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Biology and Biochemistry

D-Index
74
Citations
16004
World Ranking
5733
National Ranking
133

Overview

Paul A. Gleeson is affiliated with the University of Melbourne in Australia. Their research primarily focuses on topics related to cellular transport, secretion, and molecular mechanisms integral to cell biology and physiology.

The scientist's most frequent fields of study include Biochemistry, Genetics and Molecular Biology, with 64 publications, followed by Medicine, with 23 publications. Their subfields of study encompass Molecular Biology, Cell Biology, Physiology, Cancer Research, and Epidemiology. These disciplines contextualize their research within both fundamental biological processes and disease mechanisms.

Key areas of research covered by Paul A. Gleeson are as follows:

  • Cellular transport and secretion
  • Retinal Development and Disorders
  • Alzheimer's disease research and treatments
  • Autophagy in Disease and Therapy
  • Biomedical Research and Pathophysiology
  • PI3K/AKT/mTOR signaling in cancer
  • Advanced Glycation End Products research

Among their recent publications are:

  • "Macropinocytosis in Different Cell Types: Similarities and Differences," 2020, Membranes
  • "Sorting nexin 5 mediates virus-induced autophagy and immunity," 2020, Nature
  • "Regulation of mTORC1 activity by the Golgi apparatus," 2021, Faculty Reviews
  • "Local Secretory Trafficking Pathways in Neurons and the Role of Dendritic Golgi Outposts in Different Cell Models," 2020, Frontiers in Molecular Neuroscience
  • "BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking," 2024, Communications Biology

Frequent co-authors of Paul A. Gleeson include:

  • Lou Fourrière
  • Jingqi Wang
  • Fiona J. Houghton
  • Hyun-Jung Cho
  • Sharon Tran

The top publication venues where this scientist has contributed multiple works are:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Traffic
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Membranes
  • Nature

Best Publications

  • Macropinocytosis: an endocytic pathway for internalising large gulps

    Jet Phey Lim;Paul A Gleeson

  • Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking.

    M. J. Petris;J. F. B. Mercer;J. G. Culvenor;P. Lockhart

  • Asymmetric CLASP-Dependent Nucleation of Noncentrosomal Microtubules at the trans-Golgi Network

    Andrey Efimov;Alexey Kharitonov;Nadia Efimova;Jadranka Loncarek

  • C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

    Manal A. Farg;Vinod Sundaramoorthy;Jessica M. Sultana;Shu Yang

  • The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease.

    Alessandra Webers;Alessandra Webers;Michael T Heneka;Michael T Heneka;Paul A Gleeson

  • The Phox Homology (PX) Domain-dependent, 3-Phosphoinositide-mediated Association of Sorting Nexin-1 with an Early Sorting Endosomal Compartment Is Required for Its Ability to Regulate Epidermal Growth Factor Receptor Degradation

    Gyles E. Cozier;Jez Carlton;Alex H. McGregor;Paul A. Gleeson

  • Control of Glycoprotein Synthesis

    P A Gleeson;H Schachter

  • Control of branching during the biosynthesis of asparagine-linked oligosaccharides.

    Harry Schachter;Saroja Narasimhan;Paul Gleeson;George Vella

  • Organ-specific autoimmunity induced by lymphopenia.

    Paul A. Gleeson;Ban‐Hock Toh;Ian R. Van Driel

  • The signal for Golgi retention of bovine beta 1,4-galactosyltransferase is in the transmembrane domain.

    Rohan D. Teasdale;Giacomo Dagostaro;Paul A. Gleeson

  • Intracellular sorting and transport of proteins.

    Catherine Julia van Vliet;Elaine C Thomas;Ana Merino-Trigo;Rohan Teasdale

  • The 60- To 90-kDa Parietal Cell Autoantigen Associated With Autoimmune Gastritis Is a Beta Subunit of the Gastric H+/K(+)-ATPase (Proton Pump)

    B H Toh;P A Gleeson;R J Simpson;R L Moritz

  • A large family of endosome-localized proteins related to sorting nexin 1.

    Rohan D. Teasdale;David Loci;Fiona Houghton;Lars Karlsson

  • AN AUTOIMMUNE-DISEASE WITH MULTIPLE MOLECULAR TARGETS ABROGATED BY THE TRANSGENIC EXPRESSION OF A SINGLE AUTOANTIGEN IN THE THYMUS

    F. Alderuccio;Ban-Hock Toh;Seong-Seng Tan;P. A. Gleeson

  • A novel Golgi-localisation domain shared by a class of coiled-coil peripheral membrane proteins

    Lars Kjer-Nielsen;Rohan D Teasdale;Catherine Julia van Vliet;Paul A Gleeson

  • Visualisation of macropinosome maturation by the recruitment of sorting nexins

    Markus C. Kerr;Margaret R. Lindsay;Robert Luetterforst;Nicholas Hamilton

  • Pollen—stigma interactions: Identification and characterization of surface components with recognition potential

    Adrienne Clarke;Paul Gleeson;Susan Harrison;R. Bruce Knox

  • The trans-Golgi network golgin, GCC185, is required for endosome-to-Golgi transport and maintenance of Golgi structure.

    Merran C. Derby;Zi Zhao Lieu;Darren Brown;Jennifer L. Stow

  • Gastric H+, K+-adenosine triphosphatase β subunit is required for normal function, development, and membrane structure of mouse parietal cells

    Katrina L Scarff;Louise M Judd;Ban-Hock Hock Toh;Paul A Gleeson

  • Targeting of proteins to the Golgi apparatus

    Paul A. Gleeson

Frequent Co-Authors

Ban-Hock Toh
Ban-Hock Toh Monash University
Rohan D. Teasdale
Rohan D. Teasdale University of Queensland
Jennifer L. Stow
Jennifer L. Stow University of Queensland
Adrienne E. Clarke
Adrienne E. Clarke University of Melbourne
Lars Kjer-Nielsen
Lars Kjer-Nielsen University of Melbourne
Harry Schachter
Harry Schachter University of Toronto
Bruno Goud
Bruno Goud Institute Curie
Nicole L. La Gruta
Nicole L. La Gruta Monash University
Seong-Seng Tan
Seong-Seng Tan University of Melbourne
Andrew F. Hill
Andrew F. Hill Victoria University

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