D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 40 Citations 5,103 82 World Ranking 3480 National Ranking 120

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Immune system
  • T cell

Nicole L. La Gruta mainly focuses on T cell, Epitope, Immunology, CD8 and T-cell receptor. Nicole L. La Gruta combines subjects such as Molecular biology and MHC class I, Major histocompatibility complex, Antigen with her study of T cell. Her research investigates the connection between Epitope and topics such as Human leukocyte antigen that intersect with problems in Immune system, Transgene, Autoimmune disease and FOXP3.

Nicole L. La Gruta connects Immunology with Population in her research. As a part of the same scientific study, she usually deals with the CD8, concentrating on Virology and frequently concerns with Immunodominance. Her T-cell receptor study results in a more complete grasp of Genetics.

Her most cited work include:

  • A question of self-preservation: immunopathology in influenza virus infection. (370 citations)
  • Quantifiable predictive features define epitope-specific T cell receptor repertoires (309 citations)
  • Quantifiable predictive features define epitope-specific T cell receptor repertoires (309 citations)

What are the main themes of her work throughout her whole career to date?

T cell, Immunology, CD8, Epitope and T-cell receptor are her primary areas of study. The various areas that she examines in her T cell study include Major histocompatibility complex, Avidity, Antigen, Molecular biology and Cell biology. Her Antigen study combines topics from a wide range of disciplines, such as Cell and Antigen presentation.

Her study in CD8 is interdisciplinary in nature, drawing from both Adoptive cell transfer, Cytokine, Cell growth and Effector. Her research investigates the link between Epitope and topics such as Virology that cross with problems in Immunodominance, Naive T cell and Immunity. As part of the same scientific family, Nicole L. La Gruta usually focuses on T-cell receptor, concentrating on Computational biology and intersecting with Locus and Conserved sequence.

She most often published in these fields:

  • T cell (70.27%)
  • Immunology (64.86%)
  • CD8 (59.46%)

What were the highlights of her more recent work (between 2018-2021)?

  • CD8 (59.46%)
  • T cell (70.27%)
  • Antigen (43.24%)

In recent papers she was focusing on the following fields of study:

Nicole L. La Gruta spends much of her time researching CD8, T cell, Antigen, Epitope and Immunology. Her CD8 research includes themes of Phenotype, Immunity, Neuroscience, Interleukin 15 and Effector. Nicole L. La Gruta interconnects Homeostasis, Cell biology, Influenza A virus, Immunosenescence and MHC class I in the investigation of issues within T cell.

The study incorporates disciplines such as T-cell receptor and Virology in addition to Epitope. Nicole L. La Gruta focuses mostly in the field of Virology, narrowing it down to matters related to Antigen presentation and, in some cases, Immunogenicity and Major histocompatibility complex. Her Immunology research includes elements of Disease and Hospitalized patients.

Between 2018 and 2021, her most popular works were:

  • Most viral peptides displayed by class I MHC on infected cells are immunogenic. (49 citations)
  • Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses. (28 citations)
  • Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses. (28 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • T cell

Nicole L. La Gruta mainly investigates Antigen, Epitope, CD8, Virology and Antigen presentation. Her study in Cell biology extends to Antigen with its themes. Her Epitope research is multidisciplinary, incorporating elements of Immunity and Vaccination.

Her biological study spans a wide range of topics, including Cancer research, Cellular differentiation, Cell growth, T cell and Effector. Her study on Memory T cell is often connected to Recall as part of broader study in T cell. Her Antigen presentation research integrates issues from Antigen-presenting cell, Immunogenicity, MHC class I, Major histocompatibility complex and Naive T cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A question of self-preservation: immunopathology in influenza virus infection.

Nicole L La Gruta;Katherine Kedzierska;John Stambas;Peter C Doherty;Peter C Doherty.
Immunology and Cell Biology (2007)

488 Citations

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

Stephen Scally;Jan Petersen;Soi Cheng Cheng Law;Nadine Lee Dudek.
Journal of Experimental Medicine (2013)

357 Citations

Quantifiable predictive features define epitope-specific T cell receptor repertoires

Pradyot K Dash;Andrew J. Fiore-Gartland;Tomer Hertz;Tomer Hertz;George C. Wang.
Nature (2017)

343 Citations

Hierarchies in Cytokine Expression Profiles for Acute and Resolving Influenza Virus-Specific CD8 + T Cell Responses: Correlation of Cytokine Profile and TCR Avidity

Nicole L. La Gruta;Stephen J. Turner;Peter C. Doherty;Peter C. Doherty.
Journal of Immunology (2004)

243 Citations

A virus-specific CD8 + T cell immunodominance hierarchy determined by antigen dose and precursor frequencies

Nicole L. La Gruta;Katherine Kedzierska;Ken C Pang;Richard Webby.
Proceedings of the National Academy of Sciences of the United States of America (2006)

189 Citations

Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion

Nicole L. La Gruta;William T. Rothwell;Tania Cukalac;Natasha G. Swan.
Journal of Clinical Investigation (2010)

168 Citations

Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations.

Stephen John Turner;Katherine Kedzierska;Helen Komodromou;Nicole Louise La Gruta.
Nature Immunology (2005)

164 Citations

The Majority of Immunogenic Epitopes Generate CD4+ T Cells That Are Dependent on MHC Class II-Bound Peptide-Flanking Residues

Paula Y. Arnold;Nicole L. La Gruta;Tim Miller;Kate M. Vignali.
Journal of Immunology (2002)

137 Citations

Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.

Joshua D Ooi;Jan Petersen;Jan Petersen;Yu H Tan;Megan Huynh.
Nature (2017)

137 Citations

T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease

Jan Petersen;Veronica Montserrat;Jorge R Mujico;Khai Lee Loh.
Nature Structural & Molecular Biology (2014)

136 Citations

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