Robert Lafyatis

Overview

Best Publications

• SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.

  Carly G.K. Ziegler;Samuel J. Allon;Sarah K. Nyquist;Ian M. Mbano

  2401
  Citations

• Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex.

  Seong Jin Kim;Peter Angel;Robert Lafyatis;Kazue Hattori

  951
  Citations

• Proliferating SPP1/MERTK-expressing Macrophages in Idiopathic Pulmonary Fibrosis

  Christina Morse;Tracy Tabib;John Sembrat;Kristina L. Buschur

  760
  Citations

• Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial

  Dinesh Khanna;Christopher P Denton;Angelika Jahreis;Jacob M van Laar

  708
  Citations

• Immune Landscape of Viral- and Carcinogen-Driven Head and Neck Cancer

  Anthony R. Cillo;Cornelius H.L. Kürten;Cornelius H.L. Kürten;Tracy Tabib;Zengbiao Qi

  643
  Citations

• Adaptive plasticity of IL-10 + and IL-35 + T reg cells cooperatively promotes tumor T cell exhaustion

  Deepali V Sawant;Deepali V Sawant;Hiroshi Yano;Maria Chikina;Qianxia Zhang;Qianxia Zhang

  517
  Citations

• Proteome-wide Analysis and CXCL4 as a Biomarker in Systemic Sclerosis

  L. Van Bon;L. Van Bon;A. J. Affandi;A. J. Affandi;J. Broen;J. Broen;R. B. Christmann

  498
  Citations

• Generation of Transgene‐Free Lung Disease‐Specific Human Induced Pluripotent Stem Cells Using a Single Excisable Lentiviral Stem Cell Cassette

  Aba Somers;Jyh‐Chang Jean;Cesar A. Sommer;Amel Omari

  493
  Citations

• Anchorage-independent growth of synoviocytes from arthritic and normal joints. Stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-beta and retinoids.

  R Lafyatis;E F Remmers;A B Roberts;D E Yocum

  466
  Citations

• Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

  Gerald S. Horan;Susan Wood;Victor Ona;Dan Jun Li

  453
  Citations

• Localization and actions of transforming growth factor-beta s in the embryonic nervous system.

  K.C. Flanders;G. Ludecke;S. Engels;D.S. Cissel

  452
  Citations

• Shared and distinct mechanisms of fibrosis

  Jörg H. W. Distler;Andrea-Hermina Györfi;Meera Ramanujam;Michael L. Whitfield

  444
  Citations

• Transforming growth factor beta isoforms in the adult rat central and peripheral nervous system

  K. Unsicker;K.C. Flanders;D.S. Cissel;R. Lafyatis

  431
  Citations

• A macrophage marker, Siglec-1, is increased on circulating monocytes in patients with systemic sclerosis and induced by type I interferons and toll-like receptor agonists.

  Michael R. York;Taro Nagai;Alyson J. Mangini;Raphaël Lemaire

  400
  Citations

• Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.

  Joana P. Bernardes;Neha Mishra;Florian Tran;Thomas Bahmer

  377
  Citations

• Transforming growth factor β—at the centre of systemic sclerosis

  Robert Lafyatis

  359
  Citations

• Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients

  Lisa M. Rice;Cristina M. Padilla;Sarah R. McLaughlin;Allison Mathes

  351
  Citations

• B cell depletion with rituximab in patients with diffuse cutaneous systemic sclerosis

  Robert Lafyatis;Eugene Kissin;Michael York;Giuseppina Farina

  326
  Citations

• Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma.

  Swati Bhattacharyya;Kathleen Kelley;Denisa S. Melichian;Zenshiro Tamaki

  307
  Citations

• SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin.

  Tracy Tabib;Christina Morse;Ting Wang;Wei Chen

  296
  Citations