Renny T. Franceschi

Research.com Recognitions

• 2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential.

  Dian Wang;Kurt Christensen;Kanwal Chawla;Guozhi Xiao

  808
  Citations

• MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1.

  Guozhi Xiao;Di Jiang;Peedikayil Thomas;M.Douglas Benson

  698
  Citations

• Cell-interactive Alginate Hydrogels for Bone Tissue Engineering

  E. Alsberg;K.W. Anderson;A. Albeiruti;R.T. Franceschi

  696
  Citations

• Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells.

  Renny T. Franceschi;Bhanumathi S. Iyer

  671
  Citations

• Regulation of the osteoblast-specific transcription factor, Runx2: Responsiveness to multiple signal transduction pathways

  Renny T. Franceschi;Guozhi Xiao

  668
  Citations

• Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells.

  Guozhi Xiao;Rajaram Gopalakrishnan;Di Jiang;Elizabeth Reith

  644
  Citations

• Engineering new bone tissue in vitro on highly porous poly(α-hydroxyl acids)/hydroxyapatite composite scaffolds

  Peter X. Ma;Ruiyun Zhang;Guozhi Xiao;Renny T. Franceschi

  584
  Citations

• Transcriptional regulation of osteoblasts.

  Renny T. Franceschi;Chunxi Ge;Guozhi Xiao;Hernan Roca

  547
  Citations

• Effects of ascorbic acid on collagen matrix formation and osteoblast differentiation in murine MC3T3-E1 cells.

  Renny T. Franceschi;Bhanumathi S. Iyer;Yingqi Cui

  536
  Citations

• Critical role of the extracellular signal–regulated kinase–MAPK pathway in osteoblast differentiation and skeletal development

  Chunxi Ge;Guozhi Xiao;Di Jiang;Renny T. Franceschi

  531
  Citations

• Inhibition of osteoblastic bone formation by nuclear factor-kappaB.

  Jia Chang;Zhuo Wang;Eric Tang;Zhipeng Fan

  520
  Citations

• Fibroblast Growth Factor 2 Induction of the Osteocalcin Gene Requires MAPK Activity and Phosphorylation of the Osteoblast Transcription Factor, Cbfa1/Runx2

  Guozhi Xiao;Di Jiang;Rajaram Gopalakrishnan;Renny T. Franceschi

  467
  Citations

• Role of the α2-Integrin in Osteoblast-specific Gene Expression and Activation of the Osf2 Transcription Factor

  Guozhi Xiao;Dian Wang;M. Douglas Benson;Gerard Karsenty

  461
  Citations

• BMP Signaling Is Required for RUNX2-Dependent Induction of the Osteoblast Phenotype

  Mattabhorn Phimphilai;Zhouran Zhao;Heidi Boules;Hernan Roca

  448
  Citations

• The developmental control of osteoblast-specific gene expression: role of specific transcription factors and the extracellular matrix environment.

  R.T. Franceschi

  334
  Citations

• Gene therapy-directed osteogenesis: BMP-7-transduced human fibroblasts form bone in vivo.

  Paul H. Krebsbach;Keni Gu;Renny T. Franceschi;R. Bruce Rutherford

  331
  Citations

• Gene therapy for bone formation: in vitro and in vivo osteogenic activity of an adenovirus expressing BMP7.

  Renny T. Franceschi;Dian Wang;Paul H. Krebsbach;R. Bruce Rutherford

  327
  Citations

• Multiple Signaling Pathways Converge on the Cbfa1/Runx2 Transcription Factor to Regulate Osteoblast Differentiation

  Renny T. Franceschi;Guozhi Xiao;Di Jiang;Rajaram Gopalakrishnan

  316
  Citations

• Engineered bone development from a pre-osteoblast cell line on three-dimensional scaffolds.

  Lonnie D. Shea;Dian Wang;Renny T. Franceschi;David J. Mooney

  302
  Citations

• In vitro and in vivo synergistic interactions between the Runx2/Cbfa1 transcription factor and bone morphogenetic protein-2 in stimulating osteoblast differentiation.

  Shuying Yang;Daoyan Wei;Daoyan Wei;Dian Wang;Mattabhorn Phimphilai

  294
  Citations