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Immunology

D-Index
56
Citations
10780
World Ranking
3732
National Ranking
153

Overview

Lorena E. Brown is affiliated with the University of Melbourne in Australia. Their research is primarily situated within the fields of Medicine and Immunology and Microbiology, reflecting a focus on both clinical and molecular aspects of health sciences.

Their scholarly output spans several key subfields, including Epidemiology, Immunology, Infectious Diseases, Molecular Biology, and Agronomy and Crop Science. This multidisciplinary scope supports a comprehensive approach to studying disease mechanisms and immune responses.

Brown's main research topics include:

  • Influenza Virus Research Studies
  • Immune Response and Inflammation
  • Respiratory viral infections research
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction
  • Vaccines and immunoinformatics approaches
  • Interferon and immune responses

Their recent published papers include:

  • Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients, 2021, Nature Communications
  • Selecting and Using the Appropriate Influenza Vaccine for Each Individual, 2021, Viruses
  • TLR2-mediated activation of innate responses in the upper airways confers antiviral protection of the lungs, 2021, JCI Insight
  • Potent priming by inactivated whole influenza virus particle vaccines is linked to viral RNA uptake into antigen presenting cells, 2021, Vaccine
  • Gene Segment Interactions Can Drive the Emergence of Dominant Yet Suboptimal Gene Constellations During Influenza Virus Reassortment, 2021, Frontiers in Microbiology

Brown frequently collaborates with a consistent group of co-authors, which includes:

  • David C. Jackson
  • Katherine Kedzierska
  • Benjamin J. Cowling
  • Hong Kong Senior
  • Rebecca Jane Cox

Their work is regularly published in venues such as Influenza and Other Respiratory Viruses, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Viruses, and JCI Insight. The repeated presence in these journals highlights a focus on respiratory viruses and immune mechanisms.

Best Publications

  • B-1 and B-2 Cell–Derived Immunoglobulin M Antibodies Are Nonredundant Components of the Protective Response to Influenza Virus Infection

    Nicole Baumgarth;Ometa C. Herman;Gina C. Jager;Lorena E. Brown

  • Influenza Virus Neuraminidase Structure and Functions.

    Julie L. McAuley;Brad P. Gilbertson;Sanja Trifkovic;Sanja Trifkovic;Lorena E. Brown

  • Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system

    Nicole Baumgarth;Ometa C. Herman;Gina C. Jager;Lorena Brown

  • Biological activity of monoclonal antibodies to operationally defined antigenic regions on the hemagglutinin molecule of A/Seal/Massachusetts/1 /80 (H7N7) influenza virus

    Hiroshi Kida;Lorena E. Brown;Robert G. Webster

  • A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses

    David C. Jackson;Yuk Fai Lau;Thuy Le;Andreas Suhrbier

  • Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease.

    Julie McAuley;Michelle Tate;Charley Mackenzie-kludas;Anita Pinar

  • Susceptibility of highly pathogenic A(H5N1) avian influenza viruses to the neuraminidase inhibitors and adamantanes.

    Aeron Christopher Giles Hurt;Paul Selleck;Naomi Komadina;Robert P Shaw

  • The structure of the influenza A virus genome.

    Bernadeta Dadonaite;Brad Gilbertson;Michael L Knight;Sanja Trifkovic

  • Influenza A virus facilitates Streptococcus pneumoniae transmission and disease

    Dimitri A Diavatopoulos;Kirsty R Short;John Timothy Price;Jonathan J Wilksch

  • Delivery of Multiple CD8 Cytotoxic T Cell Epitopes by DNA Vaccination

    Scott A. Thomson;Martina A. Sherritt;Jill Medveczky;Suzanne L. Elliott

  • Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines.

    Weiguang Zeng;Souravi Ghosh;Yuk Fai Lau;Lorena E. Brown

  • Antiviral activity of the long chain pentraxin PTX3 against influenza viruses

    Patrick C. Reading;Silvia Bozza;Brad Gilbertson;Michelle Tate

  • The Role of Neutrophils during Mild and Severe Influenza Virus Infections of Mice

    Michelle D. Tate;Lisa J. Ioannidis;Ben Croker;Lorena E. Brown

  • ISCOM-based vaccines: the second decade.

    Megan T Sanders;Lorena E Brown;Georgia Deliyannis;Martin J Pearse

  • Single-cell perforin and granzyme expression reveals the anatomical localization of effector CD8+ T cells in influenza virus-infected mice.

    Barbara J. Johnson;Elaine O. Costelloe;David R. Fitzpatrick;John B. A. G. Haanen

  • Improving the reach of vaccines to low-resource regions, with a needle-free vaccine delivery device and long-term thermostabilization.

    Xianfeng Chen;Germain J.P. Fernando;Michael L. Crichton;Christopher Flaim

  • Potent Immunity to Low Doses of Influenza Vaccine by Probabilistic Guided Micro-Targeted Skin Delivery in a Mouse Model

    Germain J. P. Fernando;Xianfeng Chen;Tarl W. Prow;Michael L. Crichton

  • Location of antigenic sites on the three-dimensional structure of the influenza N2 virus neuraminidase.

    G.M. Air;M.C. Els;L.E. Brown;W.G. Laver

  • The cell surface mucin MUC1 limits the severity of influenza A virus infection.

    J. L. McAuley;L. Corcilius;H. X. Tan;R. J. Payne

  • A fusion DNA vaccine that targets antigen-presenting cells increases protection from viral challenge.

    Georgia Deliyannis;Jefferey S. Boyle;Jamie L. Brady;Lorena E. Brown

Frequent Co-Authors

Katherine Kedzierska
Katherine Kedzierska University of Melbourne
Stephen J. Turner
Stephen J. Turner Monash University
Anne Kelso
Anne Kelso University of Melbourne
Andrew M. Lew
Andrew M. Lew Walter and Eliza Hall Institute of Medical Research
Eric J. Gowans
Eric J. Gowans University of Adelaide
Peter C. Doherty
Peter C. Doherty University of Melbourne
Nicole L. La Gruta
Nicole L. La Gruta Monash University
Patrick C. Reading
Patrick C. Reading University of Melbourne
Joseph Torresi
Joseph Torresi University of Melbourne
Germain J. P. Fernando
Germain J. P. Fernando University of Queensland

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