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Biology and Biochemistry

D-Index
62
Citations
16369
World Ranking
10655
National Ranking
767

Overview

Johannes H. Schulte is affiliated with Charité - University Medicine Berlin in Germany. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with particular focus on Neurology, Molecular Biology, Oncology, Genetics, and Cancer Research.

The scientist's main research topics include:

  • Neuroblastoma Research and Treatments
  • Cancer, Hypoxia, and Metabolism
  • Cancer therapeutics and mechanisms
  • CAR-T cell therapy research
  • Virus-based gene therapy research
  • Hematopoietic Stem Cell Transplantation
  • Cytomegalovirus and herpesvirus research

Johannes H. Schulte has contributed to several recent papers, including:

  • Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers, 2020, Nature Genetics
  • Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma, 2020, Nature Communications
  • Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions, 2021, Nature Communications
  • Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma, 2020, European Journal of Cancer
  • Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells, 2023, Nature Genetics

Frequent co-authors of Johannes H. Schulte include Angelika Eggert, Anton G. Henssen, Hedwig E. Deubzer, Peter Lang, and Annette Künkele.

Publications have frequently appeared in venues such as bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, Nature Communications, Cancers, and the Journal of Clinical Oncology.

In addition to journal articles, Johannes H. Schulte has published a book titled Die hoheitliche Einbindung sachverständiger Stellen in naturwissenschaftlich-technisch komplexen Zulassungsverfahren, published by Duncker & Humblot in 2020.

Best Publications

  • The landscape of genomic alterations across childhood cancers

    Susanne N. Gröbner;Barbara C. Worst;Joachim Weischenfeldt;Joachim Weischenfeldt;Ivo Buchhalter

  • Stabilization of N-Myc Is a Critical Function of Aurora A in Human Neuroblastoma

    Tobias Otto;Sebastian Horn;Markus Brockmann;Ursula Eilers

  • Telomerase activation by genomic rearrangements in high-risk neuroblastoma

    Martin Peifer;Falk Hertwig;Frederik Roels;Daniel Dreidax

  • Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

    Thomas F Eleveld;Derek A Oldridge;Virginie Bernard;Jan Koster

  • Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy

    Johannes H. Schulte;Soyoung Lim;Alexander Schramm;Nicolaus Friedrichs

  • LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression

    Jan J Molenaar;Raquel Domingo-Fernández;Marli E Ebus;Sven Lindner

  • Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers.

    Hoon Kim;Nam-Phuong Nguyen;Kristen Turner;Sihan Wu

  • The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma

    Pieter Mestdagh;Anna-Karin Bostrom;Francis Impens;Erik Fredlund;Erik Fredlund

  • Mutational dynamics between primary and relapse neuroblastomas

    Alexander Schramm;Johannes Köster;Johannes Köster;Yassen Assenov;Kristina Althoff

  • Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification

    Sara De Brouwer;Katleen De Preter;Candy Kumps;Piotr Zabrocki

  • Next-generation personalised medicine for high-risk paediatric cancer patients – The INFORM pilot study

    Barbara C. Worst;Barbara C. Worst;Cornelis M. van Tilburg;Gnana Prakash Balasubramanian;Petra Fiesel;Petra Fiesel

  • MYCN regulates oncogenic MicroRNAs in neuroblastoma.

    Johannes H. Schulte;Sebastian Horn;Tobias Otto;Birgit Samans

  • A mechanistic classification of clinical phenotypes in neuroblastoma

    Sandra Ackermann;Sandra Ackermann;Maria Cartolano;Barbara Hero;Anne Welte;Anne Welte

  • Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma

    Richard P. Koche;Elias Rodriguez-Fos;Konstantin Helmsauer;Martin Burkert;Martin Burkert

  • The Expanding World of N-MYC–Driven Tumors

    David S. Rickman;Johannes H. Schulte;Martin Eilers

  • Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma

    Johannes H. Schulte;Tobias Marschall;Marcel Martin;Philipp Rosenstiel

  • Histone deacetylase 10 promotes autophagy-mediated cell survival

    Ina Oehme;Jan Peter Linke;Barbara C. Böck;Till Milde;Till Milde

  • Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation.

    A Sprüssel;J H Schulte;S Weber;M Necke

  • Targeted expression of mutated ALK induces neuroblastoma in transgenic mice.

    Lukas C Heukamp;Theresa Thor;Alexander Schramm;Katleen De Preter

  • A mechanistic classification of clinical phenotypes in neuroblastoma

    S Ackermann;M Cartolano;B Hero;A Roderwieser

Frequent Co-Authors

Katleen De Preter
Katleen De Preter Ghent University
Jo Vandesompele
Jo Vandesompele Ghent University
Franki Speleman
Franki Speleman Ghent University
Rogier Versteeg
Rogier Versteeg University of Amsterdam
Frank Westermann
Frank Westermann German Cancer Research Center
Matthias Fischer
Matthias Fischer University of Cologne
Pieter Mestdagh
Pieter Mestdagh Ghent University
Raymond L. Stallings
Raymond L. Stallings Royal College of Surgeons in Ireland
Genevieve Laureys
Genevieve Laureys Ghent University Hospital
Jan Koster
Jan Koster University of Amsterdam

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