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Biology and Biochemistry

D-Index
52
Citations
9534
World Ranking
16705
National Ranking
6902

Overview

Laura R. McCabe is affiliated with Michigan State University in the United States, with a research focus spanning Medicine and Biochemistry, Genetics and Molecular Biology. Their work covers multiple subfields including Molecular Biology, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Physiology, and Surgery.

Their research mainly addresses key scientific topics such as gut microbiota and health, diet and metabolism studies, microscopic colitis, drug transport and resistance mechanisms, peroxisome proliferator-activated receptors, metabolism and genetic disorders, and vitamin D research studies.

Frequent publication venues for their work include Bone, Journal of Lipid Research, Frontiers in Immunology, JBMR Plus, and Frontiers in Pharmacology.

Notable recent publications by McCabe include:

  • Post-antibiotic gut dysbiosis-induced trabecular bone loss is dependent on lymphocytes, 2020, Bone
  • Baat Gene Knockout Alters Post-Natal Development, the Gut Microbiome, and Reveals Unusual Bile Acids in Mice, 2022, Journal of Lipid Research
  • Use of Thyroid Hormones in Hypothyroid and Euthyroid Patients: A THESIS questionnaire survey of members of the Irish Endocrine Society, 2022, Irish Journal of Medical Science (1971 -)
  • Comparative effects of human-equivalent low, moderate, and high dose oral prednisone intake on autoimmunity and glucocorticoid-related toxicity in a murine model of environmental-triggered lupus, 2022, Frontiers in Immunology
  • Lactobacillus Reuteri 6475 Prevents Bone Loss in a Clinically Relevant Oral Model of Glucocorticoid-Induced Osteoporosis in Male CD -1 Mice, 2023, JBMR Plus

Frequent co-authors include:

  • Narayanan Parameswaran
  • Nicholas J. Chargo
  • Robert A. Quinn
  • Kerri A. Neugebauer
  • Douglas V. Guzior

Best Publications

  • Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging

    Yun Hee Youm;Ryan W. Grant;Laura R. McCabe;Diana C. Albarado

  • Runt Homology Domain Proteins in Osteoblast Differentiation: AML3/CBFA1 Is a Major Component of a Bone-Specific Complex

    Chaitali Banerjee;Laura R. McCabe;Je-Yong Choi;Scott W. Hiebert

  • Probiotic L. reuteri treatment prevents bone loss in a menopausal ovariectomized mouse model.

    Robert A. Britton;Regina Irwin;Darin Quach;Laura Schaefer

  • Probiotic use decreases intestinal inflammation and increases bone density in healthy male but not female mice

    Laura R. McCabe;Regina Irwin;Laura Schaefer;Robert A. Britton

  • Chronic hyperglycemia modulates osteoblast gene expression through osmotic and non-osmotic pathways.

    Sergiu Botolin;Laura R. McCabe

  • Increased Bone Adiposity and Peroxisomal Proliferator-Activated Receptor-γ2 Expression in Type I Diabetic Mice

    Sergiu Botolin;Marie Claude Faugere;Hartmut Malluche;Michael Orth

  • Understanding the Pathology and Mechanisms of Type I Diabetic Bone Loss

    Laura R. McCabe

  • Prebiotic and Probiotic Regulation of Bone Health: Role of the Intestine and its Microbiome.

    Laura McCabe;Robert A. Britton;Narayanan Parameswaran

  • Developmental Expression and Activities of Specific Fos and Jun Proteins Are Functionally Related to Osteoblast Maturation: Role of Fra-2 and Jun D during Differentiation*

    Laura R. McCabe;Chaitali Banerjee;R. Kundu;Robert J. Harrison

  • Hydroxyapatite accelerates differentiation and suppresses growth of MC3T3‐E1 osteoblasts

    R. Shu;R. McMullen;M. J. Baumann;L. R. McCabe

  • TGF beta alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype.

    Ellen C. Breen;Ronald A. Ignotz;Laura R. McCabe;Janet L. Stein

  • Osteoblasts respond to hydroxyapatite surfaces with immediate changes in gene expression.

    Jianwei Xie;Melissa J. Baumann;Laura R. McCabe

  • Selective expression of fos- and jun-related genes during osteoblast proliferation and differentiation.

    Laura R. McCabe;Maaike Kockx;Jane Lian;Janet Stein

  • The Potential of Probiotics as a Therapy for Osteoporosis

    Fraser L. Collins;Naiomy D. Rios-Arce;Jonathan D. Schepper;Narayanan Parameswaran

  • Streptozotocin, Type I Diabetes Severity and Bone

    Katherine Motyl;Laura R McCabe

  • Bone and glucose metabolism: a two-way street.

    Katherine J. Motyl;Laura R. McCabe;Ann V. Schwartz

  • Loss of Bone and Wnt10b Expression in Male Type 1 Diabetic Mice Is Blocked by the Probiotic Lactobacillus reuteri.

    Jing Zhang;Katherine J. Motyl;Regina Irwin;Ormond A. MacDougald

  • Inhibition of PPARγ prevents type I diabetic bone marrow adiposity but not bone loss

    Sergiu Botolin;Laura R. McCabe

  • Probiotic Lactobacillus reuteri Prevents Postantibiotic Bone Loss by Reducing Intestinal Dysbiosis and Preventing Barrier Disruption

    Jonathan D Schepper;Fraser L Collins;Naiomy Deliz Rios-Arce;Sandi Raehtz

  • Involvement of the Gut Microbiota and Barrier Function in Glucocorticoid-Induced Osteoporosis

    Jonathan D Schepper;Fraser Collins;Naiomy Deliz Rios-Arce;Ho Jun Kang

Frequent Co-Authors

Robert A. Britton
Robert A. Britton Simon Fraser University
Janet L. Stein
Janet L. Stein University of Vermont
Gary S. Stein
Gary S. Stein University of Vermont
Jane B. Lian
Jane B. Lian University of Vermont
Andrea Amalfitano
Andrea Amalfitano Michigan State University
Edward Chung Yern Wang
Edward Chung Yern Wang Cardiff University
Vincent B. Young
Vincent B. Young University of Michigan–Ann Arbor
Vishwa Deep Dixit
Vishwa Deep Dixit Yale University
Laurie K. McCauley
Laurie K. McCauley University of Michigan–Ann Arbor
Lee A. Denson
Lee A. Denson Cincinnati Children's Hospital Medical Center

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