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Immunology

D-Index
105
Citations
57147
World Ranking
576
National Ranking
344

Overview

Dario A. A. Vignali is affiliated with the University of Pittsburgh in the United States and conducts research primarily in the fields of Medicine, Immunology, and Microbiology. Their scholarly work spans multiple subfields including Immunology, Oncology, Molecular Biology, Neurology, and Pulmonary and Respiratory Medicine.

Their research focuses on key topics such as Cancer Immunotherapy and Biomarkers, Immune Cell Function and Interaction, T-cell and B-cell Immunology, CAR-T cell therapy research, Immunotherapy and Immune Responses, Immune cells in cancer, and Gut microbiota and health.

Among recent publications, Vignali is associated with the following papers:

  • Metabolic support of tumour-infiltrating regulatory T cells by lactic acid (2021, Nature)
  • Immune Landscape of Viral- and Carcinogen-Driven Head and Neck Cancer (2020, Immunity)
  • Interferon-γ: teammate or opponent in the tumour microenvironment? (2021, Nature Reviews Immunology)
  • Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment (2023, Cell)
  • B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma (2021, Nature Communications)

Vignali collaborates frequently with several co-authors, including:

  • Creg J. Workman
  • Tullia C. Bruno
  • Anthony R. Cillo
  • Robert L. Ferris
  • Sayali Onkar

Their work has been published extensively in venues such as:

  • The Journal of Immunology
  • Regular and Young Investigator Award Abstracts
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Clinical Cancer Research

Best Publications

  • How regulatory T cells work.

    Dario A. A. Vignali;Lauren W. Collison;Creg J. Workman

  • The inhibitory cytokine IL-35 contributes to regulatory T-cell function

    Lauren W. Collison;Creg J. Workman;Timothy T. Kuo;Kelli Boyd

  • Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

    Shawn D Blackburn;Haina Shin;W Nicholas Haining;W Nicholas Haining;Tao Zou

  • Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape

    Seng Ryong Woo;Meghan E Turnis;Monica V Goldberg;Jaishree Bankoti

  • Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene.

    Kazuya Shimoda;Jan van Deursent;Mark Y. Sangster;Sally R. Sarawar

  • Role of LAG-3 in regulatory T cells.

    Ching Tai Huang;Creg J. Workman;Dallas Flies;Xiaoyu Pan

  • Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

    W. E. Thierfelder;J. M. Van Deursen;K. Yamamoto;R. A. Tripp

  • Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector.

    Andrea L Szymczak;Andrea L Szymczak;Creg J Workman;Yao Wang;Kate M Vignali

  • IL-12 family cytokines: immunological playmakers

    Dario A A Vignali;Vijay K Kuchroo

  • Multiplexed particle-based flow cytometric assays.

    Dario A.A. Vignali

  • Metabolic support of tumour-infiltrating regulatory T cells by lactic acid.

    McLane L.J. Watson;Paolo D.A. Vignali;Steven J. Mullett;Abigail E. Overacre-Delgoffe;Abigail E. Overacre-Delgoffe

  • Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

    R. M. Chicz;R. G. Urban;J. C. Gorga;D. A. A. Vignali

  • IL-35-mediated induction of a potent regulatory T cell population

    Lauren W Collison;Vandana Chaturvedi;Abigail L Henderson;Abigail L Henderson;Paul R Giacomin

  • LAG3 (CD223) as a cancer immunotherapy target.

    Lawrence P. Andrews;Ariel E. Marciscano;Charles G. Drake;Dario A. A. Vignali

  • Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

    Roman M. Chicz;Robert G. Urban;William S. Lane;Joan C. Gorga;Joan C. Gorga

  • Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3

    Jun Wang;Miguel F. Sanmamed;Ila Datar;Tina Tianjiao Su

  • Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3

    Xiaobo Mao;Michael Tianhao Ou;Senthilkumar S. Karuppagounder;Tae In Kam

  • Regulatory T Cells Inhibit Dendritic Cells by Lymphocyte Activation Gene-3 Engagement of MHC Class II

    Bitao Liang;Craig Workman;Janine Lee;Claude Chew

  • Regulatory T cells: recommendations to simplify the nomenclature

    Abul K Abbas;Christophe Benoist;Jeffrey A Bluestone;Daniel J Campbell

  • Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling

    Sivakumar Vallabhapurapu;Atsushi Matsuzawa;Wei Zhou Zhang;Ping Hui Tseng

  • Stability and function of regulatory T cells is maintained by a neuropilin-1–semaphorin-4a axis

    Greg M. Delgoffe;Seng-Ryong Woo;Meghan E. Turnis;David M. Gravano

Frequent Co-Authors

Creg J. Workman
Creg J. Workman University of Pittsburgh
Tullia C. Bruno
Tullia C. Bruno University of Pittsburgh
Robert L. Ferris
Robert L. Ferris University of Pittsburgh
Jonathan D. Powell
Jonathan D. Powell Johns Hopkins University School of Medicine
Charles G. Drake
Charles G. Drake Columbia University
Jack L. Strominger
Jack L. Strominger Harvard University
Arlene H. Sharpe
Arlene H. Sharpe Harvard University
Bruce R. Blazar
Bruce R. Blazar University of Minnesota
David L. Woodland
David L. Woodland Trudeau Institute
Robert Lafyatis
Robert Lafyatis University of Pittsburgh

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