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Nicola C. Partridge

Nicola C. Partridge

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
14553
World Ranking
8293
National Ranking
3749

Research.com Recognitions

  • 2019 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Nicola C. Partridge is affiliated with New York University in the United States and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work encompasses significant contributions to subfields such as Molecular Biology, Oncology, Cancer Research, Endocrinology, Diabetes and Metabolism, and Genetics.

The scientist's main research topics include Bone health and treatments, Bone Metabolism and Diseases, TGF-β signaling in diseases, MicroRNA in disease regulation, Growth Hormone and Insulin-like Growth Factors, Metabolism, Diabetes, and Cancer, and Parathyroid Disorders and Treatments.

Nicola C. Partridge has multiple frequent co-authors, including Zhiming He, Carole Le Hénaff, N. Selvamurugan, Michael J Mosca, and M. Rohini, illustrating a collaborative research environment.

Their publications appear extensively in venues such as the Journal of the Endocrine Society, FASEB BioAdvances, UNC Libraries, Journal of Cellular Physiology, and Bone.

Recent papers by Partridge include

  • miR-873-3p targets HDAC4 to stimulate matrix metalloproteinase-13 expression upon parathyroid hormone exposure in rat osteoblasts (2020, Journal of Cellular Physiology)
  • Osteoblastic monocyte chemoattractant protein-1 (MCP-1) mediation of parathyroid hormone's anabolic actions in bone implicates TGF-β signaling (2020, Bone)
  • MiR-4638-3p regulates transforming growth factor-β1-induced activating transcription factor-3 and cell proliferation, invasion, and apoptosis in human breast cancer cells (2022, International Journal of Biological Macromolecules)
  • Regulation of transforming growth factor-β1-stimulation of Runx2 acetylation for matrix metalloproteinase 13 expression in osteoblastic cells (2021, Biological Chemistry)
  • The Critical Role of MMP13 in Regulating Tooth Development and Reactionary Dentinogenesis Repair Through the Wnt Signaling Pathway (2022, Frontiers in Cell and Developmental Biology)

The scope of these publications reflects investigations into molecular mechanisms of bone metabolism, gene regulation, and cancer cell behavior.

Nicola C. Partridge is a Fellow of the American Association for the Advancement of Science (AAAS), having received this recognition in 2019.

Best Publications

  • Cellular and Molecular Mechanisms of Bone Remodeling

    Liza Jane Raggatt;Nicola C. Partridge

  • Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement

    Jawed A. Siddiqui;Nicola C. Partridge

  • Parathyroid hormone-dependent signaling pathways regulating genes in bone cells

    John T. Swarthout;Richard C. D'Alonzo;Nagarajan Selvamurugan;Nicola C. Partridge

  • Parathyroid hormone: a double-edged sword for bone metabolism

    Ling Qin;Liza J. Raggatt;Nicola C. Partridge

  • Morphological and Biochemical Characterization of Four Clonal Osteogenic Sarcoma Cell Lines of Rat Origin

    N C Partridge;D Alcorn;V P Michelangeli;G Ryan

  • Functional properties of hormonally responsive cultured normal and malignant rat osteoblastic cells.

    N.C. Partridge;D. Alcorn;V.P. Michelangeli;B.E. Kemp

  • The Physician-Scientist: Career Issues and Challenges at the Year 2000

    Tamara R. Zemlo;Howard H. Garrison;Nicola C. Partridge;Timothy J. Ley

  • Rat collagenase. Cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells.

    C O Quinn;D K Scott;C E Brinckerhoff;L M Matrisian

  • Parathyroid Hormone Stimulates Osteoblastic Expression of MCP-1 to Recruit and Increase the Fusion of Pre/Osteoclasts *

    Xin Li;Ling Qin;Marika Bergenstock;Laura M. Bevelock

  • Glucocorticoids promote development of the osteoblast phenotype by selectively modulating expression of cell growth and differentiation associated genes.

    Victoria Shalhoub;Donna Conlon;Melissa S. Tassinari;Cheryl Quinn

  • Parathyroid Hormone Regulation of the Rat Collagenase-3 Promoter by Protein Kinase A-dependent Transactivation of Core Binding Factor α1 *

    Nagarajan Selvamurugan;Malini R. Pulumati;Darren R. Tyson;Nicola C. Partridge

  • Histologic observation of a human immature permanent tooth with irreversible pulpitis after revascularization/regeneration procedure.

    Emi Shimizu;George Jong;Nicola Partridge;Paul A. Rosenberg

  • Isolation and characterization of a novel coactivator protein, NCoA-62, involved in vitamin D-mediated transcription.

    Troy A. Baudino;Dennis M. Kraichely;Stephen C. Jefcoat;Sandra K. Winchester

  • Activation of adenosine 3',5'-monophosphate-dependent protein kinase in normal and malignant bone cells by parathyroid hormone, prostaglandin E2, and prostacyclin

    Nicola Partridge;B. E. Kemp;M. C. Veroni;T. J. Martin

  • Characterization of an osteoblast-like clonal cell line which responds to both parathyroid hormone and calcitonin.

    S. M. Forrest;K. W. Ng;D. M. Findlay;V. P. Michelangeli

  • Gene expression profiles and transcription factors involved in parathyroid hormone signaling in osteoblasts revealed by microarray and bioinformatics

    Ling Qin;Ping Qiu;Luquan Wang;Xin Li

  • Hormonal regulation of the production of collagenase and a collagenase inhibitor activity by rat osteogenic sarcoma cells

    N. C. Partridge;J. J. Jeffrey;J. J. Jeffrey;L. S. Ehlich;L. S. Ehlich;S. L. Teitelbaum;S. L. Teitelbaum

  • Regulation of plasminogen activator production by bone-resorbing hormones in normal and malignant osteoblasts.

    J. A. Hamilton;S. Lingelbach;N. C. Partridge;T. J. Martin

  • Bio-composite scaffolds containing chitosan/nano-hydroxyapatite/nano-copper-zinc for bone tissue engineering.

    Anjali Tripathi;Sekaran Saravanan;Soumitri Pattnaik;Ambigapathi Moorthi

  • Determination of Dual Effects of Parathyroid Hormone on Skeletal Gene Expression in Vivo by Microarray and Network Analysis

    Xin Li;Hao Liu;Ling Qin;Joseph Tamasi

Frequent Co-Authors

John J. Jeffrey
John J. Jeffrey Albany Medical Center Hospital
Steven L. Teitelbaum
Steven L. Teitelbaum Washington University in St. Louis
David M. Findlay
David M. Findlay University of Adelaide
John A. Eisman
John A. Eisman Garvan Institute of Medical Research
Keith A. Hruska
Keith A. Hruska Washington University in St. Louis
John A. Hamilton
John A. Hamilton University of Melbourne
Bruce E. Kemp
Bruce E. Kemp Australian Catholic University
Stephen M. Krane
Stephen M. Krane Harvard University
Daniel B. Rifkin
Daniel B. Rifkin New York University
Emanuel DiCicco-Bloom
Emanuel DiCicco-Bloom Rutgers, The State University of New Jersey

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