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Medicine

D-Index
86
Citations
31719
World Ranking
13980
National Ranking
742

Overview

Frank Berthold is affiliated with the University of Cologne in Germany. Their research primarily focuses on medicine and intersects significantly with biochemistry, genetics, and molecular biology.

The scientist's work spans several specialized subfields, including neurology, molecular biology, cancer research, pediatrics, perinatology, child health, and surgery. These areas reflect a multidisciplinary approach to understanding and treating complex medical conditions.

Berthold's research topics cover a range of themes, with the greatest emphasis on neuroblastoma research and treatments. Additional topics include cancer, hypoxia, and metabolism; cancer therapeutics and mechanisms; adrenal and paraganglionic tumors; quality of life of childhood cancer survivors; acute lymphoblastic leukemia research; and neurofibromatosis and schwannoma cases.

Their recent publications highlight engagement with neuroblastoma and related clinical questions. Notable papers include:

  • Extended induction chemotherapy does not improve the outcome for high-risk neuroblastoma patients: results of the randomized open-label GPOH trial NB2004-HR (2020, Annals of Oncology)
  • The prognostic strength of serum LDH and serum ferritin in children with neuroblastoma: A report from the International Neuroblastoma Risk Group (INRG) project (2020, Pediatric Blood & Cancer)
  • Genomic ALK alterations in primary and relapsed neuroblastoma (2023, British Journal of Cancer)
  • Impact of RNA-seq data analysis algorithms on gene expression estimation and downstream prediction (2020, Scientific Reports)
  • A nomogram of clinical and biologic factors to predict survival in children newly diagnosed with high-risk neuroblastoma: An International Neuroblastoma Risk Group project (2020, Pediatric Blood & Cancer)

These publications appear in a selection of journals frequently chosen by Berthold, with the most recurrent venue being Pediatric Blood & Cancer. Other publication venues include the British Journal of Cancer, BMC Pediatrics, Annals of Oncology, and Scientific Reports.

Berthold has collaborated repeatedly with several researchers, indicating established partnerships within the scientific community. Frequent co-authors include Barbara Hero, Angela Ernst, Thorsten Simon, Matthias Fischer, and Roswitha Schumacher-Kuckelkorn.

Best Publications

  • Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks

    Javed Khan;Jun S. Wei;Markus Ringnér;Markus Ringnér;Lao H. Saal

  • Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment.

    G M Brodeur;J Pritchard;F Berthold;N L Carlsen

  • The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

    Leming Shi;Gregory Campbell;Wendell D. Jones;Fabien Campagne

  • Advances in Risk Classification and Treatment Strategies for Neuroblastoma

    Navin R. Pinto;Mark A. Applebaum;Samuel L. Volchenboum;Katherine K. Matthay

  • International criteria for diagnosis, staging, and response to treatment in patients with neuroblastoma.

    G M Brodeur;R C Seeger;A Barrett;F Berthold

  • Revisions of the international criteria for neuroblastoma diagnosis, staging and response to treatment.

    Brodeur Gm;Pritchard J;Berthold F;Carlsen Nl

  • Telomerase activation by genomic rearrangements in high-risk neuroblastoma

    Martin Peifer;Falk Hertwig;Frederik Roels;Daniel Dreidax

  • Postoperative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medulloblastoma in childhood: results of the German prospective randomized trial HIT '91.

    Rolf D. Kortmann;Joachim Kühl;Beate Timmermann;Uwe Mittler

  • NEUROBLASTOMA SCREENING AT ONE YEAR OF AGE

    Freimut H Schilling;Claudia Spix;Frank Berthold;Rudolf Erttmann

  • Myeloablative megatherapy with autologous stem-cell rescue versus oral maintenance chemotherapy as consolidation treatment in patients with high-risk neuroblastoma: a randomised controlled trial.

    Frank Berthold;Joachim Boos;Stefan Burdach;Rudolf Erttmann

  • Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched

    Torsten Pietsch;Andreas Waha;Anke Koch;Jürgen Kraus

  • Comparison of RNA-seq and microarray-based models for clinical endpoint prediction.

    Wenqian Zhang;Ying Yu;Falk Hertwig;Falk Hertwig;Jean Thierry-Mieg

  • Neuroblastoma: biology and molecular and chromosomal pathology

    Manfred Schwab;Frank Westermann;Barbara Hero;Frank Berthold

  • Customized Oligonucleotide Microarray Gene Expression–Based Classification of Neuroblastoma Patients Outperforms Current Clinical Risk Stratification

    André Oberthuer;Frank Berthold;Patrick Warnat;Barbara Hero

  • [Corticosteroid-dependent reduction of leukocyte count in blood as a prognostic factor in acute lymphoblastic leukemia in childhood (therapy study ALL-BFM 83)].

    H. Riehm;A. Reiter;M. Schrappe;F. Berthold

  • Localized Infant Neuroblastomas Often Show Spontaneous Regression: Results of the Prospective Trials NB95-S and NB97

    Barbara Hero;Thorsten Simon;Ruediger Spitz;Karen Ernestus

  • Clinical and Biologic Features Predictive of Survival After Relapse of Neuroblastoma: A Report From the International Neuroblastoma Risk Group Project

    Wendy B. London;Victoria Castel;Tom Monclair;Peter F. Ambros

  • Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas.

    R P Dahmen;A Koch;D Denkhaus;J C Tonn

  • Clinical Significance of Tumor-Associated Inflammatory Cells in Metastatic Neuroblastoma

    Shahab Asgharzadeh;Jill A. Salo;Lingyun Ji;André Oberthuer

  • A mechanistic classification of clinical phenotypes in neuroblastoma

    Sandra Ackermann;Sandra Ackermann;Maria Cartolano;Barbara Hero;Anne Welte;Anne Welte

Frequent Co-Authors

Matthias Fischer
Matthias Fischer University of Cologne
Frank Westermann
Frank Westermann German Cancer Research Center
Benedikt Brors
Benedikt Brors German Cancer Research Center
Manfred Schwab
Manfred Schwab German Cancer Research Center
Roland Eils
Roland Eils Charité - University Medicine Berlin
Norbert Graf
Norbert Graf Saarland University
Otmar D. Wiestler
Otmar D. Wiestler German Cancer Research Center
Johannes H. Schulte
Johannes H. Schulte Charité - University Medicine Berlin
Katherine K. Matthay
Katherine K. Matthay University of California, San Francisco
Susan L. Cohn
Susan L. Cohn University of Chicago

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