Her primary areas of study are Cell biology, Cartilage, Osteoblast, Bone morphogenetic protein and Cellular differentiation. Her Cell biology study combines topics from a wide range of disciplines, such as Internal medicine, Biochemistry and Endocrinology. The Chondrocyte research Di Chen does as part of her general Cartilage study is frequently linked to other disciplines of science, such as Aggrecan, therefore creating a link between diverse domains of science.
The concepts of her Osteoblast study are interwoven with issues in Bone morphogenetic protein 7, Bone morphogenetic protein 2 and Proteasome. The study incorporates disciplines such as Molecular biology and Noggin in addition to Bone morphogenetic protein 2. The various areas that Di Chen examines in her Cellular differentiation study include Mesenchymal stem cell and BMP signaling pathway.
Her primary scientific interests are in Cell biology, Cartilage, Internal medicine, Chondrocyte and Endocrinology. Her Cell biology study integrates concerns from other disciplines, such as Cellular differentiation and Osteoblast. Her study in Osteoblast is interdisciplinary in nature, drawing from both Osteoclast, Ubiquitin ligase, Bone morphogenetic protein 2 and Cancer research.
Her work deals with themes such as Immunohistochemistry, Pathology, Bioinformatics and Conditional gene knockout, which intersect with Cartilage. Her research investigates the link between Chondrocyte and topics such as Molecular biology that cross with problems in Transcription factor and Bone morphogenetic protein 4. Her Endocrinology research is multidisciplinary, relying on both Downregulation and upregulation, Bone morphogenetic protein 7 and Transgene.
Di Chen spends much of her time researching Cell biology, Cartilage, Pathogenesis, Internal medicine and Pathology. Her Cell biology research is multidisciplinary, incorporating elements of Osteoclast and Osteoblast. She combines subjects such as Bone growth and Bone marrow with her study of Osteoblast.
Her Cartilage research integrates issues from Immunohistochemistry, Condyle, Arthritis, MMP3 and Stem cell. She interconnects Lumbar and Endocrinology in the investigation of issues within Internal medicine. Her studies in Pathology integrate themes in fields like Phenotype and Synovitis.
Her main research concerns Cell biology, Cartilage, Downregulation and upregulation, Endocrinology and Internal medicine. Her Cell biology research is multidisciplinary, relying on both Bone morphogenetic protein, RUNX2, Tissue homeostasis and Intervertebral disc. Her work deals with themes such as NFKB1, Transcription factor and NF-κB, Signal transduction, which intersect with Cartilage.
The various areas that Di Chen examines in her Downregulation and upregulation study include Immunohistochemistry, CRISPR, Bioinformatics, Nerve growth factor and Histology. Her Endocrinology study frequently links to adjacent areas such as MMP3. When carried out as part of a general Internal medicine research project, her work on Adipocyte, Matrix metalloproteinase and Adipose tissue is frequently linked to work in Leptin, therefore connecting diverse disciplines of study.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Stimulation of bone formation in vitro and in rodents by statins.
G. Mundy;R. Garrett;S. Harris;J. Chan.
Science (1999)
MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation.
Jian Huang;Lan Zhao;Lianping Xing;Di Chen.
Stem Cells (2009)
Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice
Mei Zhu;Dezhi Tang;Dezhi Tang;Qiuqian Wu;Suyang Hao.
Journal of Bone and Mineral Research (2009)
Osteoarthritis: toward a comprehensive understanding of pathological mechanism.
Di Chen;Jie Shen;Weiwei Zhao;Weiwei Zhao;Tingyu Wang.
Bone research (2017)
The BMP signaling and in vivo bone formation
Xu Cao;Di Chen.
Gene (2005)
Smad5 and DPC4 Are Key Molecules in Mediating BMP-2-induced Osteoblastic Differentiation of the Pluripotent Mesenchymal Precursor Cell Line C2C12
Riko Nishimura;Riko Nishimura;Yoichi Kato;Di Chen;Stephen E. Harris.
Journal of Biological Chemistry (1998)
Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro
I.R. Garrett;D. Chen;G. Gutierrez;M. Zhao.
Journal of Clinical Investigation (2003)
E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation
Ming Zhao;Mei Qiao;Babatunde O. Oyajobi;Gregory R. Mundy.
Journal of Biological Chemistry (2003)
BONE MORPHOGENETIC PROTEIN 2 (BMP-2) ENHANCES BMP-3, BMP-4, AND BONE CELL DIFFERENTIATION MARKER GENE EXPRESSION DURING THE INDUCTION OF MINERALIZED BONE MATRIX FORMATION IN CULTURES OF FETAL RAT CALVARIAL OSTEOBLASTS
D. Chen;M. A. Harris;G. Rossini;C. R. Dunstan.
Calcified Tissue International (1997)
MMP13 is a critical target gene during the progression of osteoarthritis
Meina Wang;Meina Wang;Erik R Sampson;Hongting Jin;Hongting Jin;Jia Li;Jia Li.
Arthritis Research & Therapy (2013)
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