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Biology and Biochemistry

D-Index
51
Citations
10947
World Ranking
17066
National Ranking
7036

Overview

Lindsey A. Miles is affiliated with the Scripps Research Institute in the United States and has contributed extensively to research within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Cancer Research, Molecular Biology, Hematology, Epidemiology, and Immunology.

The main topics covered in Lindsey A. Miles's research include Protease and Inhibitor Mechanisms, Blood Coagulation and Thrombosis Mechanisms, S100 Proteins and Annexins, Blood properties and coagulation, Sepsis Diagnosis and Treatment, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, as well as Wound Healing and Treatments.

Recent publications by Lindsey A. Miles comprise:

  • Plasminogen Receptors and Fibrinolysis (2021, International Journal of Molecular Sciences)
  • Functions of the plasminogen receptor Plg-RKT (2020, Journal of Thrombosis and Haemostasis)
  • Plasmin and plasminogen prevent sepsis severity by reducing neutrophil extracellular traps and systemic inflammation (2023, JCI Insight)
  • The plasminogen receptor, Plg-RKT, plays a role in inflammation and fibrinolysis during cutaneous wound healing in mice (2020, Cell Death and Disease)
  • Exposure of plasminogen and a novel plasminogen receptor, Plg-RKT, on activated human and murine platelets (2020, Blood)

Frequently collaborating co-authors include Robert J. Parmer, Nagyung Baik, Lirlândia P. Sousa, Juliana P. Vago, and Luíza Oliveira Perucci.

Lindsey A. Miles's research has been published predominantly in journals such as the Journal of Thrombosis and Haemostasis, Blood, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Research and Practice in Thrombosis and Haemostasis, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • A potential basis for the thrombotic risks associated with lipoprotein(a).

    Lindsey A. Miles;Gunther M. Fless;Eugene G. Levin;Angelo M. Scanu

  • Role of cell-surface lysines in plasminogen binding to cells: identification of alpha-enolase as a candidate plasminogen receptor.

    Lindsey A. Miles;Carol M. Dahlberg;Janet Plescia;Jordi Felez

  • The plasminogen system and cell surfaces: evidence for plasminogen and urokinase receptors on the same cell type

    Edward E Plow;Doreen E. Freaney;Janet Plescia;Lindsey A. Miles

  • The cell biology of the plasminogen system.

    Edward F. Plow;Thomas Herren;Alexander Redlitz;Lindsey A. Miles

  • Elevated matrix metalloprotease and angiostatin levels in integrin α1 knockout mice cause reduced tumor vascularization

    Ambra Pozzi;Philip E. Moberg;Lindsey A. Miles;Simone Wagner

  • Binding and activation of plasminogen on the platelet surface.

    L A Miles;E F Plow

  • The role of an enolase-related molecule in plasminogen binding to cells.

    Alexander Redlitz;Bruce J. Fowler;Edward F. Plow;Lindsey A. Miles

  • Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells.

    Takehiko Tarui;Lindsey A. Miles;Yoshikazu Takada

  • Receptor mediated binding of the fibrinolytic components, plasminogen and urokinase, to peripheral blood cells.

    Lindsey A Miles;Edward F Plow

  • Plasminogen receptors: Ubiquitous sites for cellular regulation of fibrinolysis

    L.A. Miles;E.F. Plow

  • Cellular regulation of fibrinolysis.

    Edward F Plow;Jordi Felez;Lindsey A Miles

  • Plasminogen Receptors, Urokinase Receptors, and Their Modulation on Human Endothelial Cells

    Lindsey A. Miles;Eugene G. Levin;Janet Plescia;Desire Collen

  • Plasmin-induced migration of endothelial cells: A potential target for the anti-angiogenic action of angiostatin

    Takehiko Tarui;Mousumi Majumdar;Lindsey A. Miles;Wolfram Ruf

  • Tissue Plasminogen Activator (t-PA) Is Targeted to the Regulated Secretory Pathway CATECHOLAMINE STORAGE VESICLES AS A RESERVOIR FOR THE RAPID RELEASE OF t-PA

    Robert J. Parmer;Manjula Mahata;Sushil Mahata;Matthew T. Sebald;Matthew T. Sebald

  • The cell-binding domains of plasminogen and their function in plasma.

    L A Miles;C M Dahlberg;E F Plow

  • Plasminogen has a broad extrahepatic distribution.

    Lu Zhang;Dietmar Seiffert;Bruce J Fowler;George R Jenkins

  • Lp(a): an interloper into the fibrinolytic system?

    Lindsey A Miles;Edward F Plow

  • Plasminogen interacts with human platelets through two distinct mechanisms.

    L. A. Miles;M. H. Ginsberg;J. G. White;Edward F Plow

  • Proteomics-based discovery of a novel, structurally unique, and developmentally regulated plasminogen receptor, Plg-RKT, a major regulator of cell surface plasminogen activation

    Nicholas M. Andronicos;Emily I. Chen;Nagyung Baik;Hongdong Bai

  • Cellular regulation of fibrinolysis

    E.F. Plow

Frequent Co-Authors

Edward F. Plow
Edward F. Plow Cleveland Clinic Lerner College of Medicine
Francis J. Castellino
Francis J. Castellino University of Notre Dame
William B. Kiosses
William B. Kiosses La Jolla Institute For Allergy & Immunology
Daniel T. O'Connor
Daniel T. O'Connor University of California, San Diego
Angelo M. Scanu
Angelo M. Scanu University of Chicago
John H. Griffin
John H. Griffin Scripps Research Institute
Sushil K. Mahata
Sushil K. Mahata University of California, San Diego
Linda K. Curtiss
Linda K. Curtiss Scripps Research Institute
Barbara M. Mueller
Barbara M. Mueller Torrey Pines Institute For Molecular Studies
Tor Ny
Tor Ny Umeå University

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