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Biology and Biochemistry

D-Index
66
Citations
21118
World Ranking
8495
National Ranking
623

Overview

Frank Westermann is affiliated with the German Cancer Research Center in Germany. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine.

The primary fields of study in their work include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their subfields of study further focus on:

  • Molecular Biology
  • Neurology
  • Cancer Research
  • Oncology
  • Genetics

Westermann's research topics highlight specific scientific and medical problems, consisting of:

  • Neuroblastoma Research and Treatments
  • Cancer, Hypoxia, and Metabolism
  • Glioma Diagnosis and Treatment
  • Cancer Genomics and Diagnostics
  • Epigenetics and DNA Methylation
  • Protein Degradation and Inhibitors
  • Single-cell and spatial transcriptomics

The scientist has contributed to academic journals and publication venues repeatedly, among which the most frequent are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Blood
  • Neuro-Oncology
  • British Journal of Cancer

Recent publications include:

  • "Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma," 2021, Nature Genetics
  • "The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets," 2021, Cancer Discovery
  • "MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis," 2022, Nature Cancer
  • "Ferroptosis in health and disease," 2024, Redox Biology
  • "Super enhancers define regulatory subtypes and cell identity in neuroblastoma," 2020, Nature Cancer

Frequent co-authors working alongside Westermann include:

  • Stefan M. Pfister
  • Till Milde
  • Sabine Stainczyk
  • Umut H. Toprak
  • Kai-Oliver Henrich

Best Publications

  • Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks

    Javed Khan;Jun S. Wei;Markus Ringnér;Markus Ringnér;Lao H. Saal

  • miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

    Li Ma;Jennifer Young;Harsha Prabhala;Elizabeth Pan

  • The landscape of genomic alterations across childhood cancers

    Susanne N. Gröbner;Barbara C. Worst;Joachim Weischenfeldt;Joachim Weischenfeldt;Ivo Buchhalter

  • The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

    Leming Shi;Gregory Campbell;Wendell D. Jones;Fabien Campagne

  • A novel and universal method for microRNA RT-qPCR data normalization

    Pieter Mestdagh;Pieter Van Vlierberghe;An-Sofie De Weer;Daniel Muth

  • Telomerase activation by genomic rearrangements in high-risk neuroblastoma

    Martin Peifer;Falk Hertwig;Frederik Roels;Daniel Dreidax

  • Histone Deacetylase 8 in Neuroblastoma Tumorigenesis

    Ina Oehme;Hedwig E. Deubzer;Dennis Wegener;Diana Pickert

  • Neuroblastoma: biology and molecular and chromosomal pathology

    Manfred Schwab;Frank Westermann;Barbara Hero;Frank Berthold

  • Customized Oligonucleotide Microarray Gene Expression–Based Classification of Neuroblastoma Patients Outperforms Current Clinical Risk Stratification

    André Oberthuer;Frank Berthold;Patrick Warnat;Barbara Hero

  • Mutational dynamics between primary and relapse neuroblastomas

    Alexander Schramm;Johannes Köster;Johannes Köster;Yassen Assenov;Kristina Althoff

  • Next-generation personalised medicine for high-risk paediatric cancer patients – The INFORM pilot study

    Barbara C. Worst;Barbara C. Worst;Cornelis M. van Tilburg;Gnana Prakash Balasubramanian;Petra Fiesel;Petra Fiesel

  • Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas

    Frank Westermann;Daniel Muth;Axel Benner;Tobias Bauer

  • A mechanistic classification of clinical phenotypes in neuroblastoma

    Sandra Ackermann;Sandra Ackermann;Maria Cartolano;Barbara Hero;Anne Welte;Anne Welte

  • Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia

    Peter Nürnberg;Holger Thiele;Holger Thiele;David Chandler;Wolfgang Höhne

  • Prediction of Clinical Outcome Using Gene Expression Profiling and Artificial Neural Networks for Patients with Neuroblastoma

    Javed Khan;Jun S. Wei;Braden T. Greer

  • Genetic parameters of neuroblastomas

    Frank Westermann;Manfred Schwab

  • Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma

    H Kocak;S Ackermann;B Hero;Y Kahlert

  • Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma.

    Selina Jansky;Selina Jansky;Ashwini Kumar Sharma;Verena Körber;Andrés Quintero

  • FSTL5 Is a Marker of Poor Prognosis in Non-WNT/Non-SHH Medulloblastoma

    Marc Remke;Thomas Hielscher;Andrey Korshunov;Andrey Korshunov;Paul A. Northcott

  • A mechanistic classification of clinical phenotypes in neuroblastoma

    S Ackermann;M Cartolano;B Hero;A Roderwieser

Frequent Co-Authors

Matthias Fischer
Matthias Fischer University of Cologne
Johannes H. Schulte
Johannes H. Schulte Charité - University Medicine Berlin
Manfred Schwab
Manfred Schwab German Cancer Research Center
Frank Berthold
Frank Berthold University of Cologne
Benedikt Brors
Benedikt Brors German Cancer Research Center
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Katleen De Preter
Katleen De Preter Ghent University
Jo Vandesompele
Jo Vandesompele Ghent University
Franki Speleman
Franki Speleman Ghent University
Roland Eils
Roland Eils Charité - University Medicine Berlin

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