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M. Neale Weitzmann

M. Neale Weitzmann

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
15081
World Ranking
12392
National Ranking
5308

Overview

M. Neale Weitzmann is affiliated with Emory University in the United States. Their research spans multiple fields, with a prominent focus on medicine and biochemistry, genetics, and molecular biology. Subfields in which they have contributed include molecular biology, genetics, immunology, orthopedics and sports medicine, as well as emergency medicine.

The scientist's work involves key topics such as HIV-related health complications and treatments, bone and joint diseases, vitamin D research studies, bone health and osteoporosis research, bone metabolism and diseases, metabolism and genetic disorders, and broader HIV research and treatment.

Recent publications by Weitzmann highlight a focus on bone biology and microbiome interactions. These include:

  • Parathyroid hormone-dependent bone formation requires butyrate production by intestinal microbiota, 2020, Journal of Clinical Investigation
  • PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells, 2020, Nature Communications
  • Ovariectomy induces bone loss via microbial-dependent trafficking of intestinal TNF+ T cells and Th17 cells, 2021, Journal of Clinical Investigation
  • Metabolomic Associations with Serum Bone Turnover Markers, 2020, Nutrients
  • The microbiome restrains melanoma bone growth by promoting intestinal NK and Th1 cell homing to bone, 2022, Journal of Clinical Investigation

The scientist frequently publishes in certain academic journals, notably:

  • Journal of Clinical Investigation (5 publications)
  • The Journal of Infectious Diseases (3 publications)
  • Current Developments in Nutrition (3 publications)
  • eLife (2 publications)
  • AIDS (2 publications)

Weitzmann collaborates regularly with several researchers, including Roberto Pacifici, Daiana Weiss, Ighovwerha Ofotokun, Subhashis Pal, and Thomas R. Ziegler, with co-authorship counts ranging from six to eleven papers with each.

Best Publications

  • Estrogen deficiency and bone loss: an inflammatory tale

    M. Neale Weitzmann;Roberto Pacifici

  • Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics

    Jau-Yi Li;Benoit Chassaing;Abdul Malik Tyagi;Chiara Vaccaro

  • B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo.

    Yan Li;Gianluca Toraldo;Aimin Li;Xiaoying Yang

  • IFN-γ stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation

    Yuhao Gao;Francesco Grassi;Michaela Robbie Ryan;Masakazu Terauchi

  • Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-kappa B ligand (RANKL)-induced JNK activation.

    Sunil Srivastava;Gianluca Toraldo;M. Neale Weitzmann;Simone Cenci

  • The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression.

    Abdul Malik Tyagi;Mingcan Yu;Trevor M. Darby;Chiara Vaccaro

  • Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-γ-induced class II transactivator

    Simone Cenci;Gianluca Toraldo;M. Neale Weitzmann;Cristiana Roggia

  • IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor κB ligand and tumor necrosis factor α from T cells

    Gianluca Toraldo;Cristiana Roggia;Wei-Ping Qian;Roberto Pacifici

  • Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD

    Sunil Srivastava;M. Neale Weitzmann;Simone Cenci;F. Patrick Ross

  • The Role of Inflammatory Cytokines, the RANKL/OPG Axis, and the Immunoskeletal Interface in Physiological Bone Turnover and Osteoporosis

    M. Neale Weitzmann;M. Neale Weitzmann

  • The role of T lymphocytes in bone metabolism.

    M. Neale Weitzmann;Roberto Pacifici

  • Endogenous TNFα Lowers Maximum Peak Bone Mass and Inhibits Osteoblastic Smad Activation Through NF‐κB

    Yan Li;Aimin Li;Karen Strait;Hongying Zhang

  • Bioactive silica-based nanoparticles stimulate bone-forming osteoblasts, suppress bone-resorbing osteoclasts, and enhance bone mineral density in vivo.

    George R. Beck;Shin-Woo Ha;Corinne E. Camalier;Masayoshi Yamaguchi

  • T Lymphocytes Amplify the Anabolic Activity of Parathyroid Hormone Through Wnt10b Signaling

    Masakazu Terauchi;Jau-Yi Li;Brahmchetna Bedi;Ki-Hyun Baek

  • Zinc stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-κB activation.

    Masayoshi Yamaguchi;M. Neale Weitzmann;M. Neale Weitzmann

  • Physiological and pathophysiological bone turnover - role of the immune system.

    M. Neale Weitzmann;M. Neale Weitzmann;Ighovwerha Ofotokun

  • Estrogen prevents bone loss through transforming growth factor β signaling in T cells

    Yuhao Gao;Wei-Ping Qian;Kimberly Dark;Gianluca Toraldo

  • Bioactive silica nanoparticles promote osteoblast differentiation through stimulation of autophagy and direct association with LC3 and p62.

    Shin-Woo Ha;M. Neale Weitzmann;M. Neale Weitzmann;George R. Beck;George R. Beck

  • Ovariectomy disregulates osteoblast and osteoclast formation through the T-cell receptor CD40 ligand.

    Jau-Yi Li;Hesham Tawfeek;Brahmchetna Bedi;Xiaoying Yang

  • Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation

    Francesco Grassi;Gianluca Tell;Michaela Robbie-Ryan;Yuhao Gao

Frequent Co-Authors

Jeffrey L. Lennox
Jeffrey L. Lennox Emory University
Leland W.K. Chung
Leland W.K. Chung Cedars-Sinai Medical Center
Dean P. Jones
Dean P. Jones Emory University
Haiyen E. Zhau
Haiyen E. Zhau Cedars-Sinai Medical Center
Thomas R. Ziegler
Thomas R. Ziegler Emory University
Hicham Drissi
Hicham Drissi Emory University
Henry M. Kronenberg
Henry M. Kronenberg Harvard University
Masayoshi Yamaguchi
Masayoshi Yamaguchi University of Hawaii at Manoa
Kirk A. Easley
Kirk A. Easley Emory University
Joseph J. Eron
Joseph J. Eron University of North Carolina at Chapel Hill

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