World's Best Scientists 2026 revealed!
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Best Female Scientists
2025
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Immunology
USA
2026

D-Index & Metrics

Best Female Scientists

D-Index
158
Citations
86805
World Ranking
105
National Ranking
61

Immunology

D-Index
161
Citations
89220
World Ranking
79
National Ranking
53

Medicine

D-Index
161
Citations
89442
World Ranking
756
National Ranking
429

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2017 - Excellence in Science Award, Federation of American Societies for Experimental Biology (FASEB)
  • 2012 - Fellow of the American Academy of Arts and Sciences
  • 2007 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Microbiology and Immunology
  • 2003 - Member of the National Academy of Sciences
  • 1992 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Diane Mathis is a researcher affiliated with Harvard University in the United States, specializing in immunology and microbiology with a significant focus on medicine. Their body of work spans 109 publications in immunology, with additional contributions in molecular biology, physiology, epidemiology, and rehabilitation.

The main topics of their research include immune cell function and interaction, T-cell and B-cell immunology, IL-33, ST2, and ILC pathways, single-cell and spatial transcriptomics, adipose tissue and metabolism, adipokines, inflammation, and metabolic diseases, as well as exercise and physiological responses.

Mathis has published extensively in prominent scientific journals. Frequent publication venues include:

  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Immunity
  • Science Immunology

Notable recent papers include:

  • The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments, 2021, Nature Communications
  • Tissue regulatory T cells: regulatory chameleons, 2021, Nature Reviews Immunology
  • pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise, 2020, Cell
  • Sex-specific adipose tissue imprinting of regulatory T cells, 2020, Nature
  • Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells, 2022, Cell

The researcher has collaborated frequently with several colleagues, including Christophe Benoıst, Kaitavjeet Chowdhary, Deepshika Ramanan, Daniel A. Michelson, and Silvia Galván-Peña.

Diane Mathis has been recognized with several distinctions throughout their career. These awards include:

  • Excellence in Science Award, Federation of American Societies for Experimental Biology (FASEB), 2017
  • Fellow of the American Academy of Arts and Sciences, 2012
  • Membership in the German National Academy of Sciences Leopoldina, 2007, in the field of Microbiology and Immunology
  • Member of the National Academy of Sciences, 2003
  • Member of Academia Europaea, 1992
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

    Mark S. Anderson;Emily S. Venanzi;Ludger Klein;Zhibin Chen

  • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

    Markus Feuerer;Laura Herrero;Laura Herrero;Daniela Cipolletta;Afia Naaz

  • The Immunological Genome Project: networks of gene expression in immune cells

    Tracy S P Heng;Michio W Painter;Kutlu Elpek;Veronika Lukacs-Kornek

  • Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells

    Hsin Jung Wu;Ivaylo I. Ivanov;Jaime Darce;Jaime Darce;Kimie Hattori;Kimie Hattori

  • FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT

    Yongqing Wu;Madhuri Borde;Vigo Heissmeyer;Markus Feuerer

  • Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota

    Hachung Chung;Hachung Chung;Sünje Johanna Pamp;Sünje Johanna Pamp;Jonathan A. Hill;Neeraj K. Surana;Neeraj K. Surana;Neeraj K. Surana

  • β-Cell death during progression to diabetes

    Diane Mathis;Luis Vence;Christophe Benoist

  • A Special Population of Regulatory T Cells Potentiates Muscle Repair

    Dalia Burzyn;Wilson Kuswanto;Dmitriy Kolodin;Jennifer L. Shadrach;Jennifer L. Shadrach

  • PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue T reg cells

    Daniela Cipolletta;Markus Feuerer;Markus Feuerer;Amy Li;Nozomu Kamei;Nozomu Kamei

  • Organ-Specific Disease Provoked by Systemic Autoimmunity

    Valérie Kouskoff;Anne-Sophie Korganow;Véronique Duchatelle;Claude Degott

  • Mice lacking MHC class II molecules

    Dominic Cosgrove;David Gray;Andrée Dierich;Jim Kaufman

  • The AKT–mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells

    Sokol Haxhinasto;Diane Mathis;Diane Mathis;Christophe Benoist;Christophe Benoist

  • Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses.

    Nicole Joller;Ester Lozano;Patrick R. Burkett;Bonny Patel

  • From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins

    Anne-Sophie Korganow;Hong Ji;Sara Mangialaio;Véronique Duchatelle

  • Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch

    Paul Cohen;Julia D. Levy;Yingying Zhang;Andrea Frontini

  • A multiplicity of CCAAT box-binding proteins

    Arnulf Dorn;Jacques Bollekens;Adrian Staub;Christophe Benoist

  • Mast Cells: A Cellular Link Between Autoantibodies and Inflammatory Arthritis

    David M. Lee;Daniel S. Friend;Michael F. Gurish;Christophe Benoist

  • Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis.

    Xinyang Song;Ximei Sun;Sungwhan F. Oh;Sungwhan F. Oh;Meng Wu

  • Individual intestinal symbionts induce a distinct population of RORγ+ regulatory T cells

    Esen Sefik;Naama Geva-Zatorsky;Sungwhan Oh;Liza Konnikova

  • Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme.

    Isao Matsumoto;Adrien Staub;Christophe Benoist;Diane Mathis

  • Following a diabetogenic T cell from genesis through pathogenesis.

    Jonathan D. Katz;Bo Wang;Kathryn Haskins;Christophe Benoist

Frequent Co-Authors

Christophe Benoist
Christophe Benoist Harvard University
Ralph Weissleder
Ralph Weissleder Harvard University
Aviv Regev
Aviv Regev Genentech
Amy J. Wagers
Amy J. Wagers Harvard University
Antonio Gonzalez
Antonio Gonzalez University of Santiago de Compostela
Valerie Kouskoff
Valerie Kouskoff University of Manchester
Dennis L. Kasper
Dennis L. Kasper Harvard University
Daphne Koller
Daphne Koller insitro Inc.
Andrée Dierich
Andrée Dierich Institute of Genetics and Molecular and Cellular Biology
Philip L. De Jager
Philip L. De Jager Columbia University

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