World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
25668
World Ranking
3156
National Ranking
86

Di Chen publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Di Chen sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 269 publications — 72nd percentile

72% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Di Chen D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Di Chen sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 85 D-Index — 84th percentile

84% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Di Chen is affiliated with the Chinese Academy of Sciences in China and has a research portfolio primarily focused on Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several key subfields including Molecular Biology, Rheumatology, Genetics, Oncology, and Surgery.

Their research addresses a range of biomedical topics, notably in osteoarthritis treatment and mechanisms, bone metabolism and diseases, and spine and intervertebral disc pathology. Other significant subject areas include cell adhesion molecules research, glioma diagnosis and treatment, musculoskeletal pain and rehabilitation, as well as inflammatory mediators and NSAID effects.

Di Chen has contributed to multiple recent scientific publications, with selected papers including:

  • Metformin limits osteoarthritis development and progression through activation of AMPK signalling, 2020, Annals of the Rheumatic Diseases
  • Modifiable risk factors associated with cardiovascular disease and mortality in China: a PURE substudy, 2022, European Heart Journal
  • Risk of metabolic abnormalities in osteoarthritis: a new perspective to understand its pathological mechanisms, 2023, Bone Research
  • Osteoarthritis Pain, 2022, International Journal of Molecular Sciences
  • Morroniside attenuates apoptosis and pyroptosis of chondrocytes and ameliorates osteoarthritic development by inhibiting NF-κB signaling, 2020, Journal of Ethnopharmacology

The scientist frequently publishes in well-regarded journals such as Bone Research, Journal of Orthopaedic Translation, Nature Communications, Theranostics, and Journal of Neurorestoratology. Their publication record shows repeated contributions, for example, seven papers in Bone Research and multiple papers in other venues.

Throughout their career, Di Chen has collaborated extensively with other researchers, including Guozhi Xiao, Huiling Cao, Hongting Jin, Xiaohao Wu, and Yumei Lai, with whom they have coauthored several papers.

Best Publications

  • Osteoarthritis: toward a comprehensive understanding of pathological mechanism.

    Di Chen;Jie Shen;Weiwei Zhao;Tingyu Wang

  • Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice

    Mei Zhu;Dezhi Tang;Dezhi Tang;Qiuqian Wu;Suyang Hao

  • MMP13 is a critical target gene during the progression of osteoarthritis

    Meina Wang;Meina Wang;Erik R Sampson;Hongting Jin;Hongting Jin;Jia Li;Jia Li

  • Osteoarthritis Pathogenesis: A Review of Molecular Mechanisms

    Bingjiang Xia;Di Chen;Di Chen;Jushi Zhang;Songfeng Hu

  • The BMP signaling and in vivo bone formation

    Xu Cao;Di Chen

  • Smad5 and DPC4 Are Key Molecules in Mediating BMP-2-induced Osteoblastic Differentiation of the Pluripotent Mesenchymal Precursor Cell Line C2C12

    Riko Nishimura;Yoichi Kato;Di Chen;Stephen E. Harris

  • Ankylosing spondylitis: etiology, pathogenesis, and treatments

    Wei Zhu;Xuxia He;Kaiyuan Cheng;Linjie Zhang

  • E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation

    Ming Zhao;Mei Qiao;Babatunde O. Oyajobi;Gregory R. Mundy

  • Intestinal epithelial vitamin D receptor deletion leads to defective autophagy in colitis

    Shaoping Wu;Yong Guo Zhang;Rong Lu;Yinglin Xia

  • Tumor Necrosis Factor Promotes Runx2 Degradation through Up-regulation of Smurf1 and Smurf2 in Osteoblasts

    Hiroyuki Kaneki;Ruolin Guo;Di Chen;Zhenqiang Yao

  • Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts

    Rongrong Zhang;Babatunde O. Oyajobi;Stephen E. Harris;Di Chen

  • Inhibition of β-Catenin Signaling in Articular Chondrocytes Results in Articular Cartilage Destruction

    Mei Zhu;Mo Chen;Michael Zuscik;Qiuqian Wu

  • Regulation of chondrogenesis and chondrocyte differentiation by stress

    Michael J. Zuscik;Matthew J Hilton;Xinping Zhang;Di Chen

  • MEPE has the properties of an osteoblastic phosphatonin and minhibin

    P.S.N Rowe;Y Kumagai;G Gutierrez;I.R Garrett

  • BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development

    Bing Shu;Ming Zhang;Rong Xie;Meina Wang

  • Dual effects of macrophage inflammatory protein-1α on osteolysis and tumor burden in the murine 5TGM1 model of myeloma bone disease

    Babatunde O. Oyajobi;Giovanni Franchin;Paul J. Williams;Donna Pulkrabek

  • Smurf1 Inhibits Osteoblast Differentiation and Bone Formation in Vitro and in Vivo

    Ming Zhao;Mei Qiao;Stephen E. Harris;Babatunde O. Oyajobi

  • TGF-β signaling and the development of osteoarthritis.

    Jie Shen;Shan Li;Di Chen

  • Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis

    Meina Wang;Jie Shen;Hongting Jin;Hongting Jin;Hee Jeong Im

  • Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway.

    Song Ho Chang;Daisuke Mori;Hiroshi Kobayashi;Yoshifumi Mori;Yoshifumi Mori

Frequent Co-Authors

Guozhi Xiao
Guozhi Xiao Southern University of Science and Technology
Regis J. O'Keefe
Regis J. O'Keefe Washington University in St. Louis
Hee-Jeong Im
Hee-Jeong Im University of Illinois at Chicago
Michael J. Zuscik
Michael J. Zuscik University of Rochester
Gregory R. Mundy
Gregory R. Mundy Vanderbilt University
Howard S. An
Howard S. An Rush University Medical Center
Brendan F. Boyce
Brendan F. Boyce University of Rochester Medical Center
Edward M. Schwarz
Edward M. Schwarz University of Rochester Medical Center
Hicham Drissi
Hicham Drissi Emory University
Chu-Xia Deng
Chu-Xia Deng University of Macau

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