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Georg A. Holländer

Georg A. Holländer

D-Index & Metrics

Immunology

D-Index
60
Citations
14977
World Ranking
3307
National Ranking
284

Research.com Recognitions

  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Georg A. Holländer is affiliated with the University of Oxford in the United Kingdom. Their research spans multiple aspects of immunology, molecular biology, and medicine, with a particular focus on T-cell and B-cell immunology and immune cell function and interaction.

The recent publications by Georg A. Holländer include:

  • Ageing compromises mouse thymus function and remodels epithelial cell differentiation, 2020, eLife
  • RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy, 2020, Nature
  • High-resolution 3D imaging uncovers organ-specific vascular control of tissue aging, 2021, Science Advances
  • Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases, 2023, Genome Medicine
  • A circulating subset of iNKT cells mediates antitumor and antiviral immunity, 2022, Science Immunology

Frequent co-authors collaborating with Georg A. Holländer include:

  • Stefano Maio
  • Fatima Dhalla
  • Adam E. Handel
  • Mary E. Deadman
  • Saulius Žuklys

The most common publication venues for their work comprise:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Science Advances
  • Science Immunology
  • Frontiers in Immunology

Georg A. Holländer's main fields of study are:

  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, they have focused on subfields including:

  • Immunology
  • Molecular Biology
  • Oncology
  • Endocrinology, Diabetes and Metabolism
  • Genetics

The primary topics of their research work cover:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Single-cell and spatial transcriptomics
  • Immune cells in cancer
  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • RNA Research and Splicing

The scientist is recognized as a Fellow of The Academy of Medical Sciences, United Kingdom.

Best Publications

  • Evolution of the immune system in humans from infancy to old age.

    A K Simon;G A Hollander;A McMichael

  • Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

    Mark A. Daniels;Emma Teixeiro;Jason Gill;Barbara Hausmann

  • Delta-like 4 is indispensable in thymic environment specific for T cell development

    Katsuto Hozumi;Carolina Mailhos;Naoko Negishi;Ken-ichi Hirano

  • β cells are responsible for CXCR3-mediated T-cell infiltration in insulitis

    Simona Frigerio;Tobias Junt;Bao Lu;Craig Gerard

  • Population and single cell genomics reveal the Aire-dependency, relief from Polycomb silencing and distribution of self-antigen expression in thymic epithelia

    Stephen N. Sansom;Noriko Shikama-Dorn;Saule Zhanybekova;Gretel Nusspaumer

  • Normal Thymic Architecture and Negative Selection Are Associated with Aire Expression, the Gene Defective in the Autoimmune-Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED)

    Saulius Zuklys;Gina Balciunaite;Gina Balciunaite;Anni Agarwal;Anni Agarwal;Elizaveta Fasler-Kan

  • Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development

    Yu Lei;Yu Lei;Adiratna Mat Ripen;Naozumi Ishimaru;Izumi Ohigashi

  • Generation of a complete thymic microenvironment by MTS24 + thymic epithelial cells

    Jason Gill;M A Malin;Georg A Hollander;Richard L Boyd

  • Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes

    G. A. Holländer;Baoping Wang;A. Nichogiannopoulou;P. P. Platenburg

  • Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice

    Gina Balciunaite;Marcel P. Keller;Egle Balciunaite;Luca Piali

  • Matrix Metalloproteinase (MMP)-8 and MMP-9 in Cerebrospinal Fluid during Bacterial Meningitis: Association with Blood-Brain Barrier Damage and Neurological Sequelae

    David Leppert;Stephen L. Leib;C. Grygar;K. M. Miller

  • Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen

    Mohammad Alimohammadi;Peyman Björklund;Åsa Hallgren;Nora Pöntynen

  • Autoantigen-specific interactions with CD4(+) thymocytes control mature medullary thymic epithelial cell cellularity

    Magali Irla;Stéphanie Hugues;Jason Gill;Takeshi Nitta

  • Stepwise development of thymic microenvironments in vivo is regulated by thymocyte subsets

    W. van Ewijk;G. Hollander;C. Terhorst;B. Wang

  • Monoallelic Expression of the Interleukin-2 Locus

    Georg A. Holländer;Saulius Zuklys;Corinne Morel;Emiko Mizoguchi

  • Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells.

    Simona W. Rossi;Lukas T. Jeker;Tomoo Ueno;Sachiyo Kuse

  • Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology

    Barbara E. Bierer;Georg Holländer;David Fruman;Steven J. Burakoff

  • Thymic T-cell development in allogeneic stem cell transplantation.

    Werner Krenger;Bruce R. Blazar;Georg A. Holländer;Georg A. Holländer

  • Keratinocyte growth factor preserves normal thymopoiesis and thymic microenvironment during experimental graft-versus-host disease.

    Simona Rossi;Bruce R. Blazar;Catherine L. Farrell;Dimitry M. Danilenko

  • Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging

    Dullei Min;Angela Panoskaltsis-Mortari;Makoto Kuro-o;George A. Hollander

  • Severe colitis in mice with aberrant thymic selection.

    Georg A. Holländer;Stephen J. Simpson;Emiko Mizoguchi;Aliki Nichogiannopoulou

  • The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor

    Aikaterini S Papadopoulou;James Dooley;Michelle A Linterman;Wim Pierson

  • The role of CCL21 in recruitment of T-precursor cells to fetal thymi

    Cunlan Liu;Tomoo Ueno;Sachiyo Kuse;Fumi Saito

Frequent Co-Authors

Bruce R. Blazar
Bruce R. Blazar University of Minnesota
Chris P. Ponting
Chris P. Ponting University of Edinburgh
Steven J. Burakoff
Steven J. Burakoff Icahn School of Medicine at Mount Sinai
Cox Terhorst
Cox Terhorst Beth Israel Deaconess Medical Center
John C. Marioni
John C. Marioni European Bioinformatics Institute
Yousuke Takahama
Yousuke Takahama National Institutes of Health
Emiko Mizoguchi
Emiko Mizoguchi Kurume University
Raif S. Geha
Raif S. Geha Boston Children's Hospital
Hamish S. Scott
Hamish S. Scott University of Adelaide
Richard L. Boyd
Richard L. Boyd Monash University

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