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Immunology

D-Index
77
Citations
20140
World Ranking
1831
National Ranking
72

Overview

Andrew M. Lew is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, contributing notably to subfields such as Immunology, Surgery, Molecular Biology, Infectious Diseases, and Genetics.

The scientist has published extensively on topics including Immunotherapy and Immune Responses, Immune Cell Function and Interaction, T-cell and B-cell Immunology, Xenotransplantation and immune response, Pancreatic function and diabetes, Immune cells in cancer, and COVID-19 Clinical Research Studies.

Frequent coauthors collaborating with Andrew M. Lew include:

  • Yuxia Zhang
  • Yifan Zhan
  • Zhanghua Chen
  • Fan Bai
  • Jun Cui

Their research has appeared in several key scientific venues, with multiple publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cureus
  • Science Immunology
  • Frontiers in Immunology
  • Transplantation

Among recent papers, some of the noted publications are:

  • Potential therapeutic effects of dipyridamole in the severely ill patients with COVID-19, 2020, Acta Pharmaceutica Sinica B
  • Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity, 2020, Nature Immunology
  • ACE2 expression by colonic epithelial cells is associated with viral infection, immunity and energy metabolism, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia, 2020, Cell
  • IL-17 production by tissue-resident MAIT cells is locally induced in children with pneumonia, 2020, Mucosal Immunology

Their work spans foundational studies and clinical research addressing immune mechanisms and therapeutic approaches, including investigations related to infectious diseases and cancer immunology. The scientist has contributed to understanding immune cell behavior and the development of immunotherapies by exploring T-cell and dendritic cell interactions and immune regulation in disease contexts.

Best Publications

  • Migratory dendritic cells transfer antigen to a lymph node-resident dendritic cell population for efficient CTL priming.

    Rhys S. Allan;Jason Waithman;Sammy Bedoui;Claerwen M. Jones

  • Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells

    Annabell Bachem;Christina Makhlouf;Katrina J. Binger;David P. de Souza

  • The dendritic cell subtype restricted C-type lectin Clec9A is a target for vaccine enhancement

    Irina Caminschi;Anna I Proietto;Fatma Ahmet;Susie Kitsoulis

  • Developmental kinetics, turnover and stimulatory capacity of thymic epithelial cells

    Daniel Herbert Donald Gray;Natalie Louise Seach;Tomoo Ueno;Morag Kertanya Milton

  • The development, maturation, and turnover rate of mouse spleen dendritic cell populations

    Arun T. Kamath;Joanne Pooley;Meredith A. O’Keeffe;David Vremec

  • The need for IgG2c specific antiserum when isotyping antibodies from C57BL/6 and NOD mice

    Roland M. Martin;Jamie L. Brady;Andrew M. Lew

  • Differential development of murine dendritic cells by GM-CSF versus Flt3 ligand has implications for inflammation and trafficking.

    Yuekang Xu;Yuekang Xu;Yifan Zhan;Andrew M. Lew;Shalin H. Naik;Shalin H. Naik

  • CD8 T cell ignorance or tolerance to islet antigens depends on antigen dose

    Christian Kurts;Robyn M. Sutherland;Gayle Davey;Ming Li

  • Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune induction

    Boyle Js;Brady Jl;Lew Am;Lew Am

  • Cell-associated ovalbumin is cross-presented much more efficiently than soluble ovalbumin in vivo.

    Ming Li;Gayle M. Davey;Robyn M. Sutherland;Christian Kurts

  • Integral membrane protein located in the apical complex of Plasmodium falciparum.

    M G Peterson;V M Marshall;J A Smythe;P E Crewther

  • Influence of cellular location of expressed antigen on the efficacy of DNA vaccination: cytotoxic T lymphocyte and antibody responses are suboptimal when antigen is cytoplasmic after intramuscular DNA immunization

    Jefferey S. Boyle;Christina Koniaras;Andrew M. Lew

  • Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1.

    Axel Kallies;Jhagvaral Hasbold;Kirsten Fairfax;Kirsten Fairfax;Clare Pridans;Clare Pridans

  • Innate Immune Surveillance of Spontaneous B Cell Lymphomas by Natural Killer Cells and γδ T Cells

    Shayna E.A. Street;Yoshihiro Hayakawa;Yifan Zhan;Andrew M. Lew

  • Transgenic Expression of Mouse Proinsulin II Prevents Diabetes in Nonobese Diabetic Mice

    Michelle B French;Janette Allison;David S Cram;Helen E Thomas

  • Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways

    Bing Huang;Zhanghua Chen;Lanlan Geng;Jun Wang

  • Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP

    Balasubramanian Krishnamurthy;Nadine L. Dudek;Mark D. McKenzie;Anthony W. Purcell

  • The importance of antibody affinity in the performance of immunoassays for antibody

    Michael W. Steward;Andrew M. Lew

  • Targeting Antigen to Mouse Dendritic Cells via Clec9A Induces Potent CD4 T Cell Responses Biased toward a Follicular Helper Phenotype

    Mireille H. Lahoud;Fatma Ahmet;Susie Kitsoulis;Soo San Wan

  • Potential therapeutic effects of dipyridamole in the severely ill patients with COVID-19.

    Xiaoyan Liu;Zhe Li;Shuai Liu;Jing Sun

  • Characterization of T cell receptor gamma chain expression in a subset of murine thymocytes.

    A. M. Lew;D. M. Pardoll;W. L. Maloy;B. J. Fowlkes

Frequent Co-Authors

Yifan Zhan
Yifan Zhan Walter and Eliza Hall Institute of Medical Research
Peter J. Cowan
Peter J. Cowan University of Melbourne
Leonard C. Harrison
Leonard C. Harrison University of Melbourne
Jose A. Villadangos
Jose A. Villadangos University of Melbourne
Ken Shortman
Ken Shortman Walter and Eliza Hall Institute of Medical Research
William R. Heath
William R. Heath University of Melbourne
Thomas W. H. Kay
Thomas W. H. Kay University of Melbourne
John E. Coligan
John E. Coligan National Institutes of Health
David M. Tarlinton
David M. Tarlinton Monash University
Andreas Strasser
Andreas Strasser Walter and Eliza Hall Institute of Medical Research

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