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Molecular Biology

D-Index
117
Citations
46876
World Ranking
291
National Ranking
175

Overview

Andre J. Van Wijnen is affiliated with the University of Vermont in the United States. Their research spans multiple fields with a primary focus on medicine and biochemistry, genetics, and molecular biology. Within these domains, they have concentrated extensively on molecular biology, surgery, genetics, rheumatology, and cancer research.

Their scholarly contributions address a variety of topics, including:

  • Epigenetics and DNA methylation
  • Mesenchymal stem cell research
  • Osteoarthritis treatment and mechanisms
  • Cancer-related gene regulation
  • Total knee arthroplasty outcomes
  • Tendon structure and treatment
  • Knee injuries and reconstruction techniques

Andre J. Van Wijnen's publication record includes notable recent papers such as:

  • "The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes," 2021, Clinical Epigenetics
  • "Biomedical Applications of Microfluidic Devices: A Review," 2022, Biosensors
  • "Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development," 2020, Bone
  • "Vitamin C epigenetically controls osteogenesis and bone mineralization," 2022, Nature Communications
  • "Hypoxic preconditioning induces epigenetic changes and modifies swine mesenchymal stem cell angiogenesis and senescence in experimental atherosclerotic renal artery stenosis," 2021, Stem Cell Research & Therapy

The researcher has frequently published in several academic venues, including:

  • Gene
  • Bone Reports
  • Bone
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)

Collaborative work is a significant aspect of their research approach. Frequent coauthors include:

  • Amel Dudakovic
  • Roman Thaler
  • Matthew P. Abdel
  • Daniel M. Berry
  • Christopher R. Paradise

Their research output reflects engagement with both fundamental and applied biomedical sciences, with ongoing interests in epigenetics, stem cell biology, and skeletal biology.

Best Publications

  • Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

    Clotilde Théry;Kenneth W. Witwer;Elena Aikawa;Maria Jose Alcaraz

  • Canonical WNT Signaling Promotes Osteogenesis by Directly Stimulating Runx2 Gene Expression

    Tripti Gaur;Christopher J. Lengner;Hayk Hovhannisyan;Ramesh A. Bhat

  • Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation

    Zhaoyong Li;Mohammad Q. Hassan;Mohammed Jafferji;Rami I. Aqeilan

  • A microRNA signature for a BMP2-induced osteoblast lineage commitment program.

    Zhaoyong Li;Mohammad Q. Hassan;Stefano Volinia;Andre J. van Wijnen

  • Concise Review: Multifaceted Characterization of Human Mesenchymal Stem Cells for Use in Regenerative Medicine.

    Rebekah M. Samsonraj;Michael Raghunath;Victor Nurcombe;James H. Hui

  • Expression of the osteoblast differentiation factor RUNX2 (Cbfa1/AML3/Pebp2αA) is inhibited by tumor necrosis factor-α

    Linda C. Gilbert;Xiaofei He;Paul K. Farmer;Janet Rubin

  • Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

    Jane B. Lian;Amjad Javed;S. Kaleem Zaidi;Christopher Lengner

  • Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase

    Klaus A. Becker;Prachi N. Ghule;Jaclyn A. Therrien;Jane B. Lian

  • A current review of molecular mechanisms regarding osteoarthritis and pain

    Andrew S. Lee;Michael B. Ellman;Dongyao Yan;Jeffrey S. Kroin

  • Tyrosine phosphorylation controls Runx2‐mediated subnuclear targeting of YAP to repress transcription

    Sayyed K. Zaidi;Andrew J. Sullivan;Ricardo F. Medina;Yoshiaki Ito

  • Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter.

    Jennifer J. Westendorf;S. Kaleem Zaidi;Jonathan E. Cascino;Rachel Kahler

  • The Runx2 Osteogenic Transcription Factor Regulates Matrix Metalloproteinase 9 in Bone Metastatic Cancer Cells and Controls Cell Invasion

    Jitesh Pratap;Amjad Javed;Lucia R. Languino;Andre J. van Wijnen

  • MicroRNAs 221 and 222 Bypass Quiescence and Compromise Cell Survival

    Ricardo Medina;Sayyed K. Zaidi;Chang Gong Liu;Janet L. Stein

  • Runx2 association with progression of prostate cancer in patients: Mechanisms mediating bone osteolysis and osteoblastic metastatic lesions

    J. Akech;J. J. Wixted;K. Bedard;M. Van Der Deen

  • Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors

    Congmei Zeng;Andre J. Van Wijnen;Janet L. Stein;Shari Meyers

  • Transient upregulation of CBFA1 in response to bone morphogenetic protein-2 and transforming growth factor beta1 in C2C12 myogenic cells coincides with suppression of the myogenic phenotype but is not sufficient for osteoblast differentiation.

    Mi Hye Lee;Amjad Javed;Hyun Jung Kim;Hong In Shin

  • The Tissue-Specific Nuclear Matrix Protein, NMP-2, Is a Member of the AML/ CBF/PEBP2/Runt Domain Transcription Factor Family: Interactions with the Osteocalcin Gene Promoter

    Harold L. Merriman;Andre J. Van Wijnen;Scott W. Hiebert;Joseph P. Bidwell

  • Dlx3 Transcriptional Regulation of Osteoblast Differentiation: Temporal Recruitment of Msx2, Dlx3, and Dlx5 Homeodomain Proteins to Chromatin of the Osteocalcin Gene

    Mohammad Q. Hassan;Amjad Javed;Maria I. Morasso;Jeremy Karlin

  • Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites

    Sayyed K. Zaidi;Andrew J. Sullivan;Andre J. van Wijnen;Janet L. Stein

  • A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2

    Y. Zhang;Rong-lin Xie;Janet L. Stein;Jane B. Lian

Frequent Co-Authors

Gary S. Stein
Gary S. Stein University of Vermont
Janet L. Stein
Janet L. Stein University of Vermont
Jane B. Lian
Jane B. Lian University of Vermont
Martin Montecino
Martin Montecino Andrés Bello University
Amjad Javed
Amjad Javed University of Alabama at Birmingham
Sayyed K. Zaidi
Sayyed K. Zaidi University of Vermont
Je-Yong Choi
Je-Yong Choi Kyungpook National University
Simon M. Cool
Simon M. Cool University of Queensland
Christopher J. Lengner
Christopher J. Lengner University of Pennsylvania
Hee-Jeong Im
Hee-Jeong Im University of Illinois at Chicago

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