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Biology and Biochemistry

D-Index
50
Citations
10273
World Ranking
17550
National Ranking
7204

Overview

Nancy R. Manley is affiliated with the University of Georgia in the United States. Their research primarily spans the fields of Immunology and Microbiology and Medicine, with significant contributions in Immunology, Molecular Biology, Oncology, Endocrine and Autonomic Systems, and Surgery.

Their work covers a range of topics within immunological research, including T-cell and B-cell Immunology, Single-cell and spatial transcriptomics, Immunotherapy and Immune Responses, Immune Cell Function and Interaction, Chemokine receptors and signaling, Circadian rhythm and melatonin, and Renal and related cancers.

Frequent coauthors collaborating with Nancy R. Manley include:

  • Shiyun Xiao
  • Seungwoo Kang
  • Melissa B. Davis
  • Laura P. Hale
  • Brian G. Condie

They have published extensively in several notable venues, with the most frequent publication outlets being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • Development
  • Cancer Research
  • Frontiers in Immunology

Recent publications by Nancy R. Manley include:

  • Age-related epithelial defects limit thymic function and regeneration, 2024, Nature Immunology
  • NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development, 2020, Development
  • Foxn1 overexpression promotes thymic epithelial progenitor cell proliferation and mTEC maintenance, but does not prevent thymic involution, 2023, Development
  • Thymic epithelial cells require lipid kinase Vps34 for CD4 but not CD8 T cell selection, 2022, The Journal of Experimental Medicine
  • Age-related epithelial defects limit thymic function and regeneration, 2021, bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment

    Ute Koch;Emma Fiorini;Rui Benedito;Valerie Besseyrias

  • The role of Hoxa-3 in mouse thymus and thyroid development

    N.R. Manley;M.R. Capecchi

  • Loss of Hox-A1 (Hox-1.6) function results in the reorganization of the murine hindbrain

    Ellen M. Carpenter;Judy M. Goddard;Osamu Chisaka;Nancy R. Manley

  • Mechanisms of thymus organogenesis and morphogenesis

    Julie Gordon;Nancy R. Manley

  • Developing a new paradigm for thymus organogenesis

    C. Clare Blackburn;Nancy R. Manley

  • Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve

    Judy M. Goddard;Mireille Rossel;Nancy R. Manley;Mario R. Capecchi

  • Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands.

    Nancy R. Manley;Mario R. Capecchi

  • An evolutionary perspective on the mechanisms of immunosenescence

    Daryl P. Shanley;Danielle Aw;Nancy R. Manley;Donald B. Palmer

  • Changes in primary lymphoid organs with aging

    Ivan K. Chinn;Clare C. Blackburn;Nancy R. Manley;Gregory D. Sempowski

  • Gcm2 and Foxn1 mark early parathyroid- and thymus-specific domains in the developing third pharyngeal pouch.

    Julie Gordon;Andrea R Bennett;C.Clare Blackburn;Nancy R Manley

  • γ-Secretase inhibitors repress thymocyte development

    Brandon K. Hadland;Nancy R. Manley;Dong Ming Su;Gregory D. Longmore

  • Coordination between CCR7- and CCR9-mediated chemokine signals in prevascular fetal thymus colonization

    Cunlan Liu;Fumi Saito;Zhijie Liu;Yu Lei

  • Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner

    Lizhen Chen;Shiyun Xiao;Nancy R. Manley

  • Functional evidence for a single endodermal origin for the thymic epithelium

    Julie Gordon;Valerie A Wilson;Natalie F Blair;Julie Sheridan

  • An Ancient Gene Network Is Co-Opted for Teeth on Old and New Jaws

    Gareth J Fraser;C. Darrin Hulsey;C. Darrin Hulsey;Ryan F Bloomquist;Kristine Uyesugi

  • Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation

    Nancy R. Manley

  • A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation.

    Dong-ming Su;Samuel Navarre;Won-jong Oh;Brian G Condie

  • Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs.

    Billie A. Moore-Scott;Nancy R. Manley;Nancy R. Manley

  • Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures.

    Nancy R. Manley;Mario R. Capecchi

  • Gene expression pattern Gcm2 and Foxn1 mark early parathyroid- and thymus-specific domains in the developing third pharyngeal pouch

    Julie Gordon;Andrea R. Bennett;C. Clare Blackburn;Nancy R. Manley

Frequent Co-Authors

Mario R. Capecchi
Mario R. Capecchi University of Utah
Marcel R.M. van den Brink
Marcel R.M. van den Brink Memorial Sloan Kettering Cancer Center
Yousuke Takahama
Yousuke Takahama National Institutes of Health
Gregory D. Sempowski
Gregory D. Sempowski Duke University
Lisa A. Newman
Lisa A. Newman Cornell University
James R. Goldenring
James R. Goldenring Vanderbilt University
Julien Sage
Julien Sage Stanford University
Trevor Williams
Trevor Williams Texas A&M University
Shahin Rafii
Shahin Rafii Cornell University
Chris T. Amemiya
Chris T. Amemiya University of California, Merced

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