What is he best known for?
The fields of study he is best known for:
- Cell membrane
- Amino acid
- Genetics
His primary areas of investigation include Cell biology, Endosome, Sorting Nexins, Sorting nexin and SNX27.
His study in VPS29, Retromer complex, Retromer, Transport protein and Phosphatidylinositol is carried out as part of his Cell biology studies.
Peter J. Cullen focuses mostly in the field of VPS29, narrowing it down to matters related to VPS35 and, in some cases, LRP6, Wnt signaling pathway and Endosome membrane.
His work in Endosome addresses issues such as Golgi apparatus, which are connected to fields such as Mannose 6-phosphate, PLCG1 and Signal transduction.
His Sorting nexin research is multidisciplinary, relying on both Endocytic cycle and PX domain.
As a part of the same scientific family, Peter J. Cullen mostly works in the field of Molecular biology, focusing on Anti-apoptotic Ras signalling cascade and, on occasion, Second messenger system and Intracellular.
His most cited work include:
- Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase. (2887 citations)
- Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage. (513 citations)
- Sorting Nexin-1 Mediates Tubular Endosome-to-TGN Transport through Coincidence Sensing of High- Curvature Membranes and 3-Phosphoinositides (369 citations)
What are the main themes of his work throughout his whole career to date?
Peter J. Cullen spends much of his time researching Cell biology, Endosome, Retromer, Biochemistry and Inositol.
Cell biology is a component of his Sorting Nexins, Sorting nexin, Transport protein, Retromer complex and SNX27 studies.
His research in Sorting Nexins intersects with topics in Dynein and BAR domain.
His Endosome research incorporates themes from Integral membrane protein, Endocytic cycle, Clathrin and Transmembrane protein.
His work on GTPase-activating protein, Pleckstrin homology domain, Plasma protein binding and Microsome as part of general Biochemistry research is often related to Cytosol, thus linking different fields of science.
In his study, which falls under the umbrella issue of Inositol, Kinase and Guanine nucleotide exchange factor is strongly linked to Second messenger system.
He most often published in these fields:
- Cell biology (70.95%)
- Endosome (38.51%)
- Retromer (27.70%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (70.95%)
- Endosome (38.51%)
- Retromer (27.70%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cell biology, Endosome, Retromer, Sorting Nexins and Transmembrane protein.
Peter J. Cullen has researched Cell biology in several fields, including Membrane and Binding site.
His work in the fields of Endosome, such as Sorting nexin, overlaps with other areas such as Sorting.
Peter J. Cullen works mostly in the field of Retromer, limiting it down to topics relating to Extracellular and, in certain cases, Retromer complex.
His Sorting Nexins research is multidisciplinary, incorporating elements of Transport protein, Endocytic cycle and Autophagosome assembly.
His Transmembrane protein study incorporates themes from WASH complex, Structural biology, Membrane transport protein and Protein targeting.
Between 2017 and 2021, his most popular works were:
- Neuropilin-1 is a host factor for SARS-CoV-2 infection. (220 citations)
- To degrade or not to degrade: mechanisms and significance of endocytic recycling (129 citations)
- Endosomal Retrieval of Cargo: Retromer Is Not Alone. (59 citations)
In his most recent research, the most cited papers focused on:
- Cell membrane
- Amino acid
- Genetics
The scientist’s investigation covers issues in Cell biology, Endosome, Retromer, Transmembrane protein and Function.
His Cell biology study integrates concerns from other disciplines, such as Virus and Immunoprecipitation.
Peter J. Cullen combines subjects such as Integral membrane protein, Ion channel and Cell adhesion molecule with his study of Endosome.
The concepts of his Retromer study are interwoven with issues in Transport protein and Protein targeting.
His work focuses on many connections between Transmembrane protein and other disciplines, such as Sorting Nexins, that overlap with his field of interest in Endocytosis, A-site, BAR domain, Structural biology and Receptor recycling.
His studies in Function integrate themes in fields like Cell, Wnt signaling pathway, Transport Pathway, Phenocopy and Translocase.
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