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Biology and Biochemistry

D-Index
84
Citations
56970
World Ranking
3226
National Ranking
1632

Overview

Charleen T. Chu is affiliated with the University of Pittsburgh in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a notable focus on Molecular Biology, Neurology, Radiology, Nuclear Medicine and Imaging, Ophthalmology, and Cellular and Molecular Neuroscience.

The main topics explored in Chu's work include Parkinson's Disease Mechanisms and Treatments, Mitochondrial Function and Pathology, Autophagy in Disease and Therapy, Corneal Surgery and Treatments, Intraocular Surgery and Lenses, Corneal Surgery and Disorders, and Alzheimer's disease research and treatments.

Chu has contributed to several recent papers characterized by their publication year and venues:

  • "Autophagy in major human diseases," 2021, published in The EMBO Journal
  • "Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration," 2022, published in Translational Neurodegeneration
  • "Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal," 2021, published in Nature Chemical Biology
  • "International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis," 2024, published in Autophagy
  • "Neuronal autophagy and mitophagy in Parkinson's disease," 2021, published in Molecular Aspects of Medicine

Frequent collaborators in Chu's research include:

  • Britney N. Lizama
  • Ken K. Nischal
  • Manish Verma
  • P. Anthony Otero
  • Hannah L. Scanga

Chu frequently publishes in the following venues:

  • Cornea
  • The FASEB Journal
  • Autophagy
  • American Journal of Ophthalmology Case Reports
  • American Journal Of Pathology

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Molecular definitions of autophagy and related processes

    Lorenzo Galluzzi;Lorenzo Galluzzi;Eric H. Baehrecke;Andrea Ballabio;Patricia Boya

  • Autophagy in major human diseases

    Daniel J. Klionsky;Giulia Petroni;Ravi K. Amaravadi;Eric H. Baehrecke

  • Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

    Charleen T. Chu;Jing Ji;Ruben K. Dagda;Jian Fei Jiang

  • Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission

    Ruben K. Dagda;Salvatore J. Cherra;Scott M. Kulich;Scott M. Kulich;Anurag Tandon

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Expression of Nrf2 in Neurodegenerative Diseases

    Chenere P. Ramsey;Charles A. Glass;Marshall B. Montgomery;Kathryn A. Lindl

  • α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease

    Roberto Di Maio;Paul J. Barrett;Eric K. Hoffman;Caitlyn W. Barrett

  • PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis

    Marta Bueno;Yen-Chun Lai;Yair Romero;Judith Brands

  • Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells.

    Edward D. Plowey;Salvatore J. Cherra;Yong-Jian Liu;Charleen T. Chu

  • Regulation of Autophagy by Extracellular Signal- Regulated Protein Kinases During 1-Methyl-4- Phenylpyridinium-Induced Cell Death

    Jian Hui Zhu;Craig Horbinski;Fengli Guo;Simon Watkins

  • A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

    Daniel J Klionsky;Eric H. Baehrecke;John H. Brumell;Charleen T. Chu

  • Regulation of the autophagy protein LC3 by phosphorylation

    Salvatore J. Cherra;Scott M. Kulich;Scott M. Kulich;Guy Uechi;Manimalha Balasubramani

  • Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease.

    Ruben K. Dagda;Jianhui Zhu;Scott M. Kulich;Charleen T. Chu

  • Oxidative neuronal injury: The dark side of ERK1/2

    Charleen T. Chu;David J. Levinthal;Scott M. Kulich;Elisabeth M. Chalovich

  • After the banquet: Mitochondrial biogenesis, mitophagy, and cell survival

    Jianhui Zhu;Kent Z Q Wang;Charleen T Chu

  • Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases.

    Jian-Hui Zhu;Fengli Guo;John Shelburne;Simon Watkins

Frequent Co-Authors

Hülya Bayır
Hülya Bayır University of Pittsburgh
Valerian E. Kagan
Valerian E. Kagan University of Pittsburgh
Salvatore V. Pizzo
Salvatore V. Pizzo Duke University
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Tim D. Oury
Tim D. Oury University of Pittsburgh
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine
Rama K. Mallampalli
Rama K. Mallampalli The Ohio State University
Eric H. Baehrecke
Eric H. Baehrecke University of Massachusetts Chan Medical School
Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Sergio Lavandero
Sergio Lavandero University of Chile

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