geun Lee;Soo Jung Cho;Min Jong Kang;Svetlana P. Chapoval

  • Chitin regulation of immune responses: an old molecule with new roles.

    Chun Geun Lee;Carla A Da Silva;Jae-Young Lee;Dominik Hartl

  • Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13–induced inflammation and remodeling

    Sophie Lanone;Tao Zheng;Zhou Zhu;Wei Liu

  • Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death

    Vineet Bhandari;Rayman Choo-Wing;Chun G Lee;Zhou Zhu

  • Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2

    Chuan Hua He;Chun Geun Lee;Charles S. Dela Cruz;Chang-Min Lee

  • Chitinases and chitinase-like proteins in TH2 inflammation and asthma

    Jack A. Elias;Robert J. Homer;Qutayba Hamid;Chun Geun Lee

  • Chitin is a size-dependent regulator of macrophage TNF and IL-10 production.

    Carla A. Da Silva;Cécile Chalouni;Adam Williams;Dominik Hartl

  • TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.

    Carla A. Da Silva;Dominik Hartl;Wei Liu;Chun G. Lee

  • Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice.

    Min-Jong Kang;Chun Geun Lee;Jae-Young Lee;Charles S. Dela Cruz

  • Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling.

    Zhou Zhu;Tao Zheng;Chun G Lee;Robert J Homer

  • Semaphorin 7A plays a critical role in TGF-β1–induced pulmonary fibrosis

    Hye-Ryun Kang;Chun Geun Lee;Robert J. Homer;Jack A. Elias

  • IL-13-induced chemokine responses in the lung: Role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling

    Zhou Zhu;Bing Ma;Tao Zheng;Robert J. Homer;Robert J. Homer

  • Transforming Growth Factor (TGF)-β1 Stimulates Pulmonary Fibrosis and Inflammation via a Bax-dependent, Bid-activated Pathway That Involves Matrix Metalloproteinase-12

    Hye-Ryun Kang;Soo Jung Cho;Chun Geun Lee;Robert J. Homer

Frequent Co-Authors

Jack A. Elias
Jack A. Elias Brown University
Robert J. Homer
Robert J. Homer Yale University
Charles S. Dela Cruz
Charles S. Dela Cruz Yale University
Zhou Zhu
Zhou Zhu Brown University
Dominik Hartl
Dominik Hartl Novartis (Switzerland)
Richard A. Flavell
Richard A. Flavell Yale University
Patty J. Lee
Patty J. Lee Duke University
Augustine M. K. Choi
Augustine M. K. Choi Cornell University
Anthony J. Coyle
Anthony J. Coyle Takeda (United States)
Harold A. Singer
Harold A. Singer Albany Medical Center Hospital

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