World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
12717
World Ranking
14920
National Ranking
177

Overview

Hyun-Mo Ryoo is affiliated with Seoul National University in South Korea and has a body of work concentrated primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their research spans various subfields including Molecular Biology, Genetics, Immunology, Oral Surgery, and Oncology.

The main topics addressed in their research include:

  • Bone Metabolism and Diseases
  • Bone health and treatments
  • Craniofacial Disorders and Treatments
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Dental Implant Techniques and Outcomes
  • Telomeres, Telomerase, and Senescence
  • RNA Interference and Gene Delivery

Hyun-Mo Ryoo has contributed to several papers with notable publications in recognized journals. Significant recent papers include:

  • "RUNX2-modifying enzymes: therapeutic targets for bone diseases" (2020), published in Experimental & Molecular Medicine
  • "GDF11 promotes osteogenesis as opposed to MSTN, and follistatin, a MSTN/GDF11 inhibitor, increases muscle mass but weakens bone" (2020), published in Proceedings of the National Academy of Sciences
  • "ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation" (2022), published in Cellular and Molecular Life Sciences
  • "Post-Translational Regulations of Transcriptional Activity of RUNX2." (2020), published in PubMed
  • "Nicotinamide enhances osteoblast differentiation through activation of the mitochondrial antioxidant defense system" (2023), published in Experimental & Molecular Medicine

Their research has appeared frequently in these publication venues:

  • Research Square (Research Square)
  • Experimental & Molecular Medicine
  • International Journal of Molecular Sciences
  • Scientific Reports
  • Proceedings of the National Academy of Sciences

Hyun-Mo Ryoo often collaborates with several co-authors, including:

  • Heein Yoon
  • Young-Dan Cho
  • Hye-Rim Shin
  • Seung Gwa Park
  • Ki-Tae Kim

Best Publications

  • Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.

    Kyeong-Sook Lee;Hyun-Jung Kim;Qing-Lin Li;Xin-Zi Chi

  • BMP-2-induced Osterix expression is mediated by Dlx5 but is independent of Runx2.

    Mi-Hye Lee;Tae-Geon Kwon;Hyo-Sang Park;John M Wozney

  • BMP-2-induced Runx2 Expression Is Mediated by Dlx5, and TGF-β1 Opposes the BMP-2-induced Osteoblast Differentiation by Suppression of Dlx5 Expression

    Mi-Hye Lee;Youn-Jeong Kim;Hyun-Jung Kim;Hyun-Dong Park

  • Critical molecular switches involved in BMP-2-induced osteogenic differentiation of mesenchymal cells

    Hyun-Mo Ryoo;Mi-Hye Lee;Youn-Jeong Kim

  • Bone morphogenetic protein-2 stimulates RUNX2 acetylation

    Eun-Joo Jeon;Kwang-Youl Lee;Nam-Sook Choi;Mi-Hye Lee

  • Nano-fibrous scaffolding promotes osteoblast differentiation and biomineralization.

    Kyung Mi Woo;Ji Hae Jun;Victor J. Chen;Jihye Seo

  • Stage-Specific Expression of Dlx-5 during Osteoblast Differentiation: Involvement in Regulation of Osteocalcin Gene Expression

    H. M. Ryoo;H. M. Ryoo;H. M. Hoffmann;T. Beumer;B. Frenkel

  • Transient upregulation of CBFA1 in response to bone morphogenetic protein-2 and transforming growth factor beta1 in C2C12 myogenic cells coincides with suppression of the myogenic phenotype but is not sufficient for osteoblast differentiation.

    Mi Hye Lee;Amjad Javed;Hyun Jung Kim;Hong In Shin

  • Expression patterns of bone-related proteins during osteoblastic differentiation in MC3T3-E1 cells.

    Je Yong Choi;Byung Heon Lee;Keun Bae Song;Rang Woon Park

  • The Protein Kinase C Pathway Plays a Central Role in the Fibroblast Growth Factor-stimulated Expression and Transactivation Activity of Runx2

    Hyun-Jung Kim;Jung-Hwan Kim;Suk-Chul Bae;Je-Yong Choi

  • Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter.

    Mi-Hye Lee;Youn-Jeong Kim;Won-Joon Yoon;Jee-In Kim

  • Bone morphogenetic protein-2-induced alkaline phosphatase expression is stimulated by Dlx5 and repressed by Msx2.

    Youn-Jeong Kim;Mi-Hye Lee;John M. Wozney;Je-Yoel Cho

  • A comparison of craniofacial morphology in patients with and without facial asymmetry--a three-dimensional analysis with computed tomography.

    T.-G. Kwon;H.-S. Park;H.-M. Ryoo;S.-H. Lee

  • Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis.

    Thomas Åberg;Xiu-Ping Wang;Jung-Hwan Kim;Takashi Yamashiro

  • BMP2 Protein Regulates Osteocalcin Expression via Runx2-mediated Atf6 Gene Transcription

    Won Gu Jang;Eun Jung Kim;Don-Kyu Kim;Hyun-Mo Ryoo

  • Identification of putative serum glycoprotein biomarkers for human lung adenocarcinoma by multilectin affinity chromatography and LC‐MS/MS

    Sun-Hee Heo;Seung-Jin Lee;Hyun-Mo Ryoo;Jae-Yong Park

  • BMP2-activated Erk/MAP kinase stabilizes Runx2 by increasing p300 levels and histone acetyltransferase activity.

    Ji Hae Jun;Won-Joon Yoon;Sang-Beom Seo;Kyung-Mi Woo

  • Tumor necrosis factor-α increases alkaline phosphatase expression in vascular smooth muscle cells via MSX2 induction

    Hye-Lim Lee;Kyung Mi Woo;Hyun-Mo Ryoo;Jeong-Hwa Baek

  • FGF2-activated ERK Mitogen-activated Protein Kinase Enhances Runx2 Acetylation and Stabilization

    Ok-Jin Park;Hyun-Jung Kim;Kyung-Mi Woo;Jeong-Hwa Baek

  • Runx2 regulates FGF2-induced Bmp2 expression during cranial bone development.

    Kang-Young Choi;Hyun-Jung Kim;Mi-Hye Lee;Tae-Geon Kwon

Frequent Co-Authors

Je-Yong Choi
Je-Yong Choi Kyungpook National University
Gary S. Stein
Gary S. Stein University of Vermont
In-San Kim
In-San Kim Korea Institute of Science and Technology
Janet L. Stein
Janet L. Stein University of Vermont
Jane B. Lian
Jane B. Lian University of Vermont
John M. Wozney
John M. Wozney Pfizer (Canada)
Toshihisa Komori
Toshihisa Komori Nagasaki University
Haruhiko Akiyama
Haruhiko Akiyama Gifu University
Minoru Yoshida
Minoru Yoshida University of Tokyo
Peter X. Ma
Peter X. Ma University of Michigan–Ann Arbor

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry in the USA opens doors to a wide range of healthcare and life science careers. Many students complement their studies with specialized online programs that offer convenience and flexibility to fit different schedules and lifestyles.

For those interested in imaging and diagnostic roles, online radiology tech programs are a popular pathway. These programs prepare graduates for positions in hospitals and clinics, with a focus on practical, job-ready skills.

Nutrition is another strong career route. With dietetics masters programs, students can advance into roles such as clinical nutritionist, wellness coach, or community health advocate.

Those looking to enter healthcare quickly might consider online medical assistant programs fafsa approved, which can be completed in a short time and are eligible for federal financial aid. For current medical assistants aiming for career advancement, the cma to lpn bridge program online provides a structured pathway to becoming a Licensed Practical Nurse.

These related programs give biology and biochemistry students practical opportunities to apply their knowledge and strengthen their career prospects in the dynamic field of healthcare.

Best Scientists Citing Hyun-Mo Ryoo

Trending Scientists