D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 60 Citations 15,648 138 World Ranking 7774 National Ranking 3543

Research.com Recognitions

Awards & Achievements

2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

Renny T. Franceschi mostly deals with Osteoblast, Molecular biology, Osteocalcin, Cellular differentiation and Cell biology. His Osteoblast study combines topics in areas such as Transcription factor, Bone morphogenetic protein and MAPK/ERK pathway. His Molecular biology research includes elements of Bone morphogenetic protein 7 and Genetic enhancement.

His studies deal with areas such as Type I collagen and Regulation of gene expression as well as Osteocalcin. His Cellular differentiation research focuses on Integrin and how it connects with Cell adhesion and Immunology. His work focuses on many connections between Cell biology and other disciplines, such as Bone sialoprotein, that overlap with his field of interest in Bone tissue, Scaffold and Tissue engineering.

His most cited work include:

  • Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential. (533 citations)
  • MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1. (481 citations)
  • Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells. (472 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Osteoblast, Cell biology, RUNX2, Molecular biology and Internal medicine. His Osteoblast research is multidisciplinary, relying on both Osteocalcin, Extracellular matrix, Parathyroid hormone and Cellular differentiation. His studies in Cell biology integrate themes in fields like Immunology, Bone regeneration and Bone morphogenetic protein.

His RUNX2 study integrates concerns from other disciplines, such as ATF4, Bone cell, SMAD and MAPK/ERK pathway. He has researched MAPK/ERK pathway in several fields, including Cancer research and Protein kinase A. The concepts of his Molecular biology study are interwoven with issues in Luciferase, Transfection, Bone sialoprotein, Regulation of gene expression and Binding site.

He most often published in these fields:

  • Osteoblast (45.08%)
  • Cell biology (33.61%)
  • RUNX2 (26.23%)

What were the highlights of his more recent work (between 2014-2021)?

  • Controlled release (7.38%)
  • Biomedical engineering (12.30%)
  • Acoustic droplet vaporization (7.38%)

In recent papers he was focusing on the following fields of study:

His main research concerns Controlled release, Biomedical engineering, Acoustic droplet vaporization, Fibrin and Osteoblast. Within one scientific family, Renny T. Franceschi focuses on topics pertaining to Transgene under Fibrin, and may sometimes address concerns connected to Surgery, Hyperthermia and Regulation of gene expression. Specifically, his work in Osteoblast is concerned with the study of RUNX2.

His RUNX2 research includes themes of Endocrinology, Epigenetics and Internal medicine. His work carried out in the field of Extracellular matrix brings together such families of science as Apatite, Mineralogy and Ultrastructure. His Transcription factor study combines topics from a wide range of disciplines, such as Chromatin and Phosphorylation, Cell biology.

Between 2014 and 2021, his most popular works were:

  • Reciprocal Control of Osteogenic and Adipogenic Differentiation by ERK/MAP Kinase Phosphorylation of Runx2 and PPARγ Transcription Factors (65 citations)
  • DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis (58 citations)
  • Mesenchymal Stem Cell-Induced DDR2 Mediates Stromal-Breast Cancer Interactions and Metastasis Growth (56 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Cancer research, Scaffold, Controlled release, Fibrin and Acoustic droplet vaporization are his primary areas of study. Renny T. Franceschi has included themes like Prostate, LNCaP, PCA3, Prostate cancer and Metastasis in his Cancer research study. The various areas that Renny T. Franceschi examines in his Metastasis study include Stromal cell, Cell growth, Downregulation and upregulation, Signal transduction and Mesenchymal stem cell.

His Scaffold research incorporates elements of Tissue engineering and Dextran. His research on Biophysics frequently connects to adjacent areas such as Osteoblast. His study in Osteoblast is interdisciplinary in nature, drawing from both Phosphorylation and MAPK/ERK pathway.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential.

Dian Wang;Kurt Christensen;Kanwal Chawla;Guozhi Xiao.
Journal of Bone and Mineral Research (1999)

731 Citations

MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1.

Guozhi Xiao;Di Jiang;Peedikayil Thomas;M.Douglas Benson.
Journal of Biological Chemistry (2000)

651 Citations

Cell-interactive Alginate Hydrogels for Bone Tissue Engineering

E. Alsberg;K.W. Anderson;A. Albeiruti;R.T. Franceschi.
Journal of Dental Research (2001)

647 Citations

Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells.

Renny T. Franceschi;Bhanumathi S. Iyer.
Journal of Bone and Mineral Research (2009)

617 Citations

Regulation of the osteoblast-specific transcription factor, Runx2: Responsiveness to multiple signal transduction pathways

Renny T. Franceschi;Guozhi Xiao.
Journal of Cellular Biochemistry (2003)

613 Citations

Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells.

Guozhi Xiao;Rajaram Gopalakrishnan;Di Jiang;Elizabeth Reith.
Journal of Bone and Mineral Research (2002)

611 Citations

Engineering new bone tissue in vitro on highly porous poly(α-hydroxyl acids)/hydroxyapatite composite scaffolds

Peter X. Ma;Ruiyun Zhang;Guozhi Xiao;Renny T. Franceschi.
Journal of Biomedical Materials Research (2001)

577 Citations

Effects of ascorbic acid on collagen matrix formation and osteoblast differentiation in murine MC3T3-E1 cells.

Renny T. Franceschi;Bhanumathi S. Iyer;Yingqi Cui.
Journal of Bone and Mineral Research (2009)

500 Citations

Critical role of the extracellular signal–regulated kinase–MAPK pathway in osteoblast differentiation and skeletal development

Chunxi Ge;Guozhi Xiao;Di Jiang;Renny T. Franceschi.
Journal of Cell Biology (2007)

465 Citations

Inhibition of osteoblastic bone formation by nuclear factor-kappaB.

Jia Chang;Zhuo Wang;Eric Tang;Zhipeng Fan.
Nature Medicine (2009)

460 Citations

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