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Francis J. Castellino

Francis J. Castellino

University of Notre Dame
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
83
Citations
25036
World Ranking
3492
National Ranking
1754

Francis J. Castellino publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Francis J. Castellino sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 533 publications — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Francis J. Castellino D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Francis J. Castellino sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 83 D-Index — 83rd percentile

83% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Francis J. Castellino is affiliated with the University of Notre Dame in the United States. Their research predominantly lies in the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on subfields such as Public Health, Environmental and Occupational Health, Molecular Biology, Infectious Diseases, Clinical Biochemistry, and Epidemiology.

The scientist has contributed extensively to research on various medical topics, particularly in Streptococcal infections and treatments. Other main topics of work include Neonatal and Maternal Infections, Bacterial Identification and Susceptibility Testing, Antimicrobial Resistance in Staphylococcus, Biochemical and Structural Characterization, Protease and Inhibitor Mechanisms, and Urinary Tract Infections Management.

Frequent coauthors of Francis J. Castellino include:

  • Victoria A. Ploplis (24 co-publications)
  • Yetunde A. Ayinuola (16 co-publications)
  • Shaun W. Lee (14 co-publications)
  • Deborah L. Donahue (11 co-publications)
  • Zhong Liang (10 co-publications)

They have published multiple papers across notable scientific journals and venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory) with 7 publications
  • Journal of Biological Chemistry with 4 publications
  • Journal of Bacteriology with 2 publications
  • Frontiers in Cardiovascular Medicine with 2 publications
  • Current Drug Targets with 2 publications

Recent papers by Francis J. Castellino include:

  • Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier (2021, Science)
  • The Streptococcal Protease SpeB Antagonizes the Biofilms of the Human Pathogen Staphylococcus aureus USA300 through Cleavage of the Staphylococcal SdrC Protein (2020, Journal of Bacteriology)
  • In situ metabolite and lipid analysis of GluN2D−/− and wild-type mice after ischemic stroke using MALDI MSI (2020, Analytical and Bioanalytical Chemistry)
  • Synthetic Antimicrobial Peptide Tuning Permits Membrane Disruption and Interpeptide Synergy (2020, ACS Pharmacology & Translational Science)
  • Altered Smooth Muscle Cell Histone Acetylome by the SPHK2/S1P Axis Promotes Pulmonary Hypertension (2023, Circulation Research)

Best Publications

  • Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective.

    Tong Cheng;Dong Liu;John H. Griffin;José A. Fernández

  • Exosomes released from macrophages infected with intracellular pathogens stimulate a proinflammatory response in vitro and in vivo

    Sanchita Bhatnagar;Kazuhiko Shinagawa;Francis J. Castellino;Jeffrey S. Schorey

  • Structure and function of the plasminogen/plasmin system.

    Francis J. Castellino;Victoria A. Ploplis

  • Measurement of the binding of antifibrinolytic amino acids to various plasminogens

    William J. Brockway;Francis J. Castellino

  • Glycosylation of Pichia pastoris-derived proteins.

    Roger K. Bretthauer;Francis J. Castellino

  • The Complete Amino Acid Sequence of Bovine α-Lactalbumin

    Keith Brew;Francis J. Castellino;Thomas C. Vanaman;Robert L. Hill

  • The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin

    S Gately;P Twardowski;M S Stack;D L Cundiff

  • Early platelet dysfunction: an unrecognized role in the acute coagulopathy of trauma.

    Max V. Wohlauer;Ernest E. Moore;Ernest E. Moore;Scott Thomas;Scott Thomas;Angela Sauaia

  • Endotoxemia and sepsis mortality reduction by non-anticoagulant–activated protein C

    Edward J. Kerschen;José A. Fernandez;Brian C. Cooley;Xia V. Yang

  • Tumor Development Is Retarded in Mice Lacking the Gene for Urokinase-Type Plasminogen Activator or Its Inhibitor, Plasminogen Activator Inhibitor-1

    Linda S. Gutierrez;Alexis Schulman;Teresa Brito-Robinson;Francisco Noria

  • [29] Human plasminogen

    Francis J. Castellino;James R. Powell

  • Mice lacking factor VII develop normally but suffer fatal perinatal bleeding

    Elliot D. Rosen;Joyce C. Y. Chan;Esohe Idusogie;Frédéric Clotman

  • The fibrin-derived peptide Bβ 15-42 protects the myocardium against ischemia-reperfusion injury

    Peter Petzelbauer;Paula A Zacharowski;Yasuhiro Miyazaki;Peter Friedl

  • Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice.

    Louise R. Jalbert;Elliot D. Rosen;Lieve Moons;Joyce C.Y. Chan;Joyce C.Y. Chan

  • Blood coagulation factor X deficiency causes partial embryonic lethality and fatal neonatal bleeding in mice.

    Mieke Dewerchin;Zhong Liang;Lieve Moons;Peter Carmeliet

  • FXI is essential for thrombus formation following FeCl3-induced injury of the carotid artery in the mouse.

    Elliot D. Rosen;Dave Gailani;Francis J. Castellino

  • Oligosaccharide processing in the expression of human plasminogen cDNA by lepidopteran insect (Spodoptera frugiperda) cells

    Donald J. Davidson;Malcolm J. Fraser;Francis J. Castellino

  • Characterization of kringle domains of angiostatin as antagonists of endothelial cell migration, an important process in angiogenesis

    Weidong-Richard Ji;Francis J. Castellino;Yuan Chang;Melanie E. Deford

  • The effect of alpha-,omega-amino acids on human plasminogen structure and activation.

    B N Violand;R Byrne;F J Castellino

  • Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells

    Zhihui Zhong;Hristelina Ilieva;Lee Hallagan;Robert Bell

Frequent Co-Authors

Peter Carmeliet
Peter Carmeliet KU Leuven
Lindsey A. Miles
Lindsey A. Miles Scripps Research Institute
John H. Griffin
John H. Griffin Scripps Research Institute
Desire Collen
Desire Collen KU Leuven
John G. Duman
John G. Duman University of Notre Dame
Ernest E. Moore
Ernest E. Moore University of Colorado Denver
José A. Fernández
José A. Fernández Scripps Research Institute
Dudley K. Strickland
Dudley K. Strickland American Red Cross
Lieve Moons
Lieve Moons KU Leuven
Berislav V. Zlokovic
Berislav V. Zlokovic University of Southern California

External Links

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Additionally, kinesiology online programs provide flexible pathways to roles focused on human movement, wellness, and therapeutic practices. These online degrees can accelerate your entry into specialized, rewarding careers allied closely to biology and biochemistry.

Best Scientists Citing Francis J. Castellino

Charles T. Esmon

Charles T. Esmon

Oklahoma Medical Research Foundation

Publications: 124

John H. Griffin

John H. Griffin

Scripps Research Institute

Publications: 103

Berislav V. Zlokovic

Berislav V. Zlokovic

University of Southern California

Publications: 62

Nigel Mackman

Nigel Mackman

University of North Carolina at Chapel Hill

Publications: 56

Salvatore V. Pizzo

Salvatore V. Pizzo

Duke University

Publications: 56

Wolfram Ruf

Wolfram Ruf

Johannes Gutenberg University of Mainz

Publications: 49

Alireza R. Rezaie

Alireza R. Rezaie

Oklahoma Medical Research Foundation

Publications: 48

José A. Fernández

José A. Fernández

Scripps Research Institute

Publications: 42

John G. Duman

John G. Duman

University of Notre Dame

Publications: 40

Tom van der Poll

Tom van der Poll

University of Amsterdam

Publications: 36

Bruce Furie

Bruce Furie

Beth Israel Deaconess Medical Center

Publications: 36

Lindsey A. Miles

Lindsey A. Miles

Scripps Research Institute

Publications: 35

Steven L. Gonias

Steven L. Gonias

University of California, San Diego

Publications: 35

Edward F. Plow

Edward F. Plow

Cleveland Clinic Lerner College of Medicine

Publications: 35

Peter Carmeliet

Peter Carmeliet

KU Leuven

Publications: 33

Desire Collen

Desire Collen

KU Leuven

Publications: 33

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