World's Best Scientists 2026 revealed!
Jo Vandesompele

Jo Vandesompele

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Genetics
Belgium
2026

D-Index & Metrics

Genetics

D-Index
106
Citations
85803
World Ranking
589
National Ranking
6

Medicine

D-Index
106
Citations
86129
World Ranking
6350
National Ranking
72

Research.com Recognitions

  • 2026 - Research.com Genetics in Belgium Leader Award
  • 2025 - Research.com Genetics in Belgium Leader Award
  • 2024 - Research.com Genetics in Belgium Leader Award
  • 2023 - Research.com Genetics in Belgium Leader Award

Overview

Jo Vandesompele is affiliated with Ghent University in Belgium and has an extensive publication record in the fields of biochemistry, genetics, and molecular biology, alongside medicine. Their work covers various subfields including molecular biology, cancer research, infectious diseases, biomedical engineering, and genetics.

The scientist's recent papers demonstrate a focus on molecular biology techniques and RNA research. Notable publications include:

  • The Digital MIQE Guidelines Update: Minimum Information for Publication of Quantitative Digital PCR Experiments for 2020 (2020, Clinical Chemistry)
  • The RNA Atlas expands the catalog of human non-coding RNAs (2021, Nature Biotechnology)
  • On the utility of RNA sample pooling to optimize cost and statistical power in RNA sequencing experiments (2020, BMC Genomics)
  • Closing the circle: current state and perspectives of circular RNA databases (2020, Briefings in Bioinformatics)
  • Charting Extracellular Transcriptomes in The Human Biofluid RNA Atlas (2020, Cell Reports)

Frequent co-authors of Jo Vandesompele include:

  • Pieter Mestdagh
  • Jasper Anckaert
  • Kimberly Verniers
  • Justine Nuytens
  • Annelien Morlion

The scientist has consistently published in a number of venues, with multiple contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Chemistry
  • Clinical Cancer Research
  • Nature Biotechnology
  • Briefings in Bioinformatics

Main areas of research for Vandesompele encompass:

  • Cancer-related molecular mechanisms research
  • Molecular Biology Techniques and Applications
  • RNA modifications and cancer
  • Cancer Genomics and Diagnostics
  • SARS-CoV-2 detection and testing
  • MicroRNA in disease regulation
  • RNA Research and Splicing

Best Publications

  • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

    Jo Vandesompele;Katleen De Preter;Filip Pattyn;Bruce Poppe

  • The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

    Stephen A. Bustin;Vladimir Benes;Jeremy A. Garson;Jan Hellemans

  • qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data

    Jan Hellemans;Geert Mortier;Anne De Paepe;Franki Speleman

  • miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

    Li Ma;Jennifer Young;Harsha Prabhala;Elizabeth Pan

  • Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

    Martin Peifer;Lynnette Fernández-Cuesta;Martin L. Sos;Julie George

  • A novel and universal method for microRNA RT-qPCR data normalization

    Pieter Mestdagh;Pieter Van Vlierberghe;An-Sofie De Weer;Daniel Muth

  • EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

    Jan Van Deun;Pieter Mestdagh;Patrizia Agostinis;Özden Akay

  • A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

    Zhenqiang Su;Paweł P. Łabaj;Sheng Li;Jean Thierry-Mieg

  • The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

    Jan Van Deun;Pieter Mestdagh;Raija Sormunen;Veronique Cocquyt

  • The Digital MIQE Guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments

    Jim F. Huggett;Carole A. Foy;Vladimir Benes;Kerry Emslie

  • How to do successful gene expression analysis using real-time PCR

    Stefaan Derveaux;Jo Vandesompele;Jan Hellemans

  • Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study

    Pieter Mestdagh;Nicole Hartmann;Lukas Baeriswyl;Ditte Andreasen

  • Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma

    N Bown;S Cotterill;M Lastowska;S O'Neill

  • Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project

    Chris F. Taylor;Chris F. Taylor;Dawn Field;Susanna Assunta Sansone;Susanna Assunta Sansone;Jan Aerts

  • LNCipedia: a database for annotated human lncRNA transcript sequences and structures.

    Pieter-Jan Volders;Kenny Helsens;Xiaowei Wang;Björn Menten

  • Standardization of real-time PCR gene expression data from independent biological replicates.

    Erik Willems;Luc Leyns;Jo Vandesompele

  • LNCipedia 5: towards a reference set of human long non-coding RNAs.

    Pieter-Jan Volders;Jasper Anckaert;Kenneth Verheggen;Justine Nuytens

  • Melanoma addiction to the long non-coding RNA SAMMSON.

    Eleonora Leucci;Roberto Vendramin;Marco Spinazzi;Patrick Laurette

  • Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.

    Jan Hellemans;Olena Preobrazhenska;Andy Willaert;Philippe Debeer

  • LNCipedia: a database for annotated human lncRNA transcript sequences and structures

    Pieter-Jan Volders;Kenny Helsens;Xiaowei Wang;Lennart Martens

Frequent Co-Authors

Pieter Mestdagh
Pieter Mestdagh Ghent University
Franki Speleman
Franki Speleman Ghent University
Katleen De Preter
Katleen De Preter Ghent University
Anne De Paepe
Anne De Paepe Ghent University Hospital
Nadine Van Roy
Nadine Van Roy Ghent University
Johannes H. Schulte
Johannes H. Schulte Charité - University Medicine Berlin
Genevieve Laureys
Genevieve Laureys Ghent University Hospital
Björn Menten
Björn Menten Ghent University Hospital
Raymond L. Stallings
Raymond L. Stallings Royal College of Surgeons in Ireland
Bruce Poppe
Bruce Poppe Ghent University Hospital

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