D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 50 Citations 10,097 146 World Ranking 3290 National Ranking 284

Research.com Recognitions

Awards & Achievements

Fellow of The Academy of Medical Sciences, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cytokine

His primary scientific interests are in Immunology, T cell, Cell biology, Stromal cell and Transplantation. His Immunology research incorporates elements of Crosstalk and Adrenal insufficiency. His T cell study integrates concerns from other disciplines, such as Cytotoxic T cell, Cancer research, CD8 and Cellular differentiation.

His Cell biology study incorporates themes from Chemokine, Endocrinology, Internal medicine and T-cell receptor. His Stromal cell research is multidisciplinary, relying on both Keratinocyte growth factor and Autoimmune regulator. His Transplantation study combines topics from a wide range of disciplines, such as FKBP, Stem cell, Pharmacology, Cyclosporin a and Bone marrow.

His most cited work include:

  • Evolution of the immune system in humans from infancy to old age. (602 citations)
  • Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling (463 citations)
  • Delta-like 4 is indispensable in thymic environment specific for T cell development (281 citations)

What are the main themes of his work throughout his whole career to date?

Georg A. Holländer focuses on Cell biology, Immunology, T cell, Transplantation and Immune system. His Cell biology research includes themes of Endocrinology, Cellular differentiation and Stromal cell. His studies in Cellular differentiation integrate themes in fields like Lymphopoiesis, Regulation of gene expression and Signal transduction.

His work deals with themes such as Hematopoietic stem cell transplantation, Stem cell and Haematopoiesis, which intersect with Immunology. The T cell study combines topics in areas such as Cytotoxic T cell, Molecular biology, Cancer research and CD8. His work carried out in the field of Molecular biology brings together such families of science as Receptor and Cell type.

He most often published in these fields:

  • Cell biology (61.32%)
  • Immunology (57.55%)
  • T cell (39.62%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (61.32%)
  • T cell (39.62%)
  • Gene (9.91%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, T cell, Gene, FOXN1 and Thymic involution. His Cell biology research integrates issues from Gene expression and Antigen. His T cell study combines topics in areas such as CD8 and Animal studies.

His study in FOXN1 is interdisciplinary in nature, drawing from both Immunology, Omenn syndrome and Regulatory sequence. His biological study spans a wide range of topics, including Endocrinology and Stromal cell, Internal medicine, Transplantation. His research in Immune system intersects with topics in Hematopoietic stem cell transplantation and Cancer research.

Between 2017 and 2021, his most popular works were:

  • Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells. (19 citations)
  • Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens (14 citations)
  • Ageing compromises mouse thymus function and remodels epithelial cell differentiation (13 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cytokine

Georg A. Holländer mainly focuses on Cell biology, Stem cell, Antigen, Autoimmune regulator and Transcription factor. His studies deal with areas such as FOXN1, Precursor cell, Gene expression and T cell selection as well as Cell biology. The various areas that Georg A. Holländer examines in his Stem cell study include Thymus transplantation, Extracellular matrix, Regeneration and In vivo.

In his study, Medullary cavity is strongly linked to Gene, which falls under the umbrella field of Antigen. His Autoimmune regulator research is multidisciplinary, incorporating elements of Flow cytometry and Interleukin-7 receptor. The subject of his T cell research is within the realm of Immunology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Evolution of the immune system in humans from infancy to old age.

A K Simon;G A Hollander;A McMichael.
Proceedings of The Royal Society B: Biological Sciences (2015)

1266 Citations

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

Mark A. Daniels;Emma Teixeiro;Jason Gill;Barbara Hausmann.
Nature (2006)

593 Citations

Normal Thymic Architecture and Negative Selection Are Associated with Aire Expression, the Gene Defective in the Autoimmune-Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED)

Saulius Zuklys;Gina Balciunaite;Gina Balciunaite;Anni Agarwal;Anni Agarwal;Elizaveta Fasler-Kan.
Journal of Immunology (2000)

369 Citations

Delta-like 4 is indispensable in thymic environment specific for T cell development

Katsuto Hozumi;Carolina Mailhos;Naoko Negishi;Ken-ichi Hirano.
Journal of Experimental Medicine (2008)

366 Citations

β cells are responsible for CXCR3-mediated T-cell infiltration in insulitis

Simona Frigerio;Tobias Junt;Bao Lu;Craig Gerard.
Nature Medicine (2002)

363 Citations

Generation of a complete thymic microenvironment by MTS24 + thymic epithelial cells

Jason Gill;M A Malin;Georg A Hollander;Richard L Boyd.
Nature Immunology (2002)

338 Citations

Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes

G. A. Holländer;Baoping Wang;A. Nichogiannopoulou;P. P. Platenburg.
Nature (1995)

325 Citations

Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice

Gina Balciunaite;Marcel P. Keller;Egle Balciunaite;Luca Piali.
Nature Immunology (2002)

308 Citations

Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development

Yu Lei;Yu Lei;Adiratna Mat Ripen;Naozumi Ishimaru;Izumi Ohigashi.
Journal of Experimental Medicine (2011)

303 Citations

Matrix Metalloproteinase (MMP)-8 and MMP-9 in Cerebrospinal Fluid during Bacterial Meningitis: Association with Blood-Brain Barrier Damage and Neurological Sequelae

David Leppert;Stephen L. Leib;C. Grygar;K. M. Miller.
Clinical Infectious Diseases (2000)

291 Citations

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