Mitsuru Matsumoto

Best Publications

• The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance.

  Taishin Akiyama;Yusuke Shimo;Hiromi Yanai;Junwen Qin

  581
  Citations

• The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator

  Yu Hikosaka;Takeshi Nitta;Izumi Ohigashi;Kouta Yano

  490
  Citations

• Role of lymphotoxin and the type I TNF receptor in the formation of germinal centers.

  Mitsuru Matsumoto;Sanjeev Mariathasan;Moon H. Nahm;Ferenc Baranyay

  485
  Citations

• IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9

  Katsuaki Hoshino;Takahiro Sugiyama;Mitsuru Matsumoto;Takashi Tanaka

  453
  Citations

• Development of Autoimmunity against Transcriptionally Unrepressed Target Antigen in the Thymus of Aire-Deficient Mice

  Noriyuki Kuroda;Tasuku Mitani;Naoki Takeda;Naozumi Ishimaru

  353
  Citations

• Dependence of self-tolerance on TRAF6-directed development of thymic stroma

  Taishin Akiyama;Shiori Maeda;Shiori Maeda;Sayaka Yamane;Sayaka Yamane;Kaori Ogino;Kaori Ogino

  340
  Citations

• Abrogation of the alternative complement pathway by targeted deletion of murine factor B

  Mitsuru Matsumoto;Wataru Fukuda;Antonella Circolo;Joseph Goellner

  303
  Citations

• Essential Role of Nuclear Factor (NF)-κB–Inducing Kinase and Inhibitor of κb (Iκb) Kinase α in Nf-κb Activation through Lymphotoxin β Receptor, but Not through Tumor Necrosis Factor Receptor I

  Akemi Matsushima;Tsuneyasu Kaisho;Paul D. Rennert;Hiroyasu Nakano

  299
  Citations

• Lymphotoxin-α (LTα) Supports Development of Splenic Follicular Structure That Is Required for IgG Responses

  Yang Xin Fu;Hector Molina;Mitsuru Matsumoto;Guangming Huang

  290
  Citations

• Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.

  Yoko Hamazaki;Harumi Fujita;Takashi Kobayashi;Yongwon Choi

  287
  Citations

• Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

  Masashi Yano;Noriyuki Kuroda;Hongwei Han;Makiko Meguro-Horike

  285
  Citations

• NF-κB-Inducing Kinase Establishes Self-Tolerance in a Thymic Stroma-Dependent Manner

  Fumiko Kajiura;Shijie Sun;Takashi Nomura;Keisuke Izumi

  269
  Citations

• Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation

  Hiroyasu Nakano;Sachiko Sakon;Haruhiko Koseki;Toshitada Takemori

  264
  Citations

• Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking

  Ryutaro Fukui;Shin-Ichiroh Saitoh;Atsuo Kanno;Masahiro Onji

  255
  Citations

• Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice

  Masashi Nakatani;Yuka Takehara;Hiromu Sugino;Mitsuru Matsumoto

  253
  Citations

• Abnormal Immune Function of Hemopoietic Cells from Alymphoplasia (aly) Mice, a Natural Strain with Mutant NF-κB-Inducing Kinase

  Takuji Yamada;Tasuku Mitani;Kazuko Yorita;Daisuke Uchida

  238
  Citations

• Lymphotoxin‐α‐deficient and TNF receptor‐I‐deficient mice define developmental and functional characteristics of germinal centers

  Mitsuru Matsumoto;Yang Xin Fu;Hector Molina;David D. Chaplin

  222
  Citations

• AIRE Functions As an E3 Ubiquitin Ligase

  Daisuke Uchida;Shigetsugu Hatakeyama;Akemi Matsushima;Hongwei Han

  204
  Citations

• Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.

  Kimi Yamakoshi;Akiko Takahashi;Fumiko Hirota;Rika Nakayama

  204
  Citations

• Npt2a and Npt2c in mice play distinct and synergistic roles in inorganic phosphate metabolism and skeletal development

  Hiroko Segawa;Akemi Onitsuka;Junya Furutani;Ichiro Kaneko

  195
  Citations