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Salvatore V. Pizzo

Salvatore V. Pizzo

D-Index & Metrics

Chemistry

D-Index
88
Citations
24034
World Ranking
2329
National Ranking
831

Biology and Biochemistry

D-Index
95
Citations
28653
World Ranking
1931
National Ranking
1057

Medicine

D-Index
93
Citations
28163
World Ranking
10981
National Ranking
5646

Research.com Recognitions

  • 1999 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Salvatore V. Pizzo is affiliated with Duke University in the United States and has contributed extensively to the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research focuses notably on Molecular Biology, Cell Biology, Surgery, Epidemiology, and Cellular and Molecular Neuroscience, with a significant emphasis on the areas of Endoplasmic Reticulum Stress and Disease, Heat shock proteins research, and Autophagy in Disease and Therapy.

The scientist's recent publications include investigations into glucose-regulated protein 78 (GRP78) and its role in various pathological and physiological processes. Some key papers are:

  • Glucose-regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders, 2021, published in IUBMB Life
  • Cell surface GRP78 signaling: An emerging role as a transcriptional modulator in cancer, 2020, published in Journal of Cellular Physiology
  • Physiological Roles of the Autoantibodies to the 78-Kilodalton Glucose-Regulated Protein (GRP78) in Cancer and Autoimmune Diseases, 2022, published in Biomedicines
  • Activated α2-macroglobulin binding to cell surface GRP78 induces trophoblastic cell fusion, 2020, published in Scientific Reports
  • Pathologic Proteolytic Processing of N-Cadherin as a Marker of Human Fibrotic Disease, 2022, published in Cells

They frequently collaborate with other researchers, including Mario Gonzalez-Gronow, Paul Ferrell, Kristianne M. Oristian, Luis Sandoval, and Davin Sim. These collaborations have contributed to advancing knowledge in cancer biology, cellular signaling, and disease mechanisms.

Their work has been published in various scientific venues with multiple contributions in Biomedicines, Scientific Reports, UNC Libraries, Journal of the Endocrine Society, and IUBMB Life.

Salvatore V. Pizzo's research interests cover the following topics:

  • Endoplasmic Reticulum Stress and Disease
  • Heat shock proteins research
  • Autophagy in Disease and Therapy
  • Gestational Trophoblastic Disease Studies
  • Ubiquitin and proteasome pathways
  • Hereditary Neurological Disorders
  • Genetic and Kidney Cyst Diseases

In 1999, they were recognized as a Fellow of the American Association for the Advancement of Science (AAAS), highlighting their role in advancing scientific research.

Best Publications

  • Angiostatin binds ATP synthase on the surface of human endothelial cells

    Tammy L. Moser;M. Sharon Stack;Iain Asplin;Jan J. Enghild

  • Human Factor XIII from Plasma and Platelets MOLECULAR WEIGHTS, SUBUNIT STRUCTURES, PROTEOLYTIC ACTIVATION, AND CROSS-LINKING OF FIBRINOGEN AND FIBRIN

    Martin L. Schwartz;Salvatore V. Pizzo;Robert L. Hill;Patrick A. McKee

  • Clearance and binding of two electrophoretic “fast” forms of human alpha 2-macroglobulin.

    M J Imber;S V Pizzo

  • A new procedure for the synthesis of polyethylene glycol-protein adducts; effects on function, receptor recognition, and clearance of superoxide dismutase, lactoferrin, and alpha 2-macroglobulin.

    Charles O. Beauchamp;Charles O. Beauchamp;Steven L. Gonias;David P. Menapace;David P. Menapace;Salvatore V. Pizzo

  • The Effect of Plasmin on the Subunit Structure of Human Fibrin

    Salvatore V. Pizzo;Martin L. Schwartz;Robert L. Hill;Patrick A. McKee

  • Endothelial cell surface F1-FO ATP synthase is active in ATP synthesis and is inhibited by angiostatin

    Tammy L. Moser;Daniel J. Kenan;Timothy A. Ashley;Julie A. Roy

  • Mast cell-derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection.

    James B McLachlan;Justin P Hart;Salvatore V Pizzo;Christopher P Shelburne

  • Activation and Cross-talk between Akt, NF-κB, and Unfolded Protein Response Signaling in 1-LN Prostate Cancer Cells Consequent to Ligation of Cell Surface-associated GRP78

    Uma Kant Misra;Rohit Deedwania;Salvatore Vincent Pizzo

  • GRP78: a multifunctional receptor on the cell surface.

    Mario Gonzalez-Gronow;Maria Angelica Selim;John Papalas;Salvatore V Pizzo

  • Scavenger receptor-A mediates gp96/GRP94 and calreticulin internalization by antigen-presenting cells.

    Brent Berwin;Justin P. Hart;Stuart Rice;Cecilia Gass

  • Further characterization of the cellular plasminogen binding site: evidence that plasminogen 2 and lipoprotein a compete for the same site.

    Mario Gonzalez-Gronow;Jay M. Edelberg;Salvatore V. Pizzo

  • Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed, and reactive site cleaved serpins: comparison of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, antithrombin III, alpha 2-antiplasmin, angiotensinogen, and ovalbumin.

    Alan E. Mast;Jan J. Enghild;Salvatore V. Pizzo;Guy Salvesen

  • Effector mechanisms of cytolytically activated macrophages. II. Secretion of a cytolytic factor by activated macrophages and its relationship to secreted neutral proteases.

    D O Adams;K J Kao;R Farb;S V Pizzo

  • GRP78, A chaperone with diverse roles beyond the endoplasmic reticulum

    Quintin J Quinones;Gustaaf G de Ridder;Salvatore V Pizzo

  • Physical properties of human α2-macroglobulin following reaction with methylamine and trypsin

    Steven L. Gonias;Jacqueline A. Reynolds;Salvatore V. Pizzo

  • Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan.

    J J Enghild;I B Thøgersen;S V Pizzo;G Salvesen

  • Downregulation of microglial activation by apolipoprotein E and apoE-mimetic peptides.

    D.T. Laskowitz;A.D. Thekdi;S.D. Thekdi;S.K.D. Han

  • Relationship of sialic acid to function and in vivo survival of human factor VIII/von Willebrand factor protein.

    J M Sodetz;S V Pizzo;P A McKee

  • Binding of activated α2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMK

    Uma Kant Misra;Rohit Deedwania;Salvatore Vincent Pizzo

  • Mast cell activators: a new class of highly effective vaccine adjuvants

    James B McLachlan;Christopher P Shelburne;Justin P Hart;Salvatore V Pizzo

  • Demonstration and characterization of specific binding sites for factor VIII/von Willebrand factor on human platelets.

    K J Kao;S V Pizzo;P A McKee

Frequent Co-Authors

Steven L. Gonias
Steven L. Gonias University of California, San Diego
Jan J. Enghild
Jan J. Enghild Aarhus University
Stephen J. Freedland
Stephen J. Freedland Cedars-Sinai Medical Center
Guy S. Salvesen
Guy S. Salvesen Sanford Burnham Prebys Medical Discovery Institute
Paul A. Roche
Paul A. Roche National Institutes of Health
Steven R. Feldman
Steven R. Feldman Wake Forest University
Mark W. Dewhirst
Mark W. Dewhirst Duke University
Robert L. Hill
Robert L. Hill Duke University
M. Sharon Stack
M. Sharon Stack University of Notre Dame
Charleen T. Chu
Charleen T. Chu University of Pittsburgh

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