M. Neale Weitzmann spends much of his time researching Endocrinology, Internal medicine, Bone resorption, Osteoclast and Bone remodeling. M. Neale Weitzmann is involved in the study of Endocrinology that focuses on Osteoporosis in particular. His work carried out in the field of Osteoporosis brings together such families of science as Acquired immune system, Inflammation, Immunology, Immune system and Estrogen.
His biological study spans a wide range of topics, including Osteoprotegerin, Osteoblast and Cell biology. M. Neale Weitzmann combines subjects such as RANKL and RANK Ligand with his study of Osteoclast. His research in Bone remodeling tackles topics such as Bone density which are related to areas like Bone mineral.
His primary scientific interests are in Internal medicine, Endocrinology, Bone resorption, Bone remodeling and Osteoporosis. His Internal medicine study combines topics in areas such as Wnt signaling pathway, CD40 and Cell biology. His Endocrinology research includes themes of Cytokine, T cell, Osteoblast, Parathyroid hormone and Bone marrow.
M. Neale Weitzmann combines subjects such as Osteoclast, Peak bone mass, Osteopenia and RANKL with his study of Bone resorption. His research in Bone remodeling intersects with topics in Immune system, Metabolomics, Bone mineral, Bone density and Senile osteoporosis. M. Neale Weitzmann works mostly in the field of Osteoporosis, limiting it down to topics relating to Immunology and, in certain cases, Bone disease and Oncology.
The scientist’s investigation covers issues in Internal medicine, Endocrinology, Bone resorption, Osteoporosis and Bone remodeling. His study in Internal medicine is interdisciplinary in nature, drawing from both Protein kinase B and Oncology. His Endocrinology research is multidisciplinary, incorporating perspectives in T cell, Osteoclast, CD8, Parathyroid hormone and Bone marrow.
His studies deal with areas such as Tumor necrosis factor alpha, Osteoblast and Cell biology as well as T cell. His biological study spans a wide range of topics, including Cortical bone, Immunology and RANKL. His research integrates issues of Bone mineral and Metabolomics in his study of Bone remodeling.
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Estrogen deficiency and bone loss: an inflammatory tale
M. Neale Weitzmann;Roberto Pacifici.
Journal of Clinical Investigation (2006)
IFN-γ stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation
Yuhao Gao;Francesco Grassi;Michaela Robbie Ryan;Masakazu Terauchi.
Journal of Clinical Investigation (2007)
B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo.
Yan Li;Gianluca Toraldo;Aimin Li;Xiaoying Yang.
Blood (2007)
Estrogen Decreases Osteoclast Formation by Down-regulating Receptor Activator of NF-κB Ligand (RANKL)-induced JNK Activation
Sunil Srivastava;Gianluca Toraldo;M. Neale Weitzmann;Simone Cenci.
Journal of Biological Chemistry (2001)
Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-γ-induced class II transactivator
Simone Cenci;Gianluca Toraldo;M. Neale Weitzmann;Cristiana Roggia.
Proceedings of the National Academy of Sciences of the United States of America (2003)
IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor κB ligand and tumor necrosis factor α from T cells
Gianluca Toraldo;Cristiana Roggia;Wei-Ping Qian;Roberto Pacifici.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics
Jau-Yi Li;Benoit Chassaing;Abdul Malik Tyagi;Chiara Vaccaro.
Journal of Clinical Investigation (2016)
The role of T lymphocytes in bone metabolism.
M. Neale Weitzmann;Roberto Pacifici.
Immunological Reviews (2005)
Endogenous TNFα Lowers Maximum Peak Bone Mass and Inhibits Osteoblastic Smad Activation Through NF‐κB
Yan Li;Aimin Li;Karen Strait;Hongying Zhang.
Journal of Bone and Mineral Research (2007)
T Lymphocytes Amplify the Anabolic Activity of Parathyroid Hormone Through Wnt10b Signaling
Masakazu Terauchi;Jau-Yi Li;Brahmchetna Bedi;Ki-Hyun Baek.
Cell Metabolism (2009)
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